367 research outputs found
Study of Optimal Perimetric Testing In Children (OPTIC): Normative visual field values in children
No full textPurpose: We sought to define normative visual field (VF) values for children using common clinical test protocols for kinetic and static perimetry. Design: Prospective, observational study. Subjects: We recruited 154 children aged 5 to 15 years without any ophthalmic condition that would affect the VF (controls) from pediatric clinics at Moorfields Eye Hospital. Methods: Children performed perimetric assessments in a randomized order using Goldmann and Octopus kinetic perimetry, and Humphrey static perimetry (Swedish Interactive Thresholding Algorithm [SITA] 24-2 FAST), in a single sitting, using standardized clinical protocols, with assessment by a single examiner. Unreliable results (assessed qualitatively) were excluded from the normative data analysis. Linear, piecewise, and quantile mixed-effects regression models were used. We developed a method to display age-specific normative isopters graphically on a VF plot to aid interpretation. Main Outcome Measures: Summary measures and graphical plots describing normative VF data for 3 common perimetric tests. Results: Visual field area increased with age on testing with Goldmann isopters III4e, I4e, and I2e (linear regression; P < 0.001) and for Octopus isopters III4e and I4e (linear regression; P < 0.005). Visual field development occurs predominately in the infero-temporal field. Humphrey mean deviation (MD) showed an increase of 0.3 decibels (dB; 95% CI, 0.21-0.40) MD per year up to 12 years of age, when adult MD values were reached and thereafter maintained. Conclusions: Visual field size and sensitivity increase with age in patterns that are specific to the perimetric approach used. These developmental changes should be accounted for when interpreting perimetric test results in children, particularly when monitoring change over time
Communication, reception and possible consciousness - the contribution of Lucien Goldmann
No full textO presente texto resgata criticamente a contribuição de Lucien Goldmann no âmbito da comunicação apontando em especial para o nexo entre recepção e política no contexto do pensamento do mesmo autor. This paper critically rescues Lucien Goldmann\u27s contribution to the field of communication. His intention is pointing in particular to the nexus between politics and reception in the context of the work of this author
Regulation pro-/antiinflammatorischer Faktoren in Chlamydia pneumoniae-infizierten Alveolarmakrophagen und Monozyten gesunder rauchender Probanden
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Charakterisierung inflammatorischer Vorgänge im induzierten Sputum bei COPD unter besonderer Berücksichtigung des Einflusses von Dithiothreitol
No full textFunctional studies on the initial phase of mycobacterial infections in human lung tissues
No full textSystematic investigation of lipid profiles from human lung tissues reveals specific lipidome alterations in lung cancer and pulmonary emphysema
No full textUntersuchungen zum TGF?-Signalweg bei Lungenerkrankungen unter besonderer Berücksichtigung des Pseudorezeptors BAMBI
No full textBedeutung der Gene des Proteasoms und des Rel/Nuclear factor U+03BAB-Systems für den Herzinfarkt
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