1,721,133 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    A Novel Steerable Catheter Controlled with a Biohybrid Actuator: A Feasibility Study

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    Targeted therapies allow increasing the efficacy of treatments for several diseases, including cancer. The release of drugs or chemicals directly in the site of interest will be beneficial for maximizing the therapy and minimize side effects. Here, we report the concept and a preliminary analysis of an innovative intravascular steerable catheter guided by an on-board biohybrid actuator, aiming to release drugs into deep and tortuous regions within the cardiovascular systems. The catheter performance has been estimated through analytical and numerical analyses, varying catheter diameter, wall thickness, and actuator force. Results show how larger catheter deflections can be obtained with a smaller outer diameter and decreasing wall thickness. Besides, improved outcomes can be achieved by applying the biohybrid actuator distant from the catheter tip extremity and maximizing the magnitude of the applied forces. Despite the need to further improve the performance of this concept (e.g., by decreasing material stiffness), these preliminary results show great promise in view of future experimentation of such kind of actuation to drive microcatheters through the cardiovascular network

    Injectable gelatin-based photocurable fiber-reinforced hydrogel for the treatment of osteochondral defects

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    Osteochondral defects are one of the most motor-disabling conditions worldwide. A limited intrinsic regenerative capability features cartilage and bone tissues involved in large osteochondral lesions and, to date, there is no clinical treatment capable of appropriately restoring them. We report an innovative injectable composite hydrogel based on gelatin methacryloyl (GelMA) loaded with dispersed fibers made of a blend polycaprolactone (PCL)/GelMA. The fibers were produced by electrospinning, and cut in stripes using a cryostat-based cutting approach. Their embodiment in the GelMA matrix improved the compressive mechanical properties of the pristine GelMA hydrogel. Specific conditions (needle size: 18G and 20G; temperature: 30 and 37°C) were found compatible with the injection of the composite hydrogel, before crosslinking, matching the criteria reported in EN ISO 7886 1:2018 standard. These preliminary results are promising in view of the optimization of injectable reinforced GelMA-based formulations to be used for the treatment of osteochondral injuries

    Injectable gelatin-based photocurable fiber-reinforced hydrogel for the treatment of osteochondral defects

    No full text
    Osteochondral defects are one of the most motor-disabling conditions worldwide. A limited intrinsic regenerative capability features cartilage and bone tissues involved in large osteochondral lesions and, to date, there is no clinical treatment capable of appropriately restoring them. We report an innovative injectable composite hydrogel based on gelatin methacryloyl (GelMA) loaded with dispersed fibers made of a blend polycaprolactone (PCL)/GelMA. The fibers were produced by electrospinning, and cut in stripes using a cryostat-based cutting approach. Their embodiment in the GelMA matrix improved the compressive mechanical properties of the pristine GelMA hydrogel. Specific conditions (needle size: 18G and 20G; temperature: 30 and 37°C) were found compatible with the injection of the composite hydrogel, before crosslinking, matching the criteria reported in EN ISO 7886 1:2018 standard. These preliminary results are promising in view of the optimization of injectable reinforced GelMA-based formulations to be used for the treatment of osteochondral injuries

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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