475 research outputs found

    In the shadow of the church: the building of mosques in early medieval Syria

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    In his book In the Shadow of the Church: The Building of Mosques in Early Medieval Syria Mattia Guidetti examines the establishment of Muslim religious architecture within the Christian context in which it first appeared in the Syrian region, contributing to the debate on the transformation of late antique society to a Muslim one. He scrutinizes the slow process of conversion to Islam of the most important town centers by looking at religious places of both communities between the seventh and the eleventh century. The author assesses the relevancy of churches by analyzing the location of mosques and by researching phenomena of transfer of marble material from churches to mosques

    RESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS

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    RESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS De Leo Alessandra (a), Colavita Francesca (a), Arena Giuseppe (b), Mattia Elena (a) (a) Dip. di Scienze di Sanità Pubblica e Malattie Infettive “Sanarelli”, Univ. di Roma “Sapienza” (b) Casa Sollievo della Sofferenza Hospital, CSS-Mendel Institute, Roma Presenting author: De Leo Alessandra, [email protected] We have previously examined the antiviral activity of resveratrol on the replication of Epstein Barr Virus (EBV), the etiologic agent of infectious mononucleosis and associated with several types of malignancies of epithelial and lymphoid origin. In a cellular context that allows in vitro EBV activation and lytic cycle progression through mechanisms closely resembling those that in vivo initiate and enable productive infection, we found that RV inhibited EBV lytic genes expression and the production of viral particles in a dose-dependent manner

    Sviluppo di un apparato di correlazione ottica per lo studio della sedimentazione di particelle in presenza di gradienti termici

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    LAUREA MAGISTRALETermoforesi e sedimentazione sono due ambiti del mondo fisico di grande interesse e di grande sfida. Un loro studio più approfondito, sotto i punti di vista teorico e sperimentale, può condurre a grandi passi in avanti nel mondo scientifico e tecnologico. Lo sviluppo di nuove tecniche ottiche di indagine, e in particolare della Differential Dynamic Microscopy, ha permesso di combinare i vantaggi dell’analisi microscopica e dello scattering e di realizzare così sperimentazioni con strumenti ottici semplici ma potenti. Il presente lavoro di tesi si è focalizzato sulla realizzazione di un nuovo apparato sperimentale che consenta l’analisi di campioni di natura colloidale in diversi ordini di grandezza che li caratterizzano. In particolar modo, diverse configurazioni dello strumento ottico permettono di effettuare indagini che vanno dalla scala micrometrica della particella (mediante la configurazione microscopica) alla scala caratteristica della cella presa in esame (nell’ordine di grandezza dei millimetri o dei centimetri). In questa seconda casistica, approfondita nel contesto del presente lavoro, è possibile risalire, mediante l’analisi dei campi speckle con opportune tecniche di correlazione, al comportamento delle particelle senza la necessità di avere uno strumento ottico la cui capacità risolutiva arrivi fino al loro ordine di grandezza. Secondo i principi ora esposti sono quindi state analizzate delle dispersioni colloidali di polistirene (PS), di MFA e di PMMA poste in due diverse celle: una orizzontale e spessa 600 μm, l’altra verticale e spessa 5 mm. Entrambe le celle erano dotate di strumenti di controllo e monitoraggio della temperatura, con la possibilità di instaurare dei gradienti termici e di studiare con le tecniche di correlazione il comportamento dei campioni. Sono quindi stati analizzati i campi di moto instauratisi all’interno delle celle e, nel caso della cella verticale, è stata valutata la loro interazione con i fenomeni di sedimentazione.Thermophoresis and sedimentation are two areas of physics of great interest and great challenge. A deeper analysis of these phenomena, under the theoretical and experimental points of view, can lead to a great scientific and technological advance. The development of new optical techniques, and in a particular way of the Differential Dynamic Microscopy, allowed combining the advantages of both microscopic and scattering analysis, in order to realize new scientific experiments with simple and powerful optical instruments. This thesis work has analyzed the construction of a new experimental setup, which allows analyzing colloidal samples in several order of magnitude. In particular, multiple configurations of the optical instrument allow carrying out investigations ranging from the micrometre scale (using the microscopy configuration) to the characteristic scale of the cell used for the experiment, whose order of magnitude is in the order of millimeters or centimeters. In this second case, which has been analyzed in this work, it’s possible to go back, by the analysis of speckle fields with appropriate correlation techniques, to the behaviour of the particles, whose order of magnitude is below the resolution limit of the optical instrument. Colloidal samples of polystyrene (PS), of MFA and of PMMA have been analyzed in two different configurations, with the techniques above mentioned. The first cell has been used in horizontal configuration and is 600 μm thick, while the second one has been used in vertical configuration and is 5 mm thick. The temperature of the two cells has been monitored and controlled and thermal gradients have been applied to the system. The behaviour of the samples has been analyzed with correlation techniques and the velocity field of convective rolls that have grown up has been analyzed with digital programs. In the vertical cell the interaction between the convective rolls and the sedimentation processes have been studied

    Does Independence Affect Regulatory Performance? The case of national competition authorities in the European Union

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    Despite having always been assumed to be true, a relationship between the independence of regulatory agencies and their performance has never been formally tested. This paper aims at verifying whether formal regulatory independence affects the performance of national competition authorities in the EU member states. The author presents and discusses a statistical analysis which shows that greater formal independence leads competition authorities to investigate more cases and to issue more decisions

    Caterina Colombini (1304 ca.-1387) o della cugina sedotta. Una ‘ricostruzione’ della figura di Caterina attraverso i testi letterari, in Le vestigia dei gesuati. L’eredità culturale del Colombini e dei suoi seguaci, a cura di I. Gagliardi, Firenze, Firenze University Press, 2020, pp. 57-71 ISBN 978-88-5518-227-0

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    In this essay the author demonstrates that it is possible to reconstruct the figure of Caterina Colombini (1340?-1387) – Giovanni Colombini's cousin – through a group of texts: the hagiography of Caterina, the letters sent to her by Giovanni Colombini and, finally, Giovanni's biography written by Feo Belcari. The author divides his text into four parts: the first part analyzes the content of Caterina's hagiography; the second examines the linguistic form of the hagiographic text; in the third, the author analyzes the latent meaning of the window, a symbolic place where Giovanni and Caterina converse on divine topics; in the last part, to conclude, the teachings that Giovanni gives to Catherine and her spiritual daughters – the Gesuate – are analyzed

    La differenza italiana e l'aporetica del "non"

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    In this paper, the author discuss a recent volume on Antonio Rosmini’s thought, and in particular around the relationship between Rosmini and Fichte and the notion of nothingness and nothingness of love

    The album of Mattia De Rossi’s drawings. Projects for the Galleria Colonna ai Santi Apostoli

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    The study proposed here on Mattia De Rossi, a pupil of Gian Lorenzo Bernini and his most trusted collaborator, is part of an investigation that the author is doing on the figure of the architect, making use of an obvious investigative tool: his drawings. In particular, the exceptional discovery of a bound volume of about 200 drawings of Mattia is a resource of great effectiveness for the study of his professional figure. Among the sheets of the collection, those relating to the construction site of the Galleria Colonna in the eponymous palace in Piazza SS. Apostoli in Rome, are presented. These drawings explain the important contribution of Mattia and the creative process that led him to the definitive version of the central hall of the gallery. The drawings are also the only graphic documents related to the project of the Galleria Colonna, now only partially known through hypothetical reconstructions. The case of the Palazzo Colonna is similar to other projects included in the volume, which enlighten us on De Rossi's career, and which explain his position in several important Roman buildings of the second half of seventeenth centur

    A Choreographic Dialogue with Caribbean Poetry: The Sacredness of the Feminine in Walcott's Omeros (1990)

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    The aim of this paper is to show how the poetry and art of Caribbean writer Derek Walcott (1930-2017) tends to manifest and substantiate the desirable cultural transformation promoted by the work of the American anthropologist and scholar Riane Eisler. The recognition and the exaltation of symbols connected to the feminine world stand at the core of Walcott’s masterpiece Omeros. In a creative mutual dialogue between different genres and identities, the Caribbean author materialises Eisler’s attempts to forge a type of society based on a new partnership ethic. In a second perspective, this paper analyses how Walcott’s work opens the path to possible creative interdisciplinary approaches in the world of the arts. In my own contribution, as a professional dancer and choreographer, I have tried to “give voice” through movements to some episodes relating to the feminine included in Omeros

    A Female Mystic and Educator in the Medici grand Duchy: Hagiography of the Venerable Leonora Ramirez de Montalvo (1602-1659) from medieval to modern topoi, in «Rivista di Storia e Letteratura religiosa», 2019/2020-a. 55, pp. 229-265 ISSN 0035-6573

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    This article aims to take into account the biography of the Venerable Leonora Ramirez de Montalvo (1602-1659) – mystic and educator in Florence of the Medici gran duchy – written by the jesuit father Cosimo de Pazzi. The author look at demonstrate the presence of medieval topoi and, at the same time, the presence of modern topoi. The whole representation has to be read in the frame of the baroque taste, in particular for the presence of the mystical visions
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