250 research outputs found
The effects of Wnt5a and Wnt3a and PCP signaling on Schwann cell biology and myelination
No full textPlanar cell polarity (PCP) is known as the polarization of cells within the plane of the tissue layer. This form of polarization controls several epithelial and non-epithelial morphological processes, such as the orientation of primary cilia in the inner ear, convergent extension (CE) and directed migration. A three tiered model of PCP regulation has been proposed which consists of the global, core, and effector modules. However there is one addition level of modulation through non-canonical Wnt signaling pathway. Of the many Wnt proteins a few have been identified to signal primarily through this pathway. One such protein is Wnt5a, which has been shown to modulate PCP during directed cell migration. In this study we gather preliminary data for the presence of PCP signaling components in Schwann cells and investigate the effect of Wnt5a and its antagonist Wnt3a on Schwann cell proliferation, migration and myelination.M.S.Includes bibliographical referencesby Neha Jan
The effects of immediate versus delayed feedback after multiple-choice questions on subsequent exam performance
No full textThis thesis investigates the effects of immediate versus delayed feedback following multiple-choice questions on subsequent performance on multiple-choice and recall questions. In three experiments, students in a college psychology lecture course received immediate or delayed feedback following multiple-choice questions on an initial unit exam which was followed up with exam(s) including both multiple-choice and short-answer questions. In the first experiment, the kind of feedback did not affect performance on the same multiple-choice questions when they were repeated on the final. In the second experiment, two subsequent follow-up exams included first a short-answer version of the multiple-choice question and then the same multiple-choice question. Performance on the short-answer questions was better following delayed feedback than following immediate feedback. However, the kind of feedback had no effect on the performance of the repeated multiple-choice questions. Also, the interval between the initial exam and the follow-up exam had no effect on performance. The third experiment examined whether delayed feedback increased confidence more than immediate feedback and whether the increase in confidence mediated the improved performance on subsequent short-answer questions. The delayed feedback had no effect on confidence for the subsequent short-answer and multiple-choice responses. Together, these results demonstrate that delayed feedback improves performance on the short-answer questions by increasing the subsequent generation of the correct response but does not influence recognition of it.M.S.Includes bibliographical referencesIncludes vitaby Neha Sinh
Moral Panic, Social Exclusion and The Human Rights of Same-Sex Partners in Ghana-RETRACTED
No full textThis article is retracted :
The retraction is based on the request of the author, Dr. Neha Jain, as it contains some exclusive and private data of a community out of India, that should not be released online. https://doi.org/10.55938/ijgasr.v1i3.20
Sincerely,Editorial Team, IJGASR
Announcement: https://journals.icapsr.com/index.php/ijgasr/announcement/view/17
Correction to: A cell-cycle signature classifier for pan-cancer analysis
No full textIn the original published version, the list of authors was incomplete. Theodora A. Constantin was missing, and Neha Tabassum and Theodora A. Constantin share first authorship. The correct author list is given above. The original article has been corrected. DOI to original article: https://doi.org/10.1038/s41388-020-01426-
Less-institutionalized social structures: a theoretical, methodological, and empirical analysis of how networks and culture matter for emergence
No full textUsing a networks and culture lens, I investigate the micro-level processes underlying the production of order in social contexts or locations that are relationally-defined and meaningful, but lack cultural cues to action and interpretation or are in the early stages of acquiring such meaning. Drawing on neoinstitutionalist theory, I refer to such social structures as less-institutionalized. To explain order in the absence of situational cultural cues literature in social network analysis has traditionally attributed regularities to situational structural tendencies that preclude shared understandings and/or subjective engagement. Recent literature in the sociology of culture that revives overarching moral intuitions as a basis for action similarly rejects the explanatory value of situational cultural cues. Arguing that culture is neither irrelevant nor implicated in an overarching way in culturally less-institutionalized situations, I posit that order can be linked to individuals’ tacit and discursive use of cultural repertoires acquired over the life-course through involvements in multiple networks of interaction and domains of shared meanings or ‘netdoms.’ I analytically distinguish between three categories of less-institutionalized situations of the basis of the degree of uncertainty in interpretation and action they impose upon their occupants: high, intermediate, and absence/low. I demonstrate my argument using three examples of less-institutionalized situations/positions from distinct sociological fields: (1) rapid labor-force feminization in South Asia (high-uncertainty); (2) an emergent area of knowledge production (intermediate-uncertainty); and (3) falling average sibship-size implicated in worldwide fertility decline (low/absent uncertainty). Elaborating upon three cross-netdom mechanisms - analogizing, contrasting, and spillovers – and using a mixture of interpretive techniques, multilevel statistical models, and exponential random graph models, I show that occupants use cultural repertoires discursively in high-uncertainty less-institutionalized positions, tacitly in low-uncertainty situations, and in a combination of tacit and deliberative ways under conditions of intermediate uncertainty. I also develop a mathematical model to show how less-institutionalized practices/interpretations can come to be institutionalized over time through management of uncertainty within homophilous networks. Lastly, positing a duality between the cultural repertoires of individuals and those of social locations, I conclude with a discussion on how less-institutionalized positions offer a unique window into investigating processes of emergence and social change.Ph. D.Includes bibliographical referencesIncludes vitaby Neha Gonda
Socio-cultural Sustainability through Study Material: English Language Teaching in India
No full textControl of Three Phase Grid Connected Photovoltaic System
No full textTo counter environmental pollution arising out of fossil fuel power generation,the world is gradually shifting towards renewable sources of energy, with solar energy leading at the front. In a grid-connected solar PV system, the energy generation system and utility grid are interfaced by using power electronics converters which are commonly based on a VSI (voltage source inverter) connected to the mains supply network, which is used to regulate power flow and ensuring operation with unity power factor. The grid requirements are improved power quality, Good transient response during fault conditions, grid synchronization and independent control of active & reactive power and etc.
To achieve this requirement of the grid, here we designed a 10kW PV system which is to be interfaced to a utility grid to be performed. This project represents athree-phase, single-stage grid integrated solar PV system. The proposed system serves for power factor correction,the maximum power point tracking (MPPT), the grid 5 currents balancing and harmonics mitigation of loads connected at the PCC (point5 of common coupling). The solar photovoltaic system uses a three- phase VSC (voltage source converter) to perform these functions. This system extracts the solar energy from the photovoltaic system and feeds to the grid.MPPT algorithm is put to use for extracting maximum power from Photovoltaic system. There are many types of MPPT algorithms are there, but especially which are widely used is perturb and observer and incremental conductance algorithm. Here, the proposed system used the incremental conductance which is more accurate and more efficient. The reference DC link voltage of voltage source converter is also decided by the MPPT algorithm.
In a simplified way, the control algorithm of a solar photovoltaic system consists of two parts, in the first part the MPPT decides the reference D.C. link voltage and secondly the VSC is controlled by the use of control functions. The PV system voltage is maintained at the reference which is controlled by a PI(proportional integral)controller using an MPPT algorithm. For controlling the VSC, an Improved linear sinusoidal tracer (ILST) and Damped-second order generalized integrator (Damped-SOGI) is proposed. The main characters of the Improved linear sinusoidal tracer control algorithm are fast convergence, control simplicity while the Damped-SOGI is having the higher converging state, good noise immunity response and improved steady-state performance. The fundamental component of the load current is extracted by using an ILST and a Damped-SOGI based control algorithm, zero crossing detectors and sample and hold log are used to extract the active power component of load currents. PI controller is used to estimate the loss component of VSC and reference grid currents are estimated by combining all these components. The sensed grid currents and the reference grid currents are compared and a current controller is used for producing the switching pulses for the grid VSC interfaced. The unity power factor (UPF),as well as the sinusoidal balancing of grid currents, are controlled by the VSC. The currents injected into the grid are synchronized using unit templates derived from PCC voltages. Only active power is exchanged through the grid because the grid currents are at UPF. The total active power in the system must be balanced among the grid, the loads and the SPV. There is a comparison between the Damped SOGI and ILST algorithm on the basis of THD and other waveforms. The simulation results are obtained by using MATLAB/Simulink for controlling the active current between the PV-grid systems
Problematyka zrównoważonego rozwoju społeczno-kulturowego w materiałach dydaktycznych: Nauczanie języka angielskiego w Indiach
No full textTeaching materials are the primary source of input in the language classroom. The potential of English language teaching (ELT) materials to preserves and transmit our culture, value, identity, and language make it significant for socio-cultural sustainability. The materials developed by the National Council of Education and Research Training (NCERT) are far and wide running study materials in primary and secondary schools in India. India exhibits a massive variety of cultures, customs, languages, and religious beliefs. The selection and development of apt materials is, therefore, a matter of serious deliberation. The centrally developed material, despite numerous benefits, often lacks in representing different groups of students, especially the backward and marginalized ones. The contents, in most cases, are representative of the mainstream. Therefore, the study suggests teachers developed supplementary materials to which learners from all the groups can relate. The researcher has taken the context of Jharkhand and illustrates self-developed supplementary materials prepared using contents from learners’ social and cultural backgrounds. The article offers various suggestions on how to develop such materials that could bring socio-cultural equity in the classroom, making a significant contribution to social sustainability.Materiały dydaktyczne są głównym źródłem informacji w klasie językowej. Potencjał materiałów do nauczania języka angielskiego (ELT) w ochronie i przekazywaniu naszej kultury, wartości, tożsamości i języka sprawia, że są one istotne z perspektywy zrównoważonego rozwoju społeczno-kulturowego. Materiały opracowane przez National Council of Education and Research Training (NCERT) są szeroko stosowanymi materiałami do nauki w szkołach podstawowych i średnich w Indiach. Indie wykazują ogromną różnorodność kultur, zwyczajów, języków i przekonań religijnych. Wybór i opracowanie odpowiednich materiałów jest zatem kwestią poważnej refleksji. W materiale opracowanym centralnie, mimo licznych korzyści, często brakuje reprezentacji różnych grup uczniów, zwłaszcza tych zacofanych i marginalizowanych. Treści w większości przypadków są reprezentatywne dla głównego nurtu. W związku warto zasugerować nauczycielom opracowanie materiałów uzupełniających, do których mogą odnieść się uczniowie ze wszystkich grup. W artykle przyjęto perspektywę Jharkhanda i przedstawiono własne materiały uzupełniające wykorzystujące treści pochodzące ze środowisk społecznych i kulturowych uczniów. Artykuł zawiera konretne sugestie dotyczące opracowywania takich materiałów, które mogłyby zapewnić równość społeczno-kulturową w klasie, wnosząc znaczący wkład w zrównoważony rozwój społeczny
Rola języka w zrównoważonym rozwoju: wielojęzyczność i umiejętność czytania i pisania w Indiach
No full textThe paper, out of the three major domains of sustainable development, brings its focus on socio-cultural sustainability. As human contacts and negotiation are essential to serve the purposes of sustainable development worldwide, language as a shared means of communication is worth paying attention to. The central objective of the paper is to deliberate on the significance of language and literacy in sustainable development. Firstly, it introduces the notion of sustainable development and conceptualizes language within its frame. Then, it explores the link between language, literacy and development; and elucidates the role this plays in attaining sustainable development goals. The paper further highlights the debate between English and mother tongue/local languages specific to the literacy programmes in India. Conflicts in language selection for the medium of instruction, deciding on the place of mother tongue and global language, etc are some obvious issues in the multilingual and multicultural education scenario. Therefore, the paper calls for the need of adopting a multilingual approach in order to address the linguistic diversity in the multilingual educational contexts. Both English and local languages have been equally emphasized for attaining social sustainability at the local and global plane. Some implications are also suggested to be utilized in language/educational programmes.Niniejszy artykuł, spośród trzech głównych filarów zrównoważonego rozwoju, koncentruje się na zrównoważeniu społeczno-kulturowym. Ponieważ kontakty międzyludzkie i negocjacje są niezbędne, by służyć zrównoważonemu rozwojowi na całym świecie, warto zwrócić uwagę na język jako wspólny środek komunikacji. Głównym celem artykułu jest rozważenie znaczenia języka i umiejętności czytania i pisania o zrównoważonym rozwoju. Po pierwsze, wprowadza pojęcie zrównoważonego rozwoju i konceptualizuje język w jego ramach. Następnie bada związek między językiem, umiejętnością czytania i rozwoju oraz wyjaśnia rolę, jaką odgrywa w osiąganiu celów zrównoważonego rozwoju. Artykuł dodatkowo omawia relację między językiem angielskim a językiem ojczystym / językami lokalnymi w kontekście programów alfabetyzacji w Indiach. Konflikty w wyborze języka jako środka nauczania, decydowania o miejscu języka ojczystego i języka globalnego itp. to pewne oczywiste problemy w scenariuszu edukacji wielojęzycznej i wielokulturowej. W związku z tym w artykule postuluje się przyjęcie podejścia wielojęzycznego w celu uwzględnienia różnorodności językowej wielojęzycznych klas. Podkreślono rolę zarówno języka angielskiego, jak i lokalnego, jako drogi do osiągnięcia równowagi społecznej na płaszczyźnie lokalnej i globalnej. Autorzy wskazują również, na niektóre rozwiązania, które można wykorzystać w programach językowych / edukacyjnych
Competing bimetallic ratios: Amsterdam, London and bullion arbitrage in the 18th century
No full textThis article analyses the stability of bimetallism in the mid-18th century for the case of two large centres that had different legal ratios and only one international market ratio. A new theoretical framework is articulated for the situation of international independence to set legal bimetallic ratios by monetary authorities in different countries. Then, using new data handcollected from archival sources and relevant to the two main bullion markets in the 18th century, Amsterdam and London, this theoretical framework is utilised to identify the regimes that actually prevailed during that period, in which Amsterdam was effectively on the bimetallic standard while London was on the gold standard de facto.Bimetallism, Bimetallic stability, Bullion markets, Arbitrage, Specie-point mechanism, Melting-minting points
- …
