27 research outputs found
Gerty Cori to Viktor Hamburger, July 1, 1944
No full textHandwritten letter, 2 pagessigned 'Gerty'-author is most likely Gerty CoriCorrespondenc
Gerty Cori to Viktor Hamburger, August 19, 1946
No full textHandwritten letter, 2 pagessigned 'Gerty'-author is most likely Gerty CoriCorrespondenc
Gerty Cori to Viktor Hamburger, August 19, 1948
No full textHandwritten letter, 2 pagesletter continued on back page, signed 'Gerty'- author is most likely Gerty CoriCorrespondenc
The influence of genetic variation in thirty selected genes on the clinical characteristics of early onset breast cancer
No full textIntroduction: common variants that alter breast cancer risk are being discovered. Here, we determine how these variants influence breast cancer prognosis, risk and tumour characteristics.Methods: we selected 1,001 women with early onset nonfamilial invasive breast cancer from the Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH) cohort and genotyped 206 single nucleotide polymorphisms (SNPs) across 30 candidate genes. After quality control, 899 cases and 133 SNPs remained. Survival analyses were used to identify SNPs associated with prognosis and determine their interdependency with recognized prognostic factors. To identify SNPs that alter breast cancer risk, association tests were used to compare cases with controls from the Wellcome Trust Case Control Consortium. To search for SNPs affecting tumour biology, cases were stratified into subgroups according to oestrogen receptor (ER) status and grade and tested for association.Results: we confirmed previous associations between increased breast cancer risk and SNPs in CASP8, TOX3 (previously known as TNRC9) and ESR1. Analysis of prognosis identified eight SNPs in six genes (MAP3K1, DAPK1, LSP1, MMP7, TOX3 and ESR1) and one region without genes on 8q24 that are associated with survival. For MMP7, TOX3 and MAP3K1 the effects on survival are independent of the main recognized clinical prognostic factors. The SNP in 8q24 is more weakly associated with independent effects on survival. Once grade and pathological nodal status (pN stage) were taken into account, SNPs in ESR1 and LSP1 showed no independent survival difference, whereas the effects of the DAPK1 SNP were removed when correcting for ER status. Interestingly, effects on survival for SNPs in ESR1 were most significant when only ER-positive tumours were examined. Stratifying POSH cases by tumour characteristics identified SNPs in FGFR2 and TOX3 associated with ER-positive disease and SNPs in ATM associated with ER-negative disease.Conclusions: we have demonstrated that several SNPs are associated with survival. In some cases this appears to be due to an effect on tumour characteristics known to have a bearing on prognosis; in other cases the effect appears to be independent of these prognostic factors. These findings require validatation by further studies in similar patient group
Translation and translatological analysis of an excerpt from Kateřina Tučková's novel “Vyhnání Gerty Schnirch”
No full textOvaj diplomski rad temelji se na prijevodu ulomka romana Progonstvo Gerte Schnirch (Vyhnání Gerty Schnirch) češke suvremene autorice Kateřine Tučkove s češkog na hrvatski jezik i njegovoj translatološkoj analizi. U prvom dijelu rada najprije su predstavljeni život i stvaralaštvo Kateřine Tučkove te roman Progonstvo Gerte Schnirch koji tematizira češko-njemačke odnose neposredno prije, za vrijeme te u razdoblju nakon Drugog svjetskog rata kroz sudbinu glavne junakinje Gerte Schnirch. Nakon toga je uslijedio kratak pregled češko-njemačkih odnosa kroz povijest i prikaz društveno-političke pozadine romana. U drugom dijelu rada nalazi se prijevod ulomka romana zajedno s originalom na češkom jeziku. Treći dio rada posvećen je translatološkoj analizi prevedenog ulomka, u sklopu koje su prikazani i objašnjeni odabrani prevoditeljski postupci i metode s fokusom na prevođenje nepodudarnih kulturnih elemenata i nepodudarnosti između jezičnih sustava.This thesis is based on the translation of an excerpt from the novel The Expulsion of Gerta Schnirch (Vyhnání Gerty Schnirch) by the Czech contemporary author Kateřina Tučková from Czech into Croatian language and its translatological analysis. The first part of the thesis presents the life and work of Kateřina Tučková and the novel The Expulsion of Gerta Schnirch, which deals with Czech-German relations just before, during and after the World War II through the fate of the main character Gerta Schnirch. This was followed by a brief overview of the history of Czech-German relations and a depiction of the socio-historical context of the novel. The second part of the thesis contains a translation of the Czech excerpt into Croatian and the Czech original. The third part of the thesis is dedicated to the translatological analysis of the translated excerpt, which presents and explains selected translation procedures and methods focusing on the translation of cultural and linguistic differences.Tato diplomová práce se zabývá překladem úryvku z románu Vyhnání Gerty Schnirch české současné autorky Kateřiny Tučkové z češtiny do chorvatštiny a translatologickou analýzou přeloženého textu. První část práce je nejprve věnovaná životu a tvorbě Kateřiny Tučkové a románu Vyhnání Gerty Schnirch, který pojednává o česko-německých vztazích těsně před, během a po druhé světové válce prostřednictvím osudu titulní hrdinky Gerty Schnirch. Poté následoval stručný přehled dějin česko-německých vztahů a zobrazení společensko-historického kontextu románu. Druhá část práce obsahuje překlad úryvku do chorvatštiny a český originál. Třetí část práce přináší translatologickou analýzu přeloženého úryvku ve které jsou analyzovány a zdůvodněny překladatelské postupy a metody se zaměřením na překlad kulturních a jazykových odlišností
Lost in Consumerism: Existential and Linguistic Wanderings in Confusion d’instants (2003) by Gerty Dambury
No full textGuadeloupean author Gerty Dambury’s play Confusion d’instants (2003) is a treatment of the impact of globalization on the French and French Caribbean societies’ most disenfranchised members. It also explores the interaction of personal and collective memory with local, national, and global histories. Confusion d’instants depicts the lives of three characters belonging to different generations and genders, who each speak in a single tense (past, present, or future). Each character also has a personal fixation with specific objects of consumption, such as radios, cars, or household appliances. Through the experiences of these socially and culturally marginalized characters Dambury articulates a searing critique of contemporary Guadeloupean society and of global capitalist consumerism in general. Through a close reading of the play, the article will analyse Dambury’s dramatic reflection on globalization, forgotten histories, and social marginalization
Lost in consumerism : existential and linguistic wanderings in Confusions d’instants (2003) by Gerty Dambury
No full textGuadeloupean author Gerty Dambury’s play Confusion d’instants (2003) is a treatment of the impact of globalization on the French and French Caribbean societies’ most disenfranchised members. It also explores the interaction of personal and collective memory with local, national, and global histories. Confusion d’instants depicts the lives of three characters belonging to different generations and genders, who each speak in a single tense (past, present, or future). Each character also has a personal fixation with specific objects of consumption, such as radios, cars, or household appliances. Through the experiences of these socially and culturally marginalized characters Dambury articulates a searing critique of contemporary Guadeloupean society and of global capitalist consumerism in general. Through a close reading of the play, the article will analyse Dambury’s dramatic reflection on globalization, forgotten histories, and social marginalization.Peer reviewe
Strategic analysis in ltd Muraka Farm
No full textBakalaureusetöö on suunatud piimatootmisega tegeleva ettevõtte strateegilisele
analüüsile. Praegune piimandussektori olukord on väga halb, kuna toorpiima hind on väga
madal ning see raskendab piimatootjate olukorda. Töö eesmärgiks on leida OÜ Muraka
Farmi ettevõttesisesed tugevused, nõrkused, võimalused ja ohtu kujutavad tegurid. Antud
ettevõtte puhul ei ole varasemalt teadlikult uuritud majanduslikkuseisu ja konkurente.
Kvantitatiivseks analüüsiks on uuritud majandusaasta aruannete erinevaid arvnäitajaid.
Kvalitatiivseks osaks on autori läbi viidud intervjuu ettevõtte juhiga. Töö käigus selgus, et
strateegiline analüüs on ettevõttes väga oluline, kuna aitab leida arendamist vajavad
valdkonnad. Läbi viidi erinevaid meetodeid, hindamaks ettevõtte seisundit. Ettevõttel on
väga palju positiivseid külgi, samas on ka nõrku külgi, mis vajavad tähelepanu. Positiivse
küljena toob autor välja isikliku tehnika olemasolu, kuna on võimalus teha sööta enda
loomadele ning pakkuda siloteenust. Negatiivseks küljeks on väike piimatoodang lehma
kohta, mis jääb Eesti keskmisele alla. Praeguse piimahinna juures ei soovita autor
piimakarja suurendada, küll aga näeb sellest põhjust olukorra paranedes, kuna see annab
võimaluse toodangut suurendada ja rohkem müüa.This bachelor’s thesis addresses a strategic analysis of a milk producing company. The
current situation in dairy farming is really bad, as the price of milk is low and it puts
businesses in a difficult position. The purpose of the thesis is to draw up a strategic
analysis of Muraka Farm Ltd to evaluate the company’s financial condition and
performance, to find opportunities for effective production systems, and to identify and
analyse its key competitors. Also, to find out the strengths and weaknesses of the company,
draw some conclusions, and to provide suggestions for improving its business efficiency.
Muraka Farm Ltd has not been so thoroughly analysed before. The quantitative analysis of
the thesis examines the figures of the annual reports of the company. The qualitative
analysis consists of an interview with the managing director. The strategic analysis of the
company appears to be highly significant, as it helps to find out which directions should be
developed. Different methods were used during the evaluation process. It appeared that the
company has a lot of positive attributes. On the other hand, there are some weaknesses that
need to be dealt with. The positive characteristic is that the company has its own
production machinery. It is possible to provide forage to the company’s cattle and offer a
service of silage making to other businesses. In addition, the company has land property,
so it does not have to spend its finances on rent. The biggest drawback is that the cows of
Muraka Farm Ldt produce 2,000 kg less milk per cow, compared with the average milk
yield per cow in Estonia. Therefore, the author of the thesis suggests investing in buildings
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and machinery, which would provide better conditions for the cattle and improve the
productivity of the company. It is not recommended to enlarge dairy cattle at current prices
for milk. The author of the thesis suggests waiting until the lowest point in dairy farming
has passed and the economic conditions have improved
Implementation analysis of a quality management system in Amello Raamatupidamisteenused OÜ
No full textMagistritöö
Ökonoomika ja ettevõtlus õppekavalToodete ja teenuse pakkujaid on aina rohkem ja konkurents muutunud tihedamaks. Kvaliteet on
oluliseks võtmeteguriks nii teenuse müümisel kui ka ettevõtte maine kujundamisel. Selleks on
vajalik luua hästitoimiv kvaliteedijuhtimissüsteem, leida pädevad töötajad ja sobivad partnerid,
kellega koostöö sujuks. Uurimisobjektiks oli väikeettevõte Amello Raamatupidamisteenused
OÜ, kus ei ole kvaliteedijuhtimissüsteemi varem uuritud ega teadlikult rakendatud. Töö
eesmärgiks oli analüüsida kvaliteedijuhtimissüsteemi rakendamist uuritavas ettevõttes ja
analüüsile tuginedes välja tuua parendamist vajavad valdkonnad. Autor kasutas
uurimismeetodina poolstruktureeritud intervjuud ettevõtte juhiga ja tarkvara juhtivspetsialistiga
ning viis läbi dokumendianalüüsi. Analüüsist selgus, et uuritavas ettevõttes ei ole
kvaliteedijuhtimissüsteemi dokumenteeritud, kuid tegevused on struktureeritud ja paigas.
Ettevõttes on reeglistik, põhimõtted ja tegeletakse protsesside kirjeldusega. ISO nõuetele
vastavust esines, kuid mitte nii detailselt kui ISO seda nõuab. Puuduseid esinesid
dokumentatsioonis, mis sisaldas vananenud infot. Analüüsile tuginedes tõi autor välja
parendamist vajavad valdkonnad. Töötaja rahulolu-uuring aitab ettevõttel saada töötajatelt infot
vajaduste ja muutuste kohta ning vähendab värbamiskulusid ja tööjõuvoolavust. Ettevõtte tööd
aitab korraldada toimiv dokumentatsioon, mis fikseerib tegevused ja otsused. Sellest tulenevalt
toob autor välja ettevõtte dokumentide ülevaatuse, nende uuendamise ja parendamise.In the world, products and service providers are becoming more and more competitive. Quality
is a key factor in both selling the service and shaping the company's reputation. It is necessary
to create a well-functioning quality management system, find competent employees and
suitable partners to work with. The research object is a small company named Amello
Raamatupidamisteenused OÜ, which considers this topic to be important, as the company has
previously not studied or consciously implemented the quality management system. The aim
of the Master's thesis is to analyze the implementation of the quality management system in
Amello Raamatupidamisteenused OÜ and to highlight the areas needed to improve on the basis
of analysis. The author held semi-structured interviews with the chief executive officer and
the software leading specialist of the company as a research method and conducted document
analysis. The analysis showed that the quality management system is not systematically
documented in the company, but the activities are structured and in place. A set of rules,
principles and a description of processes have been developed. ISO compliance occurred, but
not as detailed as ISO requires. Major deficiencies occurred in the documentation, which
included outdated information. As corrective measures, the review of the documentation, their
supplementation and the addition of the missing documentation were introduced. In addition,
it is recommended to carry out regular customer and staff satisfaction surveys in order to take
into account the changing needs of time
The Iambic Muse: Gerty’s Metaformations in Ulysses 13
No full textThis article on Ulysses 13 argues that Gerty’s fetishized feet and lame leg function as
verbal, visual, and aural symbols that guide the readers through an intertextextual
labyrinth. It shows that the Nausicaa episode does not just re-enact the mythic
Homeric encounter between a foreign man and an unguarded girl on the beach of
Phaeacia, but alludes simultaneously and repeatedly to other versions — classical
and modern of the original erotic-elegiac encounter. The author contends that Gerty
MacDowell, like the scriptae puellae of Latin elegy and Ovid in particular, is a textual-
object fabricated by the artist-lover. She is Bloom’s flawed erotic masterpiece
