24 research outputs found
CORONARY ATHEROSCLEROSIS STAGING IN PATIENTS DIAGNOSED BY DIFFERENT DEFINITION OF METABOLIC SYNDROME
No full textBackground and Aims: Metabolic Syndrome (MS) is associated to an
increased rate of CHD in general population. However it is not yet clear
which current definition of MS is more useful to screen patients with a
higher risk to have worse atheromasic coronary lesions. Our aim was to
evaluate if different MS definitions are able to differently detect patients
with more serious coronary lesions.
Methods: We consecutively enrolled 184 patients (M:63.6%, W:36.4%;
Mean age: 57,9±10,4 years) with symptoms usually related to reduced
coronary reserve. We classified the coronary lesions as “minimal” or
“serious” on the basis of the indication of revascularization. The patient
were then classified as MS affected or not on the basis of the WHO, ATP
III, and IDF suggested criteria.
Results: The WHO MS definition included the 64% of serious patients,
The ATP III MS definition the 63%, and the IDF MS definition the 72%.
Parameters significantly associated to the worse coronary lesions were the
Waist-Hip ratio (OR 5.3, 95%CI 1.7-11.6) and the diagnosis of diabetes
(OR 8.1, 95%CI 1.2-15.2). No one of the components of the MS appeared
to be significantly associated to the worse lesions in any of the applied MS
definitions.
Conclusion: the IDF definition of MS appears to include a larger
quantity of patients with worse coronary lesions that the WHO and ATP III
ones. However it is not clear if it is the simple effect of unspecific cut-off
applications to high-risk subjects or if it could have a concrete pathogenetic
basis
Production and characterization of xylanases of a Bacillus strain isolated from soil
No full textXylanase production was performed by growing a Bacillus isolate on agricultural by-products, wheat straw, wheat bran, corn cobs and cotton bagasse. A maximum xylanase activity of 180 U/ml was obtained together with a cellulase activity of 0.03 U/ml on 4 (w/v) corn cobs. Electrophoretic analysis showed the presence of three endo-beta-1, 4-xylanases having molecular weights of about 22, 23 and 40 kDa. Xylanolytic activity was stable up to 50degreesC in the pH range of 4.5-10 and the highest activity was observed at 70degreesC and pH 6.5
The severity of coronary atherosclerosis in diabetic and non-diabetic metabolic syndrome patients diagnosed according to different criteria and undergoing elective angiography
No full textOur aim in this study was to evaluate the relationship between metabolic syndrome (MS) as defined by different criteria and the severity of coronary lesions in a sample of diabetic and non-diabetic patients undergoing elective coronary angiography. All patients had blood and urine tests, physical examinations were performed before angiography, and finally they were classified based on three criteria (World Health Organisation-WHO, Adult Treatment Panel-ATP III and International Diabetes Federation-IDF). Eighty-eight patients were diabetic, and 96 patients were non-diabetic. Among all patients, diabetics had significantly higher Gensini scores (P < 0.001). According to WHO criteria (P = 0.005) and IDF criteria (P = 0.015) metabolic syndrome patients had higher Gensini scores, but for ATP III criteria difference was not significant. When we evaluated diabetics and non-diabetics separately, non-diabetic patients with MS had significantly higher scores with WHO definition (P = 0.015) and mildly higher but not significant values with other MS criteria (P = 0.057 for both IDF and ATP III). Neither any one of MS components nor gender revealed significant relationship with coronary disease severity. In our study with a cohort of Turkish patients undergoing elective coronary angiography; we concluded that MS should be taken into consideration, especially in non-diabetic patients
Biološko uklanjanje cijanida s pomoću bakterije Klebsiella pneumoniae
No full textIn this study, optimization conditions for cyanide biodegradation by Klebsiella pneumoniae strain were determined to be 25 °C, pH=7 and 150 rpm at the concentration of 0.5 mM potassium cyanide in the medium. Additionally, it was found that K. pneumoniae strain is not only able to degrade potassium cyanide, but also to degrade potassium hexacyanoferrate(II) trihydrate and sodium ferrocyanide decahydrate with the efficiencies of 85 and 87.5 %, respectively. Furthermore, this strain degraded potassium cyanide in the presence of different ions such as magnesium, nickel, cobalt, iron, chromium, arsenic and zinc, in variable concentrations (0.1, 0.25 and 0.5 mM) and as a result the amount of the bacteria in the biodegradation media decreased with the increase of ion concentration. Lastly, it was also observed that sterile crude extract of K. pneumoniae strain degraded potassium cyanide on the fifth day of incubation. Based on these results, it is concluded that both culture and sterile crude extract of K. pnemoniae will be used in cyanide removal from different wastes.U radu su određeni optimalni uvjeti za biorazgradnju cijanida s pomoću bakterije Klebsiella pneumoniae u podlozi s dodatkom 0,5 mM kalijevog cijanida, i to: temperatura od 25 °C, pH=7 i brzina vrtnje od 150 rpm. Osim toga, utvrđeno je da K. pneumoniae može osim kalijevog cijanida razgraditi i kalijev heksacijanoferat(II) trihidrat s 85 % učinkovitosti i natrijev ferocijanid dekahidrat s 87,5 % učinkovitosti. Ovaj je soj razgradio kalijev cijanid i u prisutnosti različitih iona, kao što su: magnezijevi, niklovi, kobaltovi, željezovi, kromovi, arsenovi i cinkovi ioni, u koncentracijama od 0,1; 0,25 i 0,5 mM. S povećanjem koncentracije iona smanjila se količina bakterija u podlozi. Također je utvrđeno da je sterilni supernatant bakterije K. pneumoniae u potpunosti razgradio kalijev cijanid peti dan inkubacije. Iz dobivenih je rezultata zaključeno da se kultura stanica i sterilni supernatant bakterije K. pneumoniae mogu upotrijebiti za uklanjanje cijanida iz otpadnih voda i tala
Beachrock formation on the coast of Gokceada Island and its relation to the active tectonics of the region, northern Aegean Sea, Turkey
No full textThere are beachrock formations in 5 different sections of the south coast of Gokceada, Turkey's largest Aegean island. These beachrocks form two different groups in terms of layering characteristics, delta O-18 and delta C-13 stable isotope compositions, consecutive cementation structures, and C-14 dating. The West Group beachrocks, to the west, were dated to 4010-5830 BP, while the East Group beachrocks were dated to 620-2390 BP. The beachrock formations in both groups are separated by the NE-SW-trending Ugurlu Fault. The Ugurlu Fault is a right lateral, strike slip with reverse component oblique fault, and is an active fault within the North Anatolian Fault Zone. In the period between the formation of the two beachrock groups (2390-4010 BP), an earthquake was responsible for the destruction of Gokceada Yenibademli mound and the development of two generations of beachrock. (C) 2015 Elsevier Ltd and INQUA. All rights reserved.Research Fund of the Canakkale Onsekiz Mart University (COMU-BAP) [2012/008]The findings obtained from this study comprise a portion of the doctorate of the 1st author ( M.A.) and were partially supported by supported by Research Fund of the Canakkale Onsekiz Mart University (COMU-BAP, Project Number: 2012/008). Muhammed Zeynel Ozturk and Ismail Onur Tunc are thanked for their contribution to field studies and sample preparation, and we are grateful to Mustafa Bozcu for his help with petrographic determinations
Erzeugung von Futterpflanzensaatgut für den türkischen Bedarf und den Export nach Deutschland
No full textQuercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities
No full textThe presented study comprises the one-pot synthesis and the characterization of quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles (Ch/Q- and Ch/CA-Ag NPs), and their antibacterial and anticancer activities. The formation of Ch/Q- and Ch/CA-Ag NPs has been confirmed by ultraviolet–visible (UV–vis) spectroscopy, Fourier-transform infrared (FTIR) spectroscopy, and transmission electron microscopy (TEM). The characteristic surface plasmon resonance (SPR) absorption band has been found at 417 and 424 nm for Ch/Q- and Ch/CA-Ag NPs, respectively. The formation of a chitosan shell comprising quercetin and caffeic acid, which surround the colloidal core Ag NPs, was confirmed by UV–vis, and FTIR analyses, and monitored by TEM microscopy. The size of nanoparticles has been determined as 11.2 and 10.3 nm for Ch/Q- and Ch/CA-Ag, respectively. The anticancer activity of Ch/Q- and Ch/CA-Ag NPs has been evaluated against U-118 MG (human glioblastoma) and ARPE-19 (human retinal pigment epithelium) cells. Both NPs showed anticancer activity, but Ch/Q-Ag NPs seemed to be more effective on cancer cell lines (U-118 MG) in comparison to healthy ones (ARPE-19). Furthermore, the antibacterial activity of Ch/Q- and Ch/CA-Ag NPs against Gram-negative (P. aeruginosa and E. coli) and Gram-positive (S. aureus and S. epidermidis) bacteria was determined, and dose-dependent antibacterial effects were found
Eolianite and coquinite as evidence of MIS 6 and 5, NW Black Sea coast, Turkey
No full textThis paper discusses the implications of a lowstand carbonate eolianite and overlying transgressive sequence of coquinite at Sile on the Turkish Black Sea coast based on composition, depositional characteristics and optical age estimations. The cross-bedded eolianite is a mixed ooid quartz grainstone in composition, yielding a depositional age matching MIS 6. It formed at the backshore of the paleobeach with the supply of sediment the from the beach face and offering insights into the drift of mixed shallow marine carbonates and siliciclastics together with radial ooids by onshore winds from a subaerially exposed high- to low-energy ooid shoals and oolitic sand complexes which developed parallel to the shoreline on the shallow shelf margin. During this lowstand, a low-relief dune retaining a record of opposing paleowind directions than that of prevalent northeasterly winds of today appears to have been lithified to form dune rock (aeolinite) under drier conditions compared to the present. Coinciding with MIS 5e, shallow marine coquina beds resting unconformably on the eolianite indicate the occurrence of the Mediterranean transgression during the last interglacial, as confirmed by benthic foraminifera within the high-salinity tolerant coquina shells. (C) 2017 Elsevier B.V. All rights reserved.Scientific and Technological Research Council of Turkey (TUBITAK) [113Y418]; Turkish Academy of Sciences (TUBA)The first author wishes to thank the Scientific and Technological Research Council of Turkey (TUBITAK) (project number: 113Y418) and Turkish Academy of Sciences (TUBA) for financial support. Graham H. Lee is thanked for proof-reading the text. Mustafa Avcioglu is thanked for assisting with the field work. Critical reviews by anonymous referees contributed much for the improvement of the paper
Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density
No full textIn the present study, we examined the effect of nano-selenium (nano-Se) and stocking density (SD) on antioxidant status, immune response, and DNA damage in broiler chickens. A total of 480 one-d-old male broilers (Ross 308) were randomly divided into 4 treatments each including 8 replicates for 42 days. A 2 x 2 factorial arrangement of groups for two dietary selenium forms (inorganic or nano) and two stocking densities [low = 12 birds/m(2) (LSD) and high = 18 birds/m(2) (HSD)] was conducted. Starter, grower, and finisher diets were formulated based on corn-soybean meal according to recommendations of Aviagen. There were no significant differences in the lymphoid organ index due to high stocking density or nano-Se. Neither HSD nor dietary nano-Se had an effect on blood heterophil: lymphocyte ratio, serum corticosterone, glutathione, superoxide dismutase, and malondialdehyde levels. Serum interferon-gamma, interleukin 12, and interleukin 18 levels were not affected either by HSD or by dietary nano-Se. However, an interaction was witnessed between SD and dietary Se form for serum interferon-gamma (P < 0.05). HSD increased the DNA damage in lymphocyte (P < 0.05), but dietary nano-Se had no significant effect on it. In conclusion, HSD and dietary nano-Se may not affect the organ index, stress indicators, and immune function, but dietary nano-Se decreased the possible negative effect of HSD on serum interferon-gamma. HSD increased the DNA damage but dietary nano-Se had no effect
The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments
No full textThis is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Springer Science+Business Media B.V.The partitioning of steroid estrogens in wastewater treatment and receiving waters is likely to influence their discharge to, and persistence in, the environment. This study investigated the partitioning behaviour of steroid estrogens in both laboratory and field studies. Partitioning onto activated sludge from laboratory-scale Husmann units was rapid with equilibrium achieved after 1 h. Sorption isotherms and Kd values decreased in the order 17α-ethinyl estradiol > 17α-estradiol > estrone > estriol without a sorption limit being achieved (1/n >1). Samples from a wastewater treatment works indicated no accumulation of steroid estrogens in solids from primary or secondary biological treatment, however, a range of steroid estrogens were identified in sediment samples from the River Thames. This would indicate that partitioning in the environment may play a role in the long-term fate of estrogens, with an indication that they will be recalcitrant in anaerobic conditions.EPSR
