66 research outputs found
Diagnostik von spezifischen Kognitionen bei Personen mit einem erhöhten Risiko einer manischen Episode
No full textRaphaela Irene UlrichDiplomarbeit Alpen-Adria-Universität Klagenfurt 201
Late Middle Ages and Renaissance: the forgotten contribution of Max Dvořák
No full textMax Dvořák, one of the pilasters of the Viennese school of art history, is nowadays widely known for the works of his final years as well as for writings on monument conservation. Through a reconstruction of the historical and academic context and a brief presentation of Dvořák’s studies on the transition period from the fourteenth to the fifteenth century, the author aims to show that the Bohemian scholar made an important contribution to the art historical debate of the time, for which he is hardly appreciated today.
This article examines a selection of Dvořák’s early writings from the first decade of the twenthieth century. In particular, the habilitation thesis Das Rätsel der Kunst der Brüder van Eyck (The Enigma of the Art of the Van Eyck Brothers, 1903) is consulted. While many scholars claim that there is a wide gap between his older works and those from the last years of his life, as stated by his former students Karl M. Swoboda and Johannes Wilde in the preface to Kunstgeschichte als Geistesgeschichte (1924), it is argued here that Dvořák’s point of view already presents the basic elements of his more mature conclusions at the beginning of his academic career. Likewise, it is reflected on the fact that Dvořák made a remarkable contribution to a new consideration of the transitional period between the late Middle Ages and the Renaissance, among other workd, with his Enigma, but that this is today attributed not to him but to the cultural historian Johan Huizinga and his work Autumn of the Middle Ages (1919)
Defining a Discipline: «Kunstgeschichtliche Anzeigen» as a Critical Organ for the Vienna School
No full textThis article briefly presents the often mentioned, yet not deeper investigated journal 'Kunstgeschichtliche Anzeigen' (KA), founded by Franz Wickhoff in 1904. The primary driving force behind the project was his then assistant Max Dvořák, who continued the editorship after Wickhoff’s death in 1909 until 1913. On this occasion, the founding of the journal through the unpublished correspondence between the two, which gives insight into the journal’s objectives and purpose, is retraced. Particular attention is given to the involvement of scholars from other universities as well as to the KA’s aim to establish a definition of scientifically valid research in art history. In this context, an analysis of the Vienna School’s definition of Wissenschaftlichkeit (‘scientificity’) is a central part of the article. Finally, the author reflects on the journal’s legitimacy in the broader context of the institutionalisation of the discipline of art history
Altered expression and new mutations in DNA mismatch repair genes MLH1 and MSH2 in melanoma brain metastases
No full textBrain metastases, including those of malignant melanoma (known for its high genomic instability), are the most common intracranial tumors. The main objective of this study was to investigate expression and mutation in the DNA mismatch repair system in melanoma brain metastases. Expression of MLH1, MSH2, PMS1 and PMS2 was investigated immunohistochemically in 31 melanoma metastatic tumors. Mutational analysis of MLH1 and MSH2 was performed in 17 melanoma brain metastases. Loss of MLH1 and MSH2 expression was found in 10/31 and 12/31 tumors. PMS1 (27/31) and PMS2 (28/31) expression was preserved in the majority of lesions. Potential missense mutation was found in MSH2 (exon 13) in 2/17 melanomas. Mutation in the intron sequence between exon 14 and 15 of MLH1 (exon 15) was observed in 4/17 cases. Our results indicate that the two major DNA mismatch repair genes, MLH1 and MSH2, are more frequently affected by alterations it? the DNA mismatch repair system than the helper genes PMS1 and PMS2. The presence of mutations of MSH2 and MLH1 in melanoma brain metastases, which has not been found in primary melanomas, indicates the high genomic instability of melanoma brain metastases
Altered expression and new mutations in DNA mismatch repair genes MLH1 and MSH2 in melanoma brain metastases
No full textBrain metastases, including those of malignant melanoma (known for its high genomic instability), are the most common intracranial tumors. The main objective of this study was to investigate expression and mutation in the DNA mismatch repair system in melanoma brain metastases. Expression of MLH1, MSH2, PMS1 and PMS2 was investigated immunohistochemically in 31 melanoma metastatic tumors. Mutational analysis of MLH1 and MSH2 was performed in 17 melanoma brain metastases. Loss of MLH1 and MSH2 expression was found in 10/31 and 12/31 tumors. PMS1 (27/31) and PMS2 (28/31) expression was preserved in the majority of lesions. Potential missense mutation was found in MSH2 (exon 13) in 2/17 melanomas. Mutation in the intron sequence between exon 14 and 15 of MLH1 (exon 15) was observed in 4/17 cases. Our results indicate that the two major DNA mismatch repair genes, MLH1 and MSH2, are more frequently affected by alterations it? the DNA mismatch repair system than the helper genes PMS1 and PMS2. The presence of mutations of MSH2 and MLH1 in melanoma brain metastases, which has not been found in primary melanomas, indicates the high genomic instability of melanoma brain metastases
EU cultural policy as a tool to combat crises - a discourse analysis on the use of cultural policy in deadlock
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Previous issue date: 2017-04-17Embargo set by: Colleen Fallaw for item 102620
Lift date: 2019-08-10T21:25:30Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 102620 on 2019-08-11T09:15:09Z.This Master’s thesis looks at the relationship between crises and European identity, an identity largely built by the EU’s cultural policy. I examine where this connection is made by analyzing communication from various EU institutions, as well as EU or national politicians, and newspapers. I hypothesize that the EU is referring to European identity and the common European cultural heritage in crisis situations. After conducting discourse analysis, a connection between crises and European identity or common culture is made at various places and by various people. This thesis contributes to the field of European Union Studies, by looking at how the concept of European identity through cultural policy is utilized. It also makes a contribution to the field of Cultural studies by indicating how culture can be instrumentalized and how culture can transform social relations.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2019-05-01The student, Raphaela Berding, accepted the attached license on 2017-04-13 at 17:11.The student, Raphaela Berding, submitted this Thesis for approval on 2017-04-13 at 17:11.This Thesis was approved for publication on 2017-04-17 at 09:39.DSpace SAF Submission Ingestion Package generated from Vireo submission #10751 on 2017-08-10 at 14:30:3
Die Auf- und Einlagerung von Fluorid in Zahnschmelz nach Aufbringen des Fluoridlacks Flairesse in vitro
No full textInterventions politiques dans l'économie numérique : Essais empiriques
No full textCette thèse étudie de manière empirique les interventions politiques et managériales dans l'économie numérique et analyse leur efficacité et leurs effets secondaires potentiels.Le premier chapitre met en évidence un effet politique involontaire d'un régime d'aide publique aux entreprises, mis en place dans les régions allemandes ayant un retard sur le plan économique. Nous exploitons des variations dans les conditions d'éligibilité et dans les sommes des potentielles subventions, afin d'analyser leur influence sur la propension des entreprises à adopter des services du Cloud. Les résultats empiriques montrent que plus la subvention potentielle à l'investissement est élevée, moins les entreprises sont incitées à adopter des services du Cloud. Cet effet involontaire de la politique est très pertinent pour les décideurs politiques, car l'adoption des services du Cloud a été associée à divers bienfaits pour l'entreprise, ainsi que pour l'économie dans son ensemble.Le deuxième chapitre analyse une réglementation pionnière en matière de discours haineux en ligne sur la plateforme de médias sociaux X (ex Twitter). Nous y exploitons l'introduction d'une régulation en Allemagne, qui s'applique aux réseaux sociaux, dans une approche quasi-expérimentale pour mesurer l'impact causal de la loi sur la prévalence des contenus haineux dans un groupe cible du segment germanophone de X. Les résultats impliquent une diminution significative et robuste de l'intensité et du volume des discours de haine dans les tweets abordant des sujets sensibles liés à l'immigration et à la religion. Il est important de noter que les tweets abordant d'autres sujets, ainsi que le style de tweet des utilisateurs ne sont pas affectés par le règlement, ce qui est conforme à son objectif. Ce chapitre montre que la législation visant à lutter contre les contenus en ligne préjudiciables peut réduire de manière significative la prévalence du discours de haine. Par ailleurs, il contribue à comprendre les potentiels effets que pourrait avoir le Digital Service Act, instauré par l'Union Européenne.Le troisième chapitre étudie les mécanismes de l'«économie des créateurs». Elle s'appuie sur un modèle de plateforme multi-face, mettant en relation les créateurs de contenu, les utilisateurs et (parfois) les annonceurs. Répondre aux besoins de ces différents partis est un défi complexe, comme le montre l'impact de l'«Adpocalypse» de YouTube en 2017. Lors de cet épisode, de grands annonceurs ont quitté YouTube parce qu'ils craignaient que leurs publicités soit associées à des contenus répréhensibles. Ce chapitre exploite les efforts de modération de contenu déployés par YouTube à la suite de l'Adpocalypse pour mesurer les réponses multiplateformes des créateurs et des consommateurs de contenu sur Patreon. Le modèle théorique et les données empiriques de ce chapitre confirment que les créateurs de contenu qui pratiquent le multi-homing sur YouTube et Patreon réagissent de manière stratégique et concentrent leurs efforts sur Patreon.Par conséquent, les consommateurs augmentent leur utilisation de Patreon par le biais d'adhésions, de commentaires et d'appréciations. Toutefois, nous constatons également que la modération du contenu de YouTube et le changement de comportement des créateurs et des consommateurs qui en découle entraînent une augmentation de la toxicité sur Patreon. Ces résultats indiquent que les règles de gouvernance d'une seule plateforme ne peuvent pas être considérées de manière isolée. Au contraire, les gestionnaires de plateformes et les décideurs politiques doivent prendre en compte les réactions potentielles de toutes les parties prenantes.Les trois chapitres de cette thèse démontrent que les interventions dans l'économie numérique peuvent être efficaces pour façonner les discussions en ligne, mais les particularités numériques telles que l'évolution rapide des technologies et les effets de substitution doivent être soigneusement prises en compte.This thesis empirically investigates policy and managerial interventions in the digital economy and analyses their effectiveness and potential side effects.The first chapter uncovers an unintended policy effect of a public support scheme for firms in economically lagging regions in Germany. It exploits variation in the eligibility and the size of potential investment subsidies of firms in order to analyse the relationship with the firms' propensity to adopt cloud services. The empirical results demonstrate that the higher the potential subsidy for investments, the lower the incentive for firms to adopt cloud services. This unintended policy effect is highly relevant for policy makers, as the adoption of cloud services has been linked to various benefits on the firm as well as on the aggregate economy level.The second chapter analyses the pioneering online hate speech regulation on the social media platform X. It exploits the regulation, the German Network Enforcement Act, in a quasi-experimental approach to measure the causal impact of the law on the prevalence of hateful content in a target group of the German-speaking segment of X. The results imply a significant and robust decrease in the intensity and volume of hate speech in tweets tackling sensitive migration and religion related topics. Importantly, tweets tackling other topics as well as the tweeting style of users are not affected by the regulation, which is in line with its aim. This chapter highlights that legislation for combating harmful online content can significantly reduce the prevalence of hate speech and contributes to understanding the perspective implications of the European Digital Services Act.The third chapter investigates mechanisms of the Creator Economy, which capitalizes on a multi-sided business model, connecting content creators, users, and (sometimes) advertisers. Matching the needs of these different stakeholders is a complex challenge, as evidenced by the impact of the YouTube “Adpocalypse” in 2017, when major advertisers fled YouTube due to concerns about their ads appearing alongside objectionable content. This chapter exploits YouTube's subsequent content moderation efforts following the Adpocalypse to measure the cross-platform responses of content creators and content consumers on Patreon. Focusing on content creators that multi-home on YouTube and Patreon, the theoretical model and empirical evidence of this chapter confirm that these content creators respond strategically and shift their efforts toward Patreon. As a result, consumers also increase their use of Patreon through memberships, comments, and likes. However, we also find that YouTube's content moderation and the shift by content creators and consumers that follows, results in an increase in toxicity on Patreon. These findings indicate that governance rules of a single platform cannot be looked at in isolation. Instead, platform managers and policy makers need to consider potential cross-platform reactions of all stakeholders.The three chapters of this thesis demonstrate that interventions in the digital economy can be effective in shaping online discussions, but digital particularities such as rapidly changing technologies and substitution effects need to be carefully considered
Dynamic Optical Coherence Tomography in Dermatology
No full textOptical coherence tomography (OCT) represents a non-invasive imaging technology, which may be applied to the diagnosis of non-melanoma skin cancer and which has recently been shown to improve the diagnostic accuracy of basal cell carcinoma. Technical developments of OCT continue to expand the applicability of OCT for different neoplastic and inflammatory skin diseases. Of these, dynamic OCT (D-OCT) based on speckle variance OCT is of special interest as it allows the in vivo evaluation of blood vessels and their distribution within specific lesions, providing additional functional information and consequently greater density of data. In an effort to assess the potential of D-OCT for future scientific and clinical studies, we have therefore reviewed the literature and preliminary unpublished data on the visualization of the microvasculature using D-OCT. Information on D-OCT in skin cancers including melanoma, as well as in a variety of other skin diseases, is presented in an atlas. Possible diagnostic features are suggested, although these require additional validation
Römische Fabeln auf Mühlviardlarisch
No full textThe Mühlviertel is an Austrian region belonging to the state of Upper Austria: it is one of four quarters of Upper Austria, the others being Hausruckviertel, Traunviertel, and Innviertel. It is named for the two rivers Große Mühl and Kleine Mühl. Here are Phaedrus' fables in this dialect, though the author challenges our normal understanding of the difference between language and dialect; this dialect is for him an independent language (6-7). This book with its illustration has helped me to understand Phaedrus V 9 for the first time (195): the bull went through this opening a long time ago, when he was smaller. He does not need the younger animal's advice about what he has already done many times over. The black-and-white illustrations are good, if simple. They are all sideways -- because landscape -- in a book that is in the traditional portrait frame. Among the best illustrations are those of the fox and owl and their young (57); the eagle, cat, and pig (74); the grasshopper and the owl (114); the fox and the goat (146). The cover's colored rendition of FG seems much livelier than the black-and-white (132). Does the fact that the vocabulary after each fable comes in a standardized table betray the computer-generated character of this book?This is a hardbound book (hard cover)Language note: German (Mühlviardlarisch)Leopold Pamme
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