87,997 research outputs found
Universality of anisotropic fluctuations from numerical simulations of turbulent flows
No full textWe present new results from a direct numerical simulation of a three-dimensional homogeneous Rayleigh-Bénard system (HRB), i.e. a convective cell with an imposed linear mean temperature profile along the vertical direction. We measure the SO(3)-decomposition of both velocity structure functions and buoyancy terms. We give a dimensional prediction for the values of the anisotropic scaling exponents in this Rayleigh-Bénard systems. Measured scaling does not follow dimensional estimate, while a better agreement can be found with the anisotropic scaling of a different system, the random-Kolmogorov-flow (RKF) (BIFERALE L., DAUMONT I., LANOTTE A. and TOSCHI P., Phys. Rev. E, 66 (2002) 056306). Our findings support the conclusion that scaling properties of anisotropic fluctuations are universal, i.e. independent of the forcing mechanism sustaining the turbulent flow
Universality of anisotropic fluctuations from numerical simulations of turbulent flows
No full textWe present new results from a direct numerical simulation of a three-dimensional
homogeneous Rayleigh-B´enard system (HRB), i.e. a convective cell with an imposed linear mean temperature profile along the vertical direction. We measure the SO(3)-decomposition of both velocity structure functions and buoyancy terms. We give a dimensional prediction for the values of the anisotropic scaling exponents in this Rayleigh-B´enard systems. Measured scaling does not follow dimensional estimate, while a better agreement can be found with the anisotropic scaling of a different system, the random-Kolmogorov-flow (RKF) (Biferale L., Daumont I., Lanotte A. and Toschi F., Phys. Rev. E, 66 (2002) 056306). Our findings support the conclusion that scaling properties of anisotropic fluctuations are universal, i.e. independent of the forcing mechanism sustaining the turbulent flow
Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC).
No full textMetro G, Finocchiaro G, Toschi L, Bartolini S, Magrini E, Cancellieri A, Trisolini R, Castaldini L, Tallini G, Crino' L, Cappuzzo F. Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC). Reviews on recent clinical trials. 2006;1:1-13
Joint statistics of acceleration and vorticity in fully developed turbulence
No full textWe report results from a high-resolution numerical study of fluid particles transported by a fully developed turbulent flow at R¿ = 280. Single-particle trajectories were followed for a time range spanning more than three decades, from less than a tenth of the Kolmogorov timescale up to one large-eddy turnover time. We present results concerning acceleration statistics and the statistics of trapping by vortex filaments conditioned to the local values of vorticity and enstrophy. We found that a suitable observable, a¿ = a v, connected to the centripetal acceleration, is strongly sensitive to the trapping of particles into vortex filaments. In particular, we found that its sign may persist up to 10-15 t¿, while the typical oscillation of the longitudinal acceleration happens on a time lag of a few t¿
Effect of lycopene supplementation on semen quality and reproductive performance in rabbit
Full text link[EN] A total of 18 hybrid strain Martini male rabbits were randomly divided into three experimental groups. The animals in the first and second groups drank water with 0.1 and 0.5 g/l of lycopene addition (B and C groups, respectively), while water without any supplement was administered to the control group rabbits (A group) for 8 weeks. Semen was collected from 18 bucks (6 animals/group) for 5 consecutive weeks. Ejaculate volume was determined by graduated test tube and sperm concentration was calculated by Neubauer chamber. Sperm motility was evaluated subjectively by a phase contrast microscope and forward progressive motility (FPM) scored 1¿4 (low-high). Sperm viability was assessed by nigrosin/eosin (N/E) staining procedure. At the end of the semen evaluation period, 20 females per group were inseminated on day 11 post partum with a pool of semen collected from each experimental group. Data showed that the highest level of lycopene (C group) resulted in a significantly greater volume of ejaculate and total number of sperm than in the control group (0.98 vs. 0.78 ml and 364 vs. 227, P0.05). This study shows the positive effects of lycopene supplementation on semen production and refrigerated semen characteristics. Lycopene supplementation of drinking water could have interesting applications in field conditions, although further research into the role of this antioxidant in animal production is needed.Mangiagalli, M.; Cesari, V.; Cerolini, S.; Luzi, F.; Toschi, I. (2012). Effect of lycopene supplementation on semen quality and reproductive performance in rabbit. World Rabbit Science. 20(3):141-148. https://doi.org/10.4995/wrs.2012.1150SWORD14114820
Preparazione di materiali nanocompositi a base carbonio per applicazioni tecnologiche
Full text linkLa sintesi e le applicazioni dei materiali nanocompositi sono di importanza strategica nel campo della scienza dei materiali. In questo lavoro di tesi sono stati sviluppati diverse tipologie di materiali nanocampositi: Resina epossidica/nanotubi di carbonio (CNT), Poli(3,4-etilendiossitiofene) polistirensulfonato (PEDOT:PSS)/CNT, metallo/CNT. Questi materiali sono stati caratterizzati con le seguenti tecniche: Microscopia elettronica a scansione (SEM), Microscopia a forza atomica (AFM), microscopia acustica a forza atomica (AFAM), spettroscopia Raman e tecniche elettroanalitiche. La caratterizzazione funzionale è stata condotta testando i materiali in differenti applicazioni: Sensori resistivi, sensori di tipo nano-bilancia al quarzo e gestione del calore. I risultati sperimentali sono riportati nel lavoro di tesi.The synthesis and applications of nanocomposites are an important and strategical field of nanomaterial science. In this work has been developed several kind of nanocomposit materials, in particular: Epoxy resins and carbon nanotubes (CNT), Poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT:PSS) and CNT, metal and CNT. This material has been characterized by means of: scanning electron microscopy (SEM), Atomic force miscroscpy (AFM), acoustic atomic force microscopy (AFAM), Raman spectroscopy and Electroanalitical techniques. The developed nanocomposite material has been tested by means different kind of application: Resistive sensors, quartz nano-balance and thermal management. The results are reported in the thesis work
The impact of public funding on science valorisation: an analysis of the ERC Proof-of-Concept Programme
Full text linkGovernments and public agencies are increasingly keen to support the translation of scientific discoveries into commercial and societal applications through science valorisation funding, as a way to enhance progress and inclusive growth. In this paper, we use grant-level data from the European Research Council Proof-of-Concept (PoC) programme, in order to assess the impact of public funding on a broad set of science valorisation outcomes, including licensing, spinoff formation, R&D collaborations, consulting and access to follow-on funding. We employ an instrumental variable approach to compare the valorisation outcomes of projects that obtained an ERC PoC grant to a group of projects that applied to the PoC scheme but were not funded. We find that the programme was effective in fostering the early valorisation of scientific discoveries by all measures of success that we employed. Overall, thus, our findings speak in favour of this type of policy instrument as a catalyst to accelerate the transition of scientific breakthroughs towards practical applications
Do venture capitalists have a bias against investment in academic spinoffs? Evidence from the micro and nanotechnology sector in the UK
No full textWe provide empirical evidence to resolve the dilemma about the existence of a VCs’ bias against investments in academic spin-offs. We also investigate the nature of university spin-offs to capture the heterogeneity at the base of differences in their ability to attract VC funding. Finally, we examine whether their valuation varies between private and public VC firms. Our results on a sample of 247 spin-offs in the micro and nanotechnology sector in the UK reject the presence of the bias, highlighting the importance of the IPRs and the university’s scientific prestige in the academic spin-off’s ability to access to VC financing. Also, different investing behaviours are pointed out among VCs, with a stronger attention given by private VCs to the benefits deriving from academic-industrial collaborations
The intersection between capacity building and finance in M. Granieri, A. Basso Capacity Building in Technology Transfer – The European Experience
No full textNew ventures do not have access to the same financial resources as larger firms, for the presence of the so-called “funding gap”. Such a barrier can be particularly pronounced for university startups, given their knowledge- and technology-based nature. To address this market failure, universities (often in collaboration with public and/or private partners) have started to activate programs to support their startups. By presenting a set of best practices and case studies, the chapter describes three main areas of intervention in the area of capacity building for accessing finance: (i) raising awareness and competences to access external finance (i.e. training activities and commercialization boot- camps), (ii) supporting the validation and maturation of university technologies (i.e. proof-of-concept programmes and university accelerator programmes) and (iii) enhancing interactions and building partnership with investors (i.e. matchmaking events with investors, networks of different types of investors, formalized partnerships between universities and financial investors, and university seed funds)
Dall’arte al folklore: il caso di Paolo Toschi tra ricerca di riconoscimento e fascismo
No full textIl saggio, già apparso nella rivista Lares nel 2021 e qui riprodotto con alcune lievi modifiche. analizza il percorso intellettuale e professionale di Paolo Toschi durante il fascismo. Come molti altri della sua generazione, Toschi si trovò a simpatizzare con il fascismo sulla scia dell’esperienza della Prima Guerra mondiale e nel nome della difesa dei valori tradizionali. Toschi fu comunque sempre attratto più dall’arte e dalla cultura che dall’impegno politico attivo. Come altri intellettuali della sua generazione egli soffrì anche la difficoltà di un inserimento professionale soddisfacente che cercò di compensare con la collaborazione con giornali e riviste e con l’impiego delle relazioni derivato dall’inserimento nelle istituzioni culturali fasciste.The essay, which already appeared in the peer review Journal Lares in 2021 and is reproduced here with some slight modifications, analyses Paolo Toschi’s intellectual and professional career during fascism. Like many others of his generation, Toschi found himself sympathising with fascism in the wake of the First World War experience and in the name of defending traditional values. However, Toschi was always more attracted to art and culture than to active political engagement. Like other intellectuals of his generation, he also suffered from the difficulty of a satisfactory professional placement, which he tried to compensate for by collaborating with newspapers and magazines and by using the relationships derived from his inclusion in Fascist cultural institutions
- …
