1,720,971 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Umpolung of 1-alkoxy-3-acyloxy-1,3-dienes with sulfur dioxide and its application in polypropionate synthesis
No full textUnder appropriate conditions sulfur dioxide reacts with 1,3-dienes in the hetero-Diels-Alder fashion. In the case of 1-alkoxy-1,3-dienes the 6-alkoxy-3,6-dihydro-1,2-oxatiin-2-oxides (sultines) so-obtained can be ionized in the presence of Lewis or protic acid, thus realizing Umpolung of these electron-rich systems. The zwitterionic intermediates can be trapped as electrophiles with enoxysilanes (oxyallylation) to generate substituted silyl alkenylsulfinates. Desilylation of the latter under acidic conditions leads to intermediate allylsulfinic acids, which, after retro-ene desulfitation, produce 4-alkoxyhept-6-en-2-one core, a valuable fragment in polyketide natural product synthesis. This new SO2 reaction cascade, hetero-Diels-Alder addition/oxyallylation/retro-ene desulfitation (Vogel's cascade), was expanded to 1,3-dioxy-1,3-dienes. It was demonstrated that 1-alkoxy-3-(trialkylsilyl)oxy-1,3-dienes (Danishefsky's dienes) undergo ene reaction with sulfur dioxide due to migratory properties of trialkylsilyl substituent. The use of 1-alkoxy-3-acyloxy-2-methyl-1,3-pentadienes and enoxysilanes in Vogel's cascades resulted in an efficient synthesis of stereotriads containing keto and enol ester functions, suitable for further chain elongation. Good anti,syn and anti,anti selectivities were achieved using of (Z)- and (E)-enoxysilanes, respectively. The synthetic potential of the method was demonstrated by the short synthesis of 3,5-dihydroxycyclohexanone subunit of baconipyrones A and B as well as that of the hydroxydiketone subunit of baconipyrones C and D ((-)-(4S,6S)-4,6-dimethyl-5-hydroxynonan-3,7-dione). Further applications were shown by expeditious formal asymmetric total synthesis of rifamycin S and initiation of synthesis of C(27)-C(37) fragment of brasilinolides A and C. The method was extended to other π-nucleophiles, such as allylsilanes. A small library of differently substituted homoallylic ethers was synthesized to demonstrate utility of this new approach. Iterative Vogel's cascade employing newly obtained fragments provided long-chain polypropionate fragments such as (-)-(1Z,2S,3S,7S,8R,9R)-1-ethylidene-9-hydroxy-2,8-dimethyl-3,7-bis((1S,1'S)-phenylethoxy)-5-methylene-undec-1-yl benzoate in a very short and efficient way. Further generalization of π-nucleophiles led to the discovery of new ene reactions of SO2 with allylgermanes and allylboronates. A number of new chiral auxiliaries were prepared and tested in order to improve chemo- and diastereoselectivity in diene reactions with sulfur dioxide. The results demonstrated the superiority of inexpensive and readily available 1-arylethanols (and particularly 1-phenylethanol) over other types of chiral auxiliaries
Polypropionate building blocks based on sulfur dioxide cycloadditions
No full textSCGCDIPLOMES; GR - 53 324; ICO; . Consultable sur demande à la Bibliothèque de l'EPFL / Offered in consultation at the EPFL library
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Synthesis of Optically Active 5-Alkoxy-6-methylcyclohex-2-en-1-ones and 4-Alkoxy-5-methylcyclopent-1-enyl Benzoate
No full textThe reaction of (-)-(1E,3Z)-2-methyl-1-((1S)-1-phenylethoxy)penta-1,3-dien-3-ol benzoate with allyltrimethylsilane in SO,- and in the presence of a catalytic amount of Tf2NTMS gives a silyl sulfinate intermediate that furnishes (-)-(6Z,1'S,4S,5S)-5-methyl-4-(1'-phenylethoxy)octa-1,6-dien-6-yl benzoate after acidic workup. The latter undergoes ring-closing, metathesis producing (-)-(2S,3S)-2-methyl-3-((1S)-1-phenylethoxy)cyclopent-5-en-1-yl benzoate. It has been converted also into the corresponding trimethylsilyl enol ether. After oxidation, an enone is obtained that undergoes ring-closing metathesis giving (-)-(5S,6S)-6-methyl-5-((1S)-1-phenylethoxy)cyclohex-2-en-1-one.LGS
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