296 research outputs found
Correction to: Associations of whole blood polyunsaturated fatty acids and insulin resistance among European children and adolescents (179: 1647-1651, 2020)
No full textThe article “Associations of whole blood polyunsaturated fatty acids and insulin resistance among European children and adolescents”, written by Sarah Marth, Claudia Börnhorst, Kirsten Mehlig, Paola Russo, Luis A. Moreno, Stefaan De Henauw, Toomas Veidebaum, Dénes Molnár, Michael Tornaritis, Patrizia Risé, Maike Wolters, on behalf of the IDEFICS and I.Family consortia, was originally published Online First without Open Access..
EESTI TERVISEUURING 2006. Eessõna
No full textEesti Arsti erinumber sisaldab lühiülevaadet Eesti terviseuuringu 2006 (ETeU 2006) tulemustest erinevate tervisevaldkondade kaupa. ETeU 2006 on teine suuremahuline Eesti täiskasvanud elanikkonda hõlmav küsitlusuuring, mille põhieesmärkideks on saada ülevaade rahvastikustruktuurile vastavast terviseseisundist ning selle seostest sotsiaalsete ja käitumuslike näitajatega, samuti tervist kahjustavate riskitegurite levimusest.
Eesti Arst 2008; 88(Lisa2):
Kolhitsiini mõjust kana embrüode esmaskultuuri rakkudele
No full texthttps://www.ester.ee/record=b5456229*es
Digital media exposure and cognitive functioning in European children and adolescents of the I.Family study
No full textThe digital environment can pose health risks through exposure to unhealthy content. Yet, little is known about its relation to children’s cognitive functioning. This study investigates the association between digital media (DM) exposure and children’s cognitive functioning. This cross-sectional study is based on examinations of children aged 8–18 years (N = 8673) of the I.Family cohort (2013–2014). Exposure to television, computer, smartphone and internet was self-reported (hours/day). Media multitasking (MMT) was defined as simultaneous use of computers with other digital or non-screen-based activities. Standard instruments were used to assess cognitive inflexibility (score: 0–39), decision-making ability (− 100 to + 100) and impulsivity (12–48). Adjusted regression coefficients and 99.9%CIs were calculated by generalized linear mixed-effects models. In total, 3261 participants provided data for impulsivity, 3441 for cognitive inflexibility and 4046 for decision-making. Exposure to smartphones and media multitasking were positively associated with impulsivity (βsmartphone = 0.74; 99.9%CI = 0.42–1.07; βMMT = 0.73; 99.9%CI = 0.35–1.12) and cognitive inflexibility (βsmartphone = 0.32; 99.9%CI = -0.02–0.66; βMMT = 0.39; 99.9%CI = 0.01–0.77) while being inversely associated with decision-making ability. Extensive smartphone/internet exposure combined with low computer/medium TV exposure was associated with higher impulsivity and cognitive inflexibility scores, especially in girls. DM exposure is adversely associated with cognitive functioning in children and adolescents. Children require protection against the likely adverse impact of digital environment. CC BY 4.0 DEED© 2023, The Author(s)Correspondence Address: A. Hebestreit; Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany; email: [email protected]. Family consortium: Elida Sina, Christoph Buck, Wolfgang Ahrens, Juul M. J. Coumans, Gabriele Eiben, Annarita Formisano, Lauren Lissner, Artur Mazur, Nathalie Michels, Dénes Molnar, Luis A. Moreno, Valeria Pala, Hermann Pohlabeln, Lucia Reisch, Michael Tornaritis, Toomas Veidebaum & Antje HebestreitAuthor correction in: Scientific Reports, Volume 13, December 2023, Article number: 22595. doi:s41598-023-49411-8The original version of this Article contained an error in the I. Family consortium, where authors Christoph Buck, Wolfgang Ahrens, Juul M. J. Coumans, Luis A. Moreno, Hermann Pohlabeln, Michael Tornaritis, Toomas Veidebaum and Antje Hebestreit were omitted as Consortium Members.The research was done in the framework of the I.Family study (http://www.ifamilystudy.eu). We are thankful for the participation of European children and adolescents and their parents in our study as well as the support received from school boards, headmasters, and communities.Open Access funding enabled and organized by Projekt DEAL. This research was funded by the European Community within the Seventh RTD Framework Programme Contract No. 266044. The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.</p
The Potential of Integrative Cancer Treatment Using Melatonin and the Challenge of Heterogeneity in Population-Based Studies: A Case Report of Colon Cancer and a Literature Review
No full textMelatonin is a multifunctional hormone regulator that maintains homeostasis through circadian rhythms, and desynchronization of these rhythms can lead to gastrointestinal disorders and increase the risk of cancer. Preliminary clinical studies have shown that exogenous melatonin alleviates the harmful effects of anticancer therapy and improves quality of life, but the results are still inconclusive due to the heterogeneity of the studies. A personalized approach to testing clinical parameters and response to integrative treatment with nontoxic and bioavailable melatonin in patient-centered N-of-1 studies deserves greater attention. This clinical case of colon cancer analyzes and discusses the tumor pathology, the adverse effects of chemotherapy, and the dynamics of markers of inflammation (NLR, LMR, and PLR ratios), tumors (CEA, CA 19-9, and PSA), and hemostasis (D-dimer and activated partial thromboplastin time). The patient took melatonin during and after chemotherapy, nutrients (zinc, selenium, vitamin D, green tea, and taxifolin), and aspirin after chemotherapy. The patient’s PSA levels decreased during CT combined with melatonin (19 mg/day), and melatonin normalized inflammatory markers and alleviated symptoms of polyneuropathy but did not help with thrombocytopenia. The results are analyzed and discussed in the context of the literature on oncostatic and systemic effects, alleviating therapy-mediated adverse effects, association with survival, and N-of-1 studies
Sleep duration and blood pressure in children: Analysis of the pan-European IDEFICS cohort
No full textThe present study aims to examine the cross-sectional and longitudinal association between self-reported nocturnal sleep duration, blood pressure, and hypertension in European children, aged 2-9.9 years, participating in the IDEFICS project. Blood pressure (BP) and the main anthropometric indices were measured according to standardized procedures. Childhood elevated BP and hypertension were defined according to the European Society of Hypertension Guidelines for children and adolescents. Parents reported lifestyle and socio-demographic data. Nocturnal sleep duration was assessed as part of a parental 24-h recall and categorized as follows: (a) <= 9 hours/night; (b) >9 hours to <= 10 hours/night; (c) >10 hours to <= 11 hours/night; and (d) >11 hours/night. A complete set of variables included in the present analysis was provided by 7974 participants (boys/girls = 4049/3925) at the baseline survey (T0). Of them, 5656 were re-examined 2 years later at follow-up (T1). Children reporting shorter sleep duration at T0 had significantly higher BP values (P for trend < 0.001) compared to those who slept more. Prospective analyses showed that shorter sleep duration at baseline predicted, over the 2-year follow-up, higher increases in systolic blood pressure and diastolic blood pressure, after adjustment for age, sex, country of origin, BMI z-score, parental education, physical activity, screen time, and T0 value of the examined outcome variables (P for trend < 0.001). Our findings reveal that shorter sleep duration is associated with higher BP in childhood, suggesting that sleep may be a potential risk factor for hypertension later in life
Täiendavad võimalused pikaajaliste kutseekspositsioonide toksilise toime hindamiseks
No full textPikaajaline ekspositsioon töökeskkonnas sisalduvatele orgaaniliste lahustite, diiselheitgaaside ning keevitusaurudele põhjustab mitmesuguseid tervisehäireid. Loetletud õhusaastekomponendid mõjutavad oluliselt porfüriini ja heemi ainevahetust, vallandades ainevahetushäirete ahela. Raskemetallide, porfüriini ja heemi ainevahetuse näitajate uurimine veres annab lisainfot mitmesuguste kutsekahjustuste hindamiseks.
Eesti Arst 2004; 83 (12): 806–81
- …
