284,824 research outputs found
Síndrome de turcot relato de dois casos
No full textOs autores descrevem dois pacientes com associação de polipose intestinal e tumor do sistema nervoso central (síndrome de Turcot), discutindo aspectos clínicos, genéticos e terapêuticos
Two PMS2 mutations in a Turcot syndrome family with small bowel cancers
No full textAbstract
We report the clinicopathological, genetic, and immunohistochemical characterization of an atypical Turcot syndrome (TS) family with small bowel cancer. The tumor family history of a patient with cafè-au-lait spots (CALS) and early onset adenomas, duodenal cancer, and glioblastoma was positive for colonic adenoma (mother), jejunal (maternal grandfather), lung (father), and colorectal (paternal uncle) cancers. PMS2 genetic testing identified the nonsense 1951C>T (Q643X) and the missense 161C>T (S46I) mutations. PMS2 expression was absent in the proband's duodenal cancer with high microsatellite instability. The normal cells also displayed no PMS2 expression and some degree of instability. Our findings point out the association between PMS2 and TS, and support the hypothesis that patients with a few polyps, small bowel tumors with a very early onset, glioblastoma, and CALS should be considered as a variant of hereditary nonpolyposis colorectal cancer. A recessive model of inheritance caused by compound heterozygous mutations was consistent with the observed severe clinical phenotype and has important implications for predicting cancer risk in both the proband and his relatives
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Diffusive author(s), cohesive author: Analysis of S/N (1994)
No full textThis study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
The vanishing author in computer-generated works: a critical analysis of recent Australian case law
No full textAbstract
The use of software is ubiquitous in the creation of many copyright works, yet the requirement in copyright law that every work have a human author who engages in independent intellectual effort means that its use may prevent copyright subsistence. Several recent Australian cases have refocused attention on authorship as an essential criterion of copyright subsistence, and these cases suggest that much computer-produced output may be authorless and thus lack copyright protection. This article, the first in a two-part series, analyses how each case deals with the question of authorship of computer-produced works and why the use of software diminishes copyright protection for a significant number of computer-generated works. The article critiques the application of conventional notions of human authorship developed in the pre-computer age to modern productions and suggests alternative approaches to authorship that satisfy both the major objectives of copyright policy and the need to adapt to the computer age. The article argues that, without a broader judicial approach to authorship of computer-generated works, Parliament must remedy the lacuna in protection for these ‘authorless’ works. Possible solutions for reform are suggested. In a forthcoming article, the author comprehensively examines those reform proposals
Pigmy resonances, transfer, and separable potentials
No full text© 2017 Author(s). In this contribution we make a short review of recent progress on topics of current interest in nuclear physics and nuclear astrophysics. In particular, we discuss a re-analysis of the extraction of the dipole response of the pigmy resonance in 68 Ni based on a continuum discretized coupled-channels calculation in relativistic Coulomb excitation experiments. We also discuss the forthcoming progresses made by our group on the Alt-Sandhas-Grassberber approach to (d,p) reactions and future expectations. The role of separable potentials in solving such equations with a test case based on applications of such potentials to phase-shift analysis is also presented
Na2Ti6O13 Thin films as Anode for Thin Film Sodium Ion Batteries
No full textThe pulsed laser deposition was employed to produce Na2Ti6O13 (NTO) thin films, which were applied as an anode material for Sodium-Ion batteries (SIBs). X-ray diffraction made it clear that the film is crystalline in single phase. Morphology and elemental composition studies were done using FESEM. Grain size and surface roughness was measured from atomic force microscopy. The electrochemical measurements were performed at 0.5 - 3V range and it exhibited the initial discharge capacity was 49.7 mu Ah/mu m-cm(2) with coulombic efficiency 69.8%
Experimental study of surface modification in a fully turbulent Taylor-Couette flow
No full textFriction measurements were performed in a Taylor-Couette setup. Drag reduction was obtained with a riblet surface and indicated a drag reduction for a wide range of shear Reynolds numbers, with a maximum of 5.3% at Re_s=47000 (s+=14). Tomographic PIV verified that the friction coefficients are strongly related to the flow regimes and structures. The bulk fluid rotation was changed by the application of the riblets, as the wall-bounded flow conditions at the inner cylinder wall were changed due to the surface modification and is called the rotation effect. A simple model was used to indicate the averaged bulk velocity shift (1.4%), after which the drag changes due to the rotation effect (-1.9%) and the riblet effect (-3.4%) were determined. The bulk velocity shift of 1.4% was verified by PIV measurements. Compliant surfaces will be further investigated to check their required conditions for drag reduction of wall-bounded flow
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
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