1,720,990 research outputs found
Electrospun nanomaterials implementing antibacterial inorganic nanophases
Full text linkElectrospinning is a versatile, simple, and low cost process for the controlled production of fibers. In recent years, its application to the development of multifunctional materials has encountered increasing success. In this paper, we briefly overview the general aspects of electrospinning and then we focus on the implementation of inorganic nanoantimicrobials, e.g., nanosized antimicrobial agents in electrospun fibers. The most relevant characteristics sought in nanoantimicrobials supported on (or dispersed into) polymeric materials are concisely discussed as well. The interesting literature issued in the last decade in the field of antimicrobial electrospun nanomaterials is critically described. A classification of the most relevant studies as a function of the different approaches chosen for incorporating nanoantimicrobials in the final material is also provided
MESNA for chemically assisted tissue dissection
No full textImportance of the field: To date, surgical dissection is based only on mechanical forces. The use of a chemical product that is able to ease tissue dissection represents an important advance. MESNA (sodium-2- mercaptoethanesulfonate) has recently been validated for chemically assisted tissue dissection during surgery or invasive procedures. No other drugs are available for this. Areas covered in this review: An extensive literature search was conducted that included published articles and abstracts on the use of MESNA during surgery or invasive procedures in the experimental and clinical setting, since 1997. Clinically validated settings are ear, nose and throat (ENT), gynecological and orthopedic fields. What the reader will gain: A state-of-the-art overview of intraoperative applications of MESNA, and a consideration of the possible mechanisms underlying chemically assisted tissue dissection. Take home message: MESNA has been successfully used to ease abdominal myomectomies and excision of endometrial cysts; in ENT surgery, topical MESNA could be widely used, from ear and skull base to head and neck diseases, in both outpatient and operating-room settings. In revision lumbar spine surgery, its use resulted in significantly easier surgery and reduction of postoperative complications. Given the high efficacy and favorable complications rate, future applications in the surgical field are expected to increase. © 2010 Informa UK Ltd
Electrospun scaffolds for bone tissue engineering
No full textTissue engineering aims to regenerate native tissues and will represent the alternative choice of standard surgery for different kind of tissue damages. The fundamental basis of tissue engineering is the appropriate selection of scaffolds and their morphological, mechanical, chemical, and biomimetic properties, closely related to cell lines that will be seeded therein. The aim of this review is to summarize and report the innovative scientific contributions published in the field of orthopedic tissue engineering, in particular about bone tissue engineering. We have focused our attention on the electrospinning technique, as a scaffold fabrication method. Electrospun materials are being evaluated as scaffolds for bone tissue engineering, and the results of all these studies clearly indicate that they represent suitable potential substrates for cell-based technologies. © 2011 Springer-Verla
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Pluronic F127 hydrogel characterization and biofabrication in cellularized constructs for tissue engineering applications
Full text linkA new method for printing cellularised scaffolds from thermosensitive hydrogels was here proposed. Pluronic F127 solutions and hydrogels in water-based media (15-40%w/v) were investigated by rheological analysis and tube inverting test. Pluronic F127 hydrogel with 25%w/v concentration was selected as bioink due to its fast gelation at 37°C (5min), suitable viscoelastic properties (G’= 16500Pa at 37°C), pseudoplastic behaviour and fast viscosity recovery after shearing (approximately 5 s). Not cellularised and cellularised (with Balb/3T3 fibroblasts) scaffolds with a 0°/90° pattern were fabricated by additive manufacturing technique. Cells were well distributed along scaffold filaments and cell viability was preserved during printing
Metodo per la preparazione di costrutti cellularizzati a base di idrogeli termosensibili
No full text- …
