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Effect of the probe frequency on sensitivity of color Doppler ultrasound to color blood flow: comment on the article by Torp-Pedersen et al., Reply
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Power and Color Doppler Ultrasound Settings for Inflammatory Flow: Impact on Scoring of Disease Activity in Patients With Rheumatoid Arthritis
Get PDFObjective: To determine how settings for power and color Doppler ultrasound sensitivity vary on different high- and intermediate-range ultrasound machines and to evaluate the impact of these changes on Doppler scoring of inflamed joints. Methods: Six different types of ultrasound machines were used. On each machine, the factory setting for superficial musculoskeletal scanning was used unchanged for both color and power Doppler modalities. The settings were then adjusted for increased Doppler sensitivity, and these settings were designated study settings. Eleven patients with rheumatoid arthritis (RA) with wrist involvement were scanned on the 6 machines, each with 4 settings, generating 264 Doppler images for scoring and color quantification. Doppler sensitivity was measured with a quantitative assessment of Doppler activity: color fraction. Higher color fraction indicated higher sensitivity. Results: Power Doppler was more sensitive on half of the machines, whereas color Doppler was more sensitive on the other half, using both factory settings and study settings. There was an average increase in Doppler sensitivity, despite modality, of 78% when study settings were applied. Over the 6 machines, 2 Doppler modalities, and 2 settings, the grades for each of 7 of the patients varied between 0 and 3, while the grades for each of the other 4 patients varied between 0 and 2. Conclusion: The effect of using different machines, Doppler modalities, and settings has a considerable influence on the quantification of inflammation by ultrasound in RA patients, and this must be taken into account in multicenter studies
Power and color Doppler settings for inflammatory flow - impact on scoring of disease activity in patients with rheumatoid arthritis
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Effect of chronic kidney diseases on mortality among digoxin users treated for non-valvular atrial fibrillation:a nationwide register-based retrospective cohort study
Get PDFPURPOSE: This study investigated the impact of chronic kidney disease on all-causes and cardiovascular mortality in patients with atrial fibrillation treated with digoxin.METHODS: All patients with non-valvular atrial fibrillation and/or atrial flutter as hospitalization diagnosis from January 1, 1997 to December 31, 2012 were identified in Danish nationwide administrative registries. Cox proportional hazard model was used to compare the adjusted risk of all-causes and cardiovascular mortality among patients with and without chronic kidney disease and among patients with different chronic kidney disease stages within 180 days and 2 years from the first digoxin prescription.RESULTS: We identified 37,981 patients receiving digoxin; 1884 patients had the diagnosis of chronic kidney disease. Cox regression analysis showed no statistically significant differences in all-causes (Hazard Ratio, HR 0.89; 95% confident interval, CI 0.78-1.03) and cardiovascular mortality (HR 0.88; 95%CI 0.74-1.05) among patients with and without chronic kidney disease within 180 days of follow-up period. No statistically significant differences was found using a 2 years follow-up period neither for all causes mortality (HR 0.90; 95%CI 0.79-1.03), nor for cardiovascular mortality (HR 0.87; 95%CI 0.74-1.02). No statistically significant differences was found comparing patients with and without estimated Glomerular Filtration Rate <30ml/min/1.73m2 and patients with different stages of chronic kidney disease, for all-causes and cardiovascular mortality within 180 days and 2 years from the first digoxin prescription.CONCLUSIONS: This study suggest no direct effect of chronic kidney disease and chronic kidney disease stages on all-causes and cardiovascular mortality within both 180 days and 2 years from the first digoxin prescription in patients treatment-naïve with digoxin for non-valvular atrial fibrillation.</p
Intra-articular distribution pattern after ultrasound-guided injections in wrist joints of patients with rheumatoid arthritis.
No full textComparison of the effects of metoprolol and carvedilol on symptoms, well.-being, and quality-adjusted life-years: A description of the patient-journey in COMET
No full textQuantifying disease activity and damage by imaging in rheumatoid arthritis and osteoarthritis.
No full textComparison of the effects of metoprolol and carvedilol on symptoms, well.-being, and quality-adjusted life-years: A description of the patient-journey in COMET.
No full textSJP964974_Supplemental_Figures – Supplemental material for Work exposure and associated risk of hospitalisation with pneumonia and influenza: A nationwide study
No full textSupplemental material, SJP964974_Supplemental_Figures for Work exposure and associated risk of hospitalisation with pneumonia and influenza: A nationwide study by Lauge Østergaard, Rikke Nørmark Mortensen, Kristian Kragholm, Michael Dalager-Pedersen, Kristoffer Koch, Lars Køber, Christian Torp-Pedersen and Emil Fosbøl in Scandinavian Journal of Public Healt
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