113,129 research outputs found

    Data Set of PLOS Computational Paper PCOMPBIOL-D-18-02181R1

    No full text
    Figures Data of PLOS Computational paper:Modeling of the axon plasma membrane structure and its effects on protein diffusionAuthors: Yihao Zhang, Anastasios V. Tzingounis, and George LykotrafitisCorresponding Author: George Lykotrafitis, Ph.D.University of ConnecticutStorss, CT UNITED STATES</div

    Biology and management of freesia flower specking caused by Botrytis cinerea

    No full text
    There is no published research regarding postharvest infection of freesia flowers by Botrytis cinerea. Although, infection problems have concerned freesia growers and wholesalers in recent years. The overall objectives of this study were firstly to evaluate the factors affecting B. cinerea postharvest disease establishment and secondly to evaluate a range of novel potential treatments to reduce postharvest freesia infection. These treatment options include plant activators such as acibenzolar-S-methyl and methyl jasmonate and biotic (Aureobasidium pullulans) and abiotic (UV-C irradiation) biological/elicitors agents. Research was undertaken in an attempt to explain the variation in B. cinerea incidence on cut freesia flowers as noted by the UK importer Zwetsloots & Sons Ltd. in 2000. Higher monthly rejections of freesia flower stems throughout 2000 due to B. cinerea infection were recorded during spring (April-May), early summer (June) and autumn (October). Comparatively higher proportions of rejected freesia stems were associated with glasshouse temperatures ranging from 13-17°C. In the presence of B. cinerea inoculum on freesia petal surface, temperature was not a limiting factor for disease establishment. Incubation of artificially inoculated freesia flowers at 12°C resulted in overall higher disease severity and lesion numbers compared to flowers incubated at 5 or 20°C. In contrast, relative humidity was the most important factor for postharvest infection by B. cinerea. Elicitor based strategies for IPM using the potent activator acibenzolar provided limited protection of freesia flowers against B. cinerea when applied postharvest. Acibenzolar significantly reduced disease severity, lesion numbers and lesion diameters compared to the untreated control when applied at 0.15 g A. 1. U1. Methyl jasmonate (MeJA) applied as gas, pulse and spray generally suppressed B. cinerea disease on cut freesia flowers. Disease severity, lesion numbers and lesion diameters of flowers gassed with 0.1 μL MeJA L"' were reduced by 56,43 and 37%, respectively compared to untreated control flowers. Gaseous MeJA treated freesia flowers at 0.1 μL L"1 increased PPO activity by 57% compared to untreated controls 24h after MeJA treatment. After 36h of incubation at 20°C, disease severity, lesion numbers and lesion diameters of gaseous MeJA treated flowers were reduced by 68,56 and 50%, respectively, compared to the untreated controls. However, PAL activity in MeJA treated freesia flowers did not decrease significantly over time compared to untreated control 12h post-inoculation and thereafter. These findings suggest that MeJA treatment might suppress the action of PAL in the phenylpropanoid pathway and consequently block SA production. UV-C irradiation might be used in an integrated postharvest disease management program for freesia flowers. UV-C irradiation after artificial inoculation resulted in markedly reduced B. cinerea disease severity scores and lesion numbers. In detail, UV-C irradiation of cut freesia flowers with 0.5,1,2.5 and 5 kJ m''` reduced disease severity by up to 44,70,74 and 59% and lesion numbers by up to 37,62,68 and 60%, respectively. UV-C irradiation at 1 kJ M-2 before artificial inoculation slightly reduced disease severity and lesion numbers possibly by inducing defence responses. However, the limited disease suppression suggested that apparently B. cinerea could overcome the UV-C induced effect. The effect of preharvest treatments on freesia crops with acibenzolar was investigated in glasshouse trials in view to suppress postharvest B. cinerea infection via SAR induction. Acibenzolar was effective in selected treatments and conditions. Disease pressure varied over the 3 years and over varieties tested. However, it was unclear whether acibenzolar induced systemic and/or local defence responses. The latter was supported by biochemical investigations in 2001 which suggested that acibenzolar did not induce PAL activity. In contrast, preharvest MeJA treatment resulted in markedly systemic protection of treated flowers compared to untreated ones. MeJA efficacy was dependent on variety and on postharvest incubation temperatures. Disease severity, lesion numbers and lesion diameters on MeJA treated freesia var. `Dukaat' flowers incubated at 20°C were reduced by 56,61, and 49% compared to controls, respectively. Also, disease severity, lesion numbers and lesion diameters on MeJA treated `Cote d'Azur' flowers incubated at 20°C were reduced by 36,26, and 49% compared to controls, respectively

    Haralampos V. Harissis, Anastasios V. Harissis, Apiculture in the Prehistoric Aegean. Minoan and Mycenaean Symbols Revisited

    No full text
    La publication, presque simultanée mais indépendante, ces dernières années, de trois études portant sur l’abeille et l’apiculture démontre un intérêt scientifique important pour la place centrale qu’occupe l’abeille dans la vie économique, politique et religieuse des Grecs anciens. Parmi ces études, celle de Haralampos et Anastasios V. Harissis se concentre sur la présentation des témoignages relatifs au monde de l’abeille dans l’Égée préhistorique. Fidèles à l’approche historique, les A. che..

    Ενεργοποίηση του οξυγόνου από αμφίφιλα σύμπλοκα του βαναδίου V(ΙV) και V( V) στα έλαια.

    No full text
    Oxygen can be activated in the presence of transition metals and produce reactive oxygen species. Reactive oxygen species (ROS) in low concentrations are necessary for the defence of human health against damaging agents such as bacteria and viruses. However, ROS are strong oxidative agents and large amounts of reactive oxygen species can be a weapon against the human body, because ROS can interact with biological targets such as DNA, proteins and lipids. As a result of this interaction, humans suffer from various chronic and degenerative diseases such as cancer, Parkinson, Alzheimer disease, aging and others. The human organism in order to protect itself from such diseases has developed a system that controls the balance between oxidative agents (ROS) and antioxidants (reduction molecules). One of the most important antioxidant sources is edible oils (mainly olive oils), which contain large amounts of polyphenols. Besides polyphenols, edible oils also contain lipids. Because of the edible oil’s composition, that is similar with cellular wall composition, edible oils can be used as useful biomimetic media of cellular walls. The present master thesis studies the reaction of oxygen activation which is catalyzed by amphiphilic vanadium complexes such as VOC18DEA and VOC18DPA, synthesized in the bioinorganic laboratory of Dr. Anastasios Keramidas. The study has been focused on various parameters that affect the oxygen activation in vegetable oils, such as the presence or the absence of vanadium complexes, oxygen, polyphenols, tyrosol and tocopherol. This study aims to help clarify the mechanism of cellular wall oxidation by ROS and to the characterization of vegetable oils according to their antioxidant content. In this study we used electrochemical techniques (cyclic voltammetry, linear sweep), spectroscopic techniques (EPR, NMR, UV-Vis) and analytical techniques (iodometric titration). The result from this research was that oxygen can be activated by vanadium. Also, the research shows that phenols, such as tocopherol and tyrosol, can trap the radicals that are generated from oxygen activation and that polyphenols can act as prooxidants that accelerate oxygen activation.Epaminontas Leontidis Anastasios Keramidas Anastasios TasiopoulosComplete

    "Etymological atlas" of human body in Hodegos of Anastasios of Sinai

    No full text
    `Oδηγόζ (The Guide) is the most famous work of Anastasios of Sinai, the theological writer from the 7th-8th century. It is some sort of a handbook for fighting the heresies, in the first place Monophysitism and Monotheletism. Anastasios is discussing the terms, i.e. the categories, which the believer should use if he wants to be orthodox. In the second chapter Anastasios brings the definitions of theological technical terms which he will be using in his polemics. To strengthen his argumentation he quotes more than 120 etymologies of different words. Among them are 17 etzmologies of the names of the parts of human body. We are talking about some of them in this work. [Projekat Ministarstva nauke Republike Srbije, br. 1777032: Tradicija, inovacija i identitet u vizantijskom svetu

    Albanski nadškof Anastasios

    No full text
    In recent years, several disputes between Orthodox churches over jurisdictional and politico-ideological matters have raised questions about Eastern Orthodoxy’s commitment to peace. However, as a Christian denomination, Eastern Orthodoxy is theologically centred around the fundamental Christian values of love and peace. To illustrate how Eastern Orthodoxy can inspire a life devoted to peace, this article focuses on Anastasios Yannoulatos (b. 1929), the current Archbishop of the Albanian Orthodox Church, whose life constitutes a concrete Eastern Orthodox example of peace. Firstly, Archbishop Anastasios’ life story and core theological ideas are presented, and secondly, his contribution to peace is briefly highlighted.V zadnjih letih je več sporov med pravoslavnimi cerkvami glede pristojnosti in politično-ideoloških vprašanj sprožilo vprašanja o zavezanosti vzhodnega pravoslavja miru. Vendar pa je vzhodno pravoslavje kot krščanska veroizpoved teološko osredotočeno na temeljne krščanske vrednote ljubezni in miru. Da bi ponazorili, kako lahko vzhodno pravoslavje navdihuje življenje, posvečeno miru, se ta članek osredotoča na Anastasiosa Yannoulatosa (r. 1929), sedanjega nadškofa albanske pravoslavne cerkve, katerega življenje je konkreten vzhodnopravoslavni primer miru. Najprej so predstavljeni življenjska zgodba in temeljne teološke ideje nadškofa Anastasiosa, nato pa na kratko še njegov prispevek k miru

    SMITten for KCNQ Channels

    No full text

    author-bios-SRD-19-0063.R1 – Supplemental material for The Network Structure of Police Misconduct

    No full text
    Supplemental material, author-bios-SRD-19-0063.R1 for The Network Structure of Police Misconduct by George Wood, Daria Roithmayr and Andrew V. Papachristos in Socius</p

    New historical evidence for Anastasios Emm. Papas

    No full text
    No AbstractThe author’s attention has been drawn to the existence of this historicalevidence in the National Archives of Vienna, by his friend the writer EteoclesGregoriadis together with the numbers of the relevant files. Most of the documents were written in the old German script. Thus the author asked for the help of his friend and former colleague at the University of Thessaloniki and director of the Goethe Institute, Graf Kurt v. Posadowsky, for reading andstudying those documents. Without his help this study would have been impossible. This new evidence concerns the sojourn of Anastasios Papas·—son of Emmanuel Papas, leading figure of the Greek Revolution—in Austria andGermany between the 3rd January and 11th March 1822. There is informationabout his short imprisonment in Trieste, after his arival from Vienna. He then visits various towns in Germany and after negotiations with the Philhellene professor Fr. Thiersch in Munich, he purchases large quantities of ammunition to be despatched to Greece. He finally arrives in Greece early in 1824, and takes part—together with his three brothers who were already fighting—in the struggle for the liberation of the common great fartheland

    Potassium Channel Gain of Function in Epilepsy: An Unresolved Paradox

    No full text
    Exome and targeted sequencing have revolutionized clinical diagnosis. This has been particularly striking in epilepsy and neurodevelopmental disorders, for which new genes or new variants of preexisting candidate genes are being continuously identified at increasing rates every year. A surprising finding of these efforts is the recognition that gain of function potassium channel variants are actually associated with certain types of epilepsy, such as malignant migrating partial seizures of infancy or early-onset epileptic encephalopathy. This development has been difficult to understand as traditionally potassium channel loss-of-function, not gain-of-function, has been associated with hyperexcitability disorders. In this article, we describe the current state of the field regarding the gain-of-function potassium channel variants associated with epilepsy (KCNA2, KCNB1, KCND2, KCNH1, KCNH5, KCNJ10, KCNMA1, KCNQ2, KCNQ3, and KCNT1) and speculate on the possible cellular mechanisms behind the development of seizures and epilepsy in these patients. Understanding how potassium channel gain-of-function leads to epilepsy will provide new insights into the inner working of neural circuits and aid in developing new therapies. </jats:p
    corecore