485 research outputs found

    2. Genetic prothrombotic factors in children with otogenic lateral sinus thrombosis: five case reports

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    (0) Save to: more options Genetic prothrombotic factors in children with otogenic lateral sinus thrombosis: five case reports Author(s): Zangari, P (Zangari, Paola)1; Messia, V (Messia, Virginia)1; Viccaro, M (Viccaro, Marika)2; Bottero, S (Bottero, Sergio)2; Randisi, F (Randisi, Francesco)3; Marsella, P (Marsella, Pasquale)2; Luciani, M (Luciani, Matteo)4; Locatelli, F (Locatelli, Franco)4 Source: BLOOD COAGULATION & FIBRINOLYSIS Volume: 23 Issue: 2 Pages: 158-163 DOI: 10.1097/MBC.0b013e328349cafb Published: MAR 2012 Times Cited: 0 (from Web of Science) Cited References: 20 [ view related records ] Citation Map Abstract: Lateral sinus thrombosis (LST) is an uncommon, but life-threatening complication of both acute and chronic otitis media. There is some evidence that acquired or hereditary prothrombotic disorders are risk factors for LST. The aim of this work was to evaluate the role of thrombotic screening, anticoagulant therapy or prophylaxis in patients with either acute or chronic otitis media and LST. The medical records of five children hospitalized at Pediatric Hospital Bambino Gesu of Rome because of acute or chronic otitis media complicated by mastoiditis and LST were reviewed. All children underwent laboratory workup for hypercoagulability. All the five children were found to be heterozygote for the C677T MTHFR mutation and a child presented also heterozygosity for factor V Leiden mutation. They have been successfully treated with anticoagulant therapy without sequels. Children with acute or chronic otitis media may have a prothrombotic tendency that becomes clinically evident because of the inflammatory state. Patients with a family and/or personal history of thrombosis and/or thrombophilic conditions need anticoagulant prophylaxis also in the absence of clear signs of LST. Treatment with low molecular weight is successful in patients with LST. Blood Coagul Fibrinolysis 23:158-163 (C) 2012 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins

    Jean Bottero et André Finet. — Répertoire analytique des tomes I à V

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    Dussaud René. Jean Bottero et André Finet. — Répertoire analytique des tomes I à V. In: Syria. Tome 31 fascicule 3-4, 1954. pp. 307-308

    Integrating the analytic network process (ANP) and the driving force-pressure-state-impact- responses (DPSIR) model for the sustainability assessment of territorial transformations

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    PurposeThe paper, which is based on an integrated approach that is able to aid the comprehension of complex phenomena, aims to investigate innovative models and tools in the field of sustainability assessment of territorial transformations. The model has been applied to a real case study related to the choice of alternative projects for the requalification of a downgraded urban area in Turin (Italy).Design/methodology/approachThe work proposes the use of a comprehensive key environmental indicator framework and multi‐criteria analysis to evaluate the sustainability of different strategies. The evaluation has been performed through the application of the analytical network process (ANP) and by means of a set of indicators, which have been arranged according to the Driving Force‐Pressure‐State‐Impact‐Responses (DPSIR) framework. The assessment model provides priority lists of the importance of the considered indicators and alternatives. All the analysis elements are modelled with the ANP, taking into consideration the interconnections between the indicators and their respective cumulative importance.FindingsAccording to the aim of the paper, the most important element in the performed analysis refers to the variation of the well‐being of the population, followed by the changes in the accessibility and attractiveness of the area, then by the effects on the real estate market and the presence of new cycle tracks.Originality/valueThe work is the first study at a national level and one of the first applications at an international level in research concerning the use of the DPSIR framework integrated with an ANP analysis.</jats:sec

    Il dolore e l’eterno. Lettura di Per diverse ragioni di Domenico Brancale

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    This essay will consist of a critical reading of Per diverse ragioni, the latest collection by the poet Domenico Brancale published in 2017 for Passigli. Through a transversal reading of the poetic text, the main thematic and poetic issues of the author will be analyzed. A second point of interest will be the deepening of the ontological framework and of the conceptual meanings of the collection, and it will be connected to an investigation relating to its formal and philosophical-speculative derivations

    «Sola nel letto di me stessa» Osservazioni sulla poetica di Biancamaria Frabotta ne "La materia prima"

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    This essay focuses on the poetic conception of Biancamaria Frabotta in the collection La materia prima. The literature dedicated to Frabotta’s poetry is to date very wide. However, no studies on the collection have been produced to date. In order to offer an unprecedented insight into Frabotta’s poetic work, the purpose of this study is to perform a study of the textual corpus, approached through a philosophical critical methodology of analysis. Such analysis will be divided into three paragraphs and will focus on the issues raised by the ontological and aesthetical centrality of the figure of the animal, the metaphysical conception of the poet and the theoretical compositional component. The study will provide a new epistemological reading of the second-last poetry collection of Frabotta, which will also allow for a deeper understanding of her work. A new contribution will thus enrich the critical literature on the author both in the sense of the methodology and of the research focus

    La valorizzazione dei beni culturali in aree marginali: il ruolo dell'analisi multicriteria spaziale

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    Enhancing cultural heritage in mountain regions is a crosscutting topic: environmental protection, social and cultural promotion and economic development have the same relevance and require to find a durable balance among them. Alpine areas bear geographic and permanent disadvantages. These include physical factors, such as morphology, climate, hydro-geologic risk, and human geography weaknesses, such as the low density, which prevents any arising of agglomeration economies, the isolation of local communities andthe limited accessibility. Moreover, the opportunities for strengthen the territorial development by cultural heritage are not always consensual. Conflicts between preservation of tangible and intangible cultural values for local communities and the heritage marketing according to consumers’ needs often arise. This paper proposes an integrated approach able to consider the spatial features of eachdimension of the problem and to support the definition of future development strategies. In particular, the proposed approach will be tested on a real case related to the system of historical castles located in the Valle d’Aosta Region in the North of Italy.DOI: http://dx.medra.org/10.19254/LaborEst.09.0

    Acqua, architettura, ecologia

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