50 research outputs found
INFLUENCE OF CORONARY PERFUSION ON THE RELATIONSHIP BETWEEN DIASTOLIC PRESSURE AND LEFT-VENTRICULAR VOLUME
No full textINFLUENCE OF CORONARY PERFUSION ON THE RELATIONSHIP BETWEEN DIASTOLIC PRESSURE AND LEFT-VENTRICULAR VOLUME
No full textUNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO,FAC MED BOTUCATU,DEPT CLIN MED,BOTUCATU,SP,BRAZILUNIV ESTADUAL PAULISTA JULIO MESQUITA FILHO,FAC MED BOTUCATU,DEPT CLIN MED,BOTUCATU,SP,BRAZI
Isoproterenol-induced hypertrophy may result in distinct left ventricular changes
No full text1. the aim of the present study was to analyse the possible lack of uniformity in isoproterenol (ISO)-induced myocardial hypertrophy.2. Data obtained for isovolumic hearts isolated from 20 rats treated with ISO (0.3 mg/kg over 8 days) were divided into two groups (H-1, n=10; H-2, n = 10) according to the volume (mean +/- SD) needed to change left ventricle diastolic pressure front 0 to 40 mmHg (H-1, 181 +/- 30 mu L; H-2, 108 +/- 14 mu L). Eight control rats (C; 165 +/- 37 mu L) were used for comparison.3. in addition to ventricular distensibility differences, the groups differed in terms of myocardial mass (mean +/- SEM: HI, 181 +/- 3 mg > H-2, 166 +/- 3 mg > C, 136 +/- 3 mg; P H-1, 28 +/- 2 msec; P = 0.0012) and of maximum developed circumferential stress (C, 145 +/- 9 kdyn/cm(2) = H-1, 137 +/- 6 kdynlcm' > H-2, 110 +/- 4 kdyn/cm(2); P = 0.002).4. Our results show that ISO-induced myocardial hypertrophy is not homogeneous. Data obtained for H-2, taken as a whole and compared with H-1 (smaller myocardial mass and impairment of relaxation, elastic stiffness and force generation), suggest that, in some animals, myocardial necrosis and reparative fibrosis may prevail over the stimulus for myocyte growth. the lack of uniformity of ISO-induced myocardial hypertrophy has not been previously reported and may have contributed to the divergence observed in the literature regarding the functional characteristics of the present model.Universidade Federal de São Paulo, Dept Physiol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Physiol, São Paulo, BrazilWeb of Scienc
THE ABSENCE OF THE DESCENDING-LIMB OF THE FRANK-STARLING CURVE OF THE DEPRESSED GUINEA-PIG WHOLE VENTRICLE
No full textLinking person job fit to employee job performance amid employees of services sector: The role of burnout as mediator
No full textAbstract. Person Job Fit (PJF) and Employee Job Performance (EJP) are general issues in now a days in business world. Most of the individuals alter their job due to misfit with their occupation which disturbs their job performance. Misfit can be a reasonable predictor of incompatibility between PJF and EJP. It can aggravate feeling on job and personal well-being of employees. Usually the employees who are better fit with their jobs are more satisfied, they can increase their job performance and produce good results. To contest with this we presume through watchful consideration to PJF through assessment phase or consultation, the organizations may hire those employees who are able to bring change and easily adjust in the environment and can avoid the adverse effects of burnout which is caused by incompatibility of individual’s job. The aim of present research work is to observe the detailed effects of EJP and significance of PJF in order to enable organization to avoid from unusual cost of personnel who are incompatible to their jobs. The studies designate that the employees who are compatible with their jobs may have a greater efficiency and are able to make changes smoothly in organization than those employees who are misfit with their jobs. This study also aim to examine if Burnout (BO) mediate relationships between PJF and EJP. Current study’s findings demonstrates that by giving proper attention to PJF in organization are indispensable facets for declining burnout.Keywords. Person job fit, Employee job performance and Burnout.JEL. D91, J24, J28, O14, Z22
THE ABSENCE OF THE DESCENDING-LIMB OF THE FRANK-STARLING CURVE OF THE DEPRESSED GUINEA-PIG WHOLE VENTRICLE
No full textUNIV ESTADUAL CAMPINAS,INST BIOL,DEPT FIS,BR-13100 CAMPINAS,SP,BRAZILUNIV ESTADUAL PAULISTA,INST BASICO BIOL MED & AGR,DEPT ESTATIST,BR-18610 BOTUCATU,SP,BRAZILUNIV ESTADUAL PAULISTA,INST BASICO BIOL MED & AGR,DEPT ESTATIST,BR-18610 BOTUCATU,SP,BRAZI
THE ABSENCE OF THE DESCENDING-LIMB OF THE FRANK-STARLING CURVE OF THE DEPRESSED GUINEA-PIG WHOLE VENTRICLE
No full text17212913
THE ABSENCE OF THE DESCENDING-LIMB OF THE FRANK-STARLING CURVE OF THE DEPRESSED GUINEA-PIG WHOLE VENTRICLE
No full textLEFT-VENTRICULAR MASS ESTIMATED BY M-MODE ECHOCARDIOGRAM IS NOT ALTERED BY CHANGES IN CARDIAC SHAPE AND DIMENSIONS DUE TO ACUTE ARTERIAL-HYPERTENSION
No full textThe effect of changes in left ventricular (LV) shape and dimensions due to acute arterial hypertension induced by mechanical obstruction of the aorta for 10 min on LV mass values estimated by M-mode echocardiogram was studied in 14 anesthetized dogs. Although the systolic pressure increased from 117.5 +/- 19.9 to 175.4 +/- 22.9 mmHg altered ventricular diameter from 2.77 +/- 0.49 cm to 3.17 +/- 0.67 cm (P<0.05) and wall thickness from 0.83 +/- 0.09 to 0.75 +/- 0.09 cm (P<0.05), LV mass estimated before (73.5 +/- 19.1 g) and after (78.3 +/- 26.4 g) hypertension was not significantly different. We demonstrate here for the first time that changes in LV dimensions induced by acute arterial hypertension do not modify LV mass values estimated by the M-mode electrocardiogram method
CHARACTERISTICS OF ARTERIAL-HYPERTENSION IN RESPONSE TO BOLUS INJECTION OF PHENYLEPHRINE IN ATROPINIZED PATIENTS
No full textThe changes of arterial pressure promoted by bolus injection of 50 mg phenylephrine (PHE) were studied in 20 atropinized patients (5 normal subjects, 13 patients with mitral valve disease, 1 patient with essential arterial hypertension and 1 patient with hypertrophic cardiomyopathy) submitted to routine catheterism. Patients with aortic valve disease, left ventricular outflow tract obstruction and intracardiac shunt were excluded from the study. All patients were in sinus rhythm, without heart failure. Arterial pressure started to increase at 14.8 +/- 5.4 s (range, 5.6 to 27 s; mean +/- SD) after PHE. There was an increase of 37.8 +/- 16.7 mmHg (range, 12.5 to 70 mmHg) in systolic pressure and of 26.6 +/- 11.1 mmHg (range, 7.5 to 42.5 mmHg) in diastolic pressure. Peak hypertension was attained at 36.6 +/- 16.4 s (range, 10.8 to 64.9 s) and hypertension continued for 176 +/- 92 s (range, 11 to 365 s). Heart rate was 114 +/- 21 bpm before PHE and 111 +/- 21 bpm (P<0.05) after PHE. There were no adverse events associated with intravenous PHE injection in any patient, in accordance with the general view that bolus injection of PHE is a safe and practical maneuver to promote arterial hypertension
