1,720,992 research outputs found
Management of Patients Taking Oral Anticoagulants Who Need Urgent Surgery for Hip Fracture. . doi: 10.1055/s-0039-1678718. Epub 2019 Feb 11. PubMed PMID: 30743280.
No full textLiquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant
No full textPostpartum haemorrhage in a woman with essential thrombocythemia carrying calreticulin mutation: a case report.
No full textAnnexin V expression in human placenta is influenced by the carriership of the common haplotype M2
No full text
A new JAK2 gene mutation in patients with polycythemia vera and splanchnic vein thrombosis.
No full text
Annexin V expression in human placenta is influenced by the carriership of the common haplotype M2.
No full textMaternal thrombophilia and the risk of recurrence of preeclampsia
No full textOBJECTIVE: The aim of this prospective study was to determine the impact of thrombophilia on the recurrence of preeclampsia.
STUDY DESIGN: In a multicenter, observational, cohort design, 172 white patients with a previous pregnancy complicated by preeclampsia were observed in the next pregnancy. They were evaluated for heritable thrombophilia (factor V Leiden and factor II G20210A mutations, protein S, protein C, and antithrombin deficiency), hyperhomocystinemia, lupus anticoagulant, and anticardiolipin antibodies. Development of preeclampsia and maternal complications and both gestational age at delivery and birthweight were recorded.
RESULTS: Sixty women (34.9%) showed the presence of a thrombophilic defect. They had a higher risk for the recurrence of preeclampsia (odds ratio [OR], 2.5; 95% confidence interval [CI], 1.2-5.1), compared to patients without thrombophilia. Similar findings were observed considering only heritable thrombophilia. Thrombophilic patients were at increased risk for the occurrence of very early preterm delivery (< 32 weeks; OR, 11.6; 95% CI, 3.4-43.2).
CONCLUSION: When counseling white women with a history of preeclampsia, screening for thrombophilia can be useful for preconceptional counseling and pregnancy management
- …
