170,366 research outputs found
Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint"
Müller et al. (Reports, 27 October 2006, p. 654) showed that inhibition of the gamma-tubulin ring complex (gamma-TuRC) activates the spindle assembly checkpoint (SAC), which led them to suggest that gamma-TuRC proteins play molecular roles in SAC activation. Because gamma-TuRC inhibition leads to pleiotropic spindle defects, which are well known to activate kinetochore-derived checkpoint signaling, we believe that this conclusion is premature
Le pianiste turc Fazil Say est jugé en Turquie pour blasphème
Le virtuose turc du piano Fazil Say jugé pour blasphème rejette les accusations Le pianiste turc mondialement connu et bête noire des islamistes, Fazil Say, a comparu jeudi devant un tribunal d'Istanbul où il a rejeté les accusations d'atteintes aux valeurs religieuses des musulmans, a constaté l'AFP. (c) Afp ISTANBUL (AFP) - Le pianiste turc mondialement connu et bête noire des islamistes, Fazil Say, a comparu jeudi devant un tribunal d'Istanbul où il a rejeté les accusations d'atteintes..
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
Ophthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Vocabulaire arabe-turc, en vers, composé par Ferichté Oghlou ʿAbd al-Laṭîf (فرشته اوغلى عبد اللطيف).
Numérisation effectuée à partir d'un document de substitution.Les mots les plus usités de la langue arabe s'y trouvent avec le turc à côté. Dans cet exemplaire, il y a beaucoup de notes et d'additions sur les marges et entre les lignes. La préface est en turc et commence par ces mots : حمد ثابتدر اول الله كه عالمى عُلما يله بزتدى. Ms. daté de l'an 935 (1528-1529 de J.-C.)
TECHNOLOGY ADOPTION, CAPITAL MAINTENANCE AND THE TECHNOLOGICAL GAP
We study optimal growth models à la Nelson and Phelps (1966) where labor resources can be allocated either to production, technology adoption or capital maintenance. We first characterize the balanced growth paths of a benchmark model without maintenance. Then we introduce the maintenance activity via the depreciation rate of capital. We characterize the optimal allocation of labor across the three activities. Though maintenance deepens the technological gap by diverting labor resources from adoption, we show that it generally increases the long run output level. Moreover we find that equilibrium maintenance and adoption efforts respond in opposite directions to policy or technology shocks. When a technological shock occurs, the reduction of the equilibrium technological gap is incompatible with welfare maximization. Finally, we find that the long term output response to policy shocks is slightly higher in the presence of maintenance.Adoption, Maintenance, Technological gap, Output gap
Les débuts du conflit italo-turc : octobre 1911 - janvier 1912
Allain Jean-Claude. Les débuts du conflit italo-turc : octobre 1911 - janvier 1912. In: Revue d’histoire moderne et contemporaine, tome 18 N°1, Janvier-mars 1971. pp. 106-115
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Relación entre el índice de Turc y el rendimiento de la alfalfa en la España peninsular
The modernisation of Spanish agrarian insurance demands the use of crops yield prediction models. Many yield prediction models are difficult to apply because data are not available. In this work, we studied the performance of Turc productivity index and its components to model alfalfa yields from climatic data. Data of alfalfa provincial yields from 1979 to 1995 and climatic data from 482 peninsular meteorological stations of 1966-1996 were use. Regression equations between provincial alfalfa jdeld and the Turc index and its components were obtained. A model based on seasonal dryness factors and the product of these by temperature was able to explain a large variability (87%). One component of Turc index, the annual dryness factor, explained larger variance (73%) that the Turc index per se, which confirms the importance of water deficit in Mediterranean agriculture. In conclusion, an index of easy calculation, using available climatic data and applied on provincial scale was able to estimate the vegetal mass crops in the conditions of peninsular Spain.[es] La modernización del sistema de seguros en España exige el uso de modelos de predicción de rendimientos de cosecha para el conjunto del territorio nacional. Muchos modelos de estimación de rendimientos son de difícil aplicación porque no están disponibles los datos de entrada. En este trabajo, se estudia la capacidad del índice de productividad de Ture y sus componentes para modelizar los rendimientos de la alfalfa a partir de datos climáticos. Para ello, se han usado los datos de rendimiento medio provincial de la alfalfa en secano de la serie 1979-1995 y los datos climáticos de 482 observatorios meteorológicos de la península de la serie 1966-1996. Se han obtenido las ecuaciones de regresión entre el rendimiento provincial de la alfalfa y el índice de Ture o diversos componentes del mismo. Un modelo basado en los factores estacionales de sequedad y en el producto de éstos por la temperatura explica un elevado porcentaje de varianza (87%). Un componente del índice de Ture, el factor de sequedad anual, llega a explicar más varianza (73%) que el propio índice anual de Ture, lo que confirma la importancia del déficit hídrico en la agricultura mediterránea. En definitiva, un índice sencillo de cálculo, que emplea datos climáticos fácilmente disponibles y que es aplicado a escala provincial resulta válido como estimador del rendimiento de cultivos de masa vegetal en las condiciones de la España peninsular.
[fr] La modernisation des assurances agricoles a l'Espagne exige l'usage de modèles pour prédire les rendements des récoltes dans l'ensemble du territoire national. Beaucoup de modèles d'estimation des rendements sont difficils a apliquer parce que les données nécessaires ne sont pas disponibles. Dans ce travail, on étude la capacité de l'indice de productivité de Turc et quelques de ses composantes pour modèliser les rendements de le luzerne a partir des données climatiques. Pour ceci, on a utilisé les données du rendement moyen de le luzerne dans les provinces espagnoles pour les années 1979- 1995 et les données de 482 observatoires météorologiques pour les années 1966-1996. On a obtenu les équations de regresion entre le rendement provincial de le luzerne et l'indice de Turc ou quelques de ses composantes. Un modèle basé aux facteurs saisonniers de sécheresse et le produit de ceux facteurs pour la température explique un pourcentage de la variance élevé (87%). Une composante de l'indice de Turc, le facteur de sécheresse annual, explique plus de variance (73%) que l'indice de Turc annual, ce qui confirm l'importance du déficit de l'eau a l'agriculture méditerranéenne. En conclusion, un indice simple à calculer, qui emploi des données climatiques facilement atteints et qui est apliqué a niveau provincial, succède a être un prédicteur appropié du rendement des récoltes a masse végétale pour les conditions de l'Espagne péninsulaire
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
We create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
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