1,720,959 research outputs found
Un paradosso solo apparente: metopismo associato a craniostenosi. Trattamento chirurgico originale
No full textAN ONLY APPARENT PARADOX: METOPISM AND CRANIOSYSNOSTOSIS. AN ORIGINAL SURGICAL TREATMENT. Since tha dawn of civilty skull deformities have been considered as a sign fo Divinity, as they were a privilege, so that they have been also induced by sophysticated technique of asymmetrical skull compression. Gerolamo Cardano (1501-1576) descibed the art of divining the future by the study of the forehead and defined metopism the middle skull bones discontinuity due to diastais of the metopic and sagittal sutures. Craniosysnostosis is a premature fusion of one or more craniofacial sutures' systems, leading to craniofacial deformities. These malformation can be treated through a surgical technique that is undergoing continuous evolution. In the two cases reported, an Apert syndrome and brachycefaly both associated with metopism, we thought that decompression and remodelling wouldn't be adequate enough. The two little girls have been operated early (two months old) using an original technique which allowed decompression and remodelling of the volt, bases and orbits, in order to leave them room to develop. We also performed a sort of "bone synthesis" of the metopic suture using autologous bone fragments (acquired from the decompressive craniectomy) and human dura mater sterilized with gamma-rays for this purpose. Careful neuroradiologic study, especially 3D Computed Axial Tomography, enabled us to demonstrate the aesthetic and functional excellence of our results, since the very postoperatory time until more than five years of follow-up. We demonstrated re-expansion, the total remodelling and the correction of metopism with a good calcification of th metopic suture
Contributo critico alla diagnosi ed al trattamento della malformazioni vascolari cerebrali criptiche e venose, in particolare nell'infanzia
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Lafora's disease. Clinical, histological ultrastructural and biochemical study
No full textClinical, electroencephalographic, neuropathological and biochemical data from a 16 yr old patient with progressive myoclonus epilepsy (PME) of the Lafora type are reported. Histological data show the presence of neuronal loss and gliosis. Electron microscopic observations show the presence of Lafora bodies in neurons with a dense central core and a more lightly staining rim. They are composed of fibrils and granules. The biochemical studies show a decrease of cholesterol (30.8% of control values), glycolipids (29.8%), and phospholipids (50%). Insoluble glycoprotein NaNa and hexosamines were decreased to 13.28% and 17.39%, respectively; soluble glycoprotein NaNa was unchanged, while hexosamines were increased 155.68%. A marked increase was found for insoluble mucopolysaccharides (348.82%). These changes led to speculations concerning the biochemical basis of this syndrome
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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