1,721,955 research outputs found
Who are you? The genetic identity of some insular populations of Hierophis viridiflavus s.l. from the Tyrrhenian Sea
Full text linkThis work investigates the genetic identity of Hierophis viridiflavus s.l. specimens from insular populations, to determine which of the two previously identified species is present on each island. Here, the authors hypothesise about times and modes of colonization and discuss the faunistic value of the obtained results. This follows the recent proposal to consider the two clades as two different species. Specimens from the islands of Favignana, Lipari and Vulcano belong to H. carbonarius and probably all belong to putative Sicilian source populations. Conversely, all individuals from the Pontine Islands (Ponza, Palmarola, Ventotene) should be considered to belong to H. viridiflavus. Even if genetically identical to the specimens from the Tyrrhenian Italian coast, these individuals show a darker colouration, very similar to the one usually shown by H. carbonarius specimens. Considering that the Pontine H. viridiflavus populations probably have a very recent origin, the dark livery of these individuals could be the result of a rapid morphological adaptation to insular environments
Computer application of the EMC course at the University of Rome ''La Sapienza''
No full textSince 1990 an EMC course has been established for the degree on electrical engineering at the University of Rome “La Sapienza”. The EMC course is held during the fifth year and includes about 72 hours of lectures and 48 hours of computer applications and experimental test work. An overview of the computer applications developed during the EMC course at the University of Rome “La Sapienza” is presente
Computer application of the EMC course at the University of Rome 'La Sapienza'
No full textSince 1990 an EMC course has been established for the Degree on Electrical Engineering at the University of Rome 'La Sapienza'. The EMC course is held during the fifth year and includes about 72 hours of lectures and 48 hours of computer applications and experimental test work. An overview of the computer applications developed during the EMC course at the University of Rome 'La Sapienza' is presented
Expressionof urokinase plasminogen activator (UPA) in malignant and benign breast tissue:analysis by quantitative RT-PCR assays
No full textM36 EXPRESSION OF UROKINASE PLASMINOGEN ACTIVATOR
(UPA) IN MALIGNANT AND BENIGN BREAST TISSUE: ANALYSIS BY
QUANTITATIVE RT-PCR ASSAYS
Ceccarelli Francesca, Fuso Andrea, Civitelli Liana, Ranieri Ersilia, Pagni Paola,
Caprio Giuliana, Rengo Mario, Scarpa Sigfrido
Surgical Department ‘‘Pietro Valdoni’’, University of Rome ‘‘La Sapienza’’,
Rome, Italy
Background: degradation of extracellular matrix by proteolytic enzymes is an
important step for tumour invasion and metastasis; uPA is a cornerstone in this process
and it plays an essential role in migration and cell adhesion.
Patients and methods: the expression of uPA mRNA was examined in 4 breast cancer
samples (2 ductal invasive breast cancer and 2 lobular invasive breast cancer) and 4
benign breast lesions (2 fibroadenoma and 2 typical hyperplasia). We compared these
values with uPA expression of good health women leucocytes (arbitrary value = 1). We
used RT Real Time-PCR assays; uPA expression levels were normalized to the
expression level of housekeeping gene 18S.
In breast cancer group, all women were in postmenopausal state with median age of
67,25 years. Benign group women were relatively younger, with median age of 52 years.
Result: uPA expression was significantly elevated in malignant samples when
compared to the benign lesions group (5,55-folds vs 3,48-folds). Elevated uPA mRNA
levels were associated with negative steroid hormone receptor status (ER- = 11,72-folds
vs ER+ = 2,77-folds), high values of Ki67 (10% = 1,43-folds vs 70%= 13-folds) and
high clinical stage at diagnosis, with 13-folds increase in inflammatory carcinoma.
Conclusion: these data indicate that uPA is up-regulated in malignant samples and are
consistent with its role in determining invasive potential and poor prognosis in breas
The Italian archaeological mission in southern Ethiopia University of Rome La Sapienza
No full textIl convegno italo-etiopico è organizzato in collaborazione con l’ARCCH – Autorità Etiope per la Ricerca e la Conservazione del Patrimonio Culturale e l’Università di Addis Abeba e nell’ambito dell’accordo tra l’#IICAddisAbeba e l’Università di Roma La Sapienza, prima università per studi classici e del mondo antico.
Dal 2016 l’Università di Roma La Sapienza porta avanti un progetto di ricerca in Etiopia, focalizzato sulle origini di Homo sapiens e del comportamento umano moderno. Nel corso del convegno verranno presentate, in particolare, le attività di ricerca svolte in Etiopia dalla missione archeologica italiana a Gotera (Etiopia del Sud). Insieme con i principali enti locali che si occupano di ricerca e conservazione del patrimonio archeologico in Etiopia, si discuterà dei risultati ottenuti e delle prospettive future
Visual interaction: models, systems, prototypes. The Pictorial Computing Laboratory at the University of Rome ‘‘La Sapienza’’
No full textThis paper reports on the research activities
performed by the Pictorial Computing Laboratory at
the University of Rome, La Sapienza, during the last
5 years. Such work, essentially is based on the study of
humancomputer interaction, spans from metamodels of
interaction down to prototypes of interactive systems for
both synchronous multimedia communication and
groupwork, annotation systems for web pages, also
encompassing theoretical and practical issues of visual
languages and environments also including pattern recognition
algorithms. Some applications are also considered
like e-learning and collaborative work
A VLSI recurrent network of integrate-and-fire neurons connected by plastic synapses with long-term memory
Full text linkChicca E, Badoni D, Dante V, et al. A VLSI recurrent network of integrate-and-fire neurons connected by plastic synapses with long-term memory. IEEE Transactions on Neural Networks. 2003;14(5):1297-1307.Electronic neuromorphic devices with on-chip, on-line learning should be able to modify quickly the synaptic couplings' to acquire information about new patterns to be stored (synaptic plasticity) and, at the same time, preserve this information on very long time scales (synaptic stability). Here, we illustrate the electronic implementation of a simple solution to this stability-plasticity problem, recently proposed and studied in various contexts. It is based on the observation that reducing the analog depth of the synapses to the extreme (bistable synapses) does not necessarily disrupt the performance of the device as an associative memory, provided that 1) the number of neurons is large enough; 2) the transitions between stable synaptic states are stochastic; and 3) learning is slow. The drastic reduction of the analog depth of the synaptic variable also makes this solution appealing from the point of view of electronic implementation and offers a simple methodological alternative to the technological solution based on floating gates. We describe the full custom analog very large-scale integration (VLSI) realization of a small network of integrate-and-fire neurons connected by bistable deterministic plastic synapses which can implement the idea of stochastic learning. In the absence of stimuli, the memory is preserved indefinitely. During the stimulation the synapse undergoes quick temporary changes through the activities of the pre- and postsynaptic neurons; those changes stochastically result in a long-term modification of the synaptic efficacy. The intentionally disordered pattern of connectivity allows the system to generate a randomness suited to drive the stochastic selection mechanism. We check by a suitable stimulation protocol that the stochastic synaptic plasticity produces the expected pattern of potentiation and depression in, the electronic network. The proposed implementation requires only 69 x 83 mum(2) for the neuron and 68 x 47 mum(2) for the synapse (using a 0.6 mum, three metals, CMOS technology) and, hence, it is particularly suitable for the integration, of a large number of plastic synapses on a single chip
Preliminary report on the 2022 fieldwork season of the joint mission NCAM - University of Rome “La Sapienza”
Full text linkThe paper offers an overview of the 2022 research activities of the joint mission NCAM - University of Rome “La Sapienza”. The work at the Kushite temple of Hujair Gubli is first discussed, then the results of a small survey between Zuma and Magal are presented, with the discovery of previously unknown rock-art and tumuli sites. Finally, documentation and museum activities are briefly mentioned, and the perspectives for future research are sketched out
Ugo Bianchi (éditeur), Transition Rites. Cosmic, Social and Individual Order. Proceedings of the Finnish-Swedish-Italian Seminar held at the University of Rome « La Sapienza », 24th-28th March 1984
No full textGraulich Michel. Ugo Bianchi (éditeur), Transition Rites. Cosmic, Social and Individual Order. Proceedings of the Finnish-Swedish-Italian Seminar held at the University of Rome « La Sapienza », 24th-28th March 1984. In: L'antiquité classique, Tome 57, 1988. pp. 461-463
A review of suicides by burning in Rome between 1947-1997 examined by Pathology Department of the Istitute of Forensic Medicine, University of Rome "La Sapienza"
Full text linkThe 34 cases of suicide by self-immolation admitted to the Institute of Forensic Medicine, University of Rome ‘La Sapienza’, during a 50-year period (1947–1997) were investigated. The nature of this phenomenon in relation to sex, age of the victims, location of the suicides and combination of methods used is discussed. Finally the distribution and extent and characteristics of the lesions are considered from a forensic point of view
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