262 research outputs found

    The Global Art Gallery Report with Richard Taittinger, Magnus Resch, Stefania Bortolami, and James Fuentes

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    Moderator: Magnus Resch Book Author and Art Entrepreneur Panelists: Stefania Bortolami, Gallery Owner James Fuentes, Gallery Owner Richard Taittinger, Gallery Owner The Global Art Gallery Report is the first and the most wide-ranging report on today\u27s commercial art galleries. Published by Phaidon, it is the first insight of its kind, presenting a detailed and comprehensive portrait of today\u27s gallery scene. In a panel discussion, Magnus Resch will discuss his findings with gallerists Jeffrey Deitch, Stefania Bortolami and James Fuentes. Panelists will shine a light on the future of the art gallery. Founded in 1969, the Sotheby’s Institute of Art is the first and foremost graduate school for the study of art and its markets. With more than 6,000 alumni working internationally in art fairs, galleries, museums, auction houses, and nonprofits, the Institute’s alumni are shaping the future of the art industry. Past guest speakers at the Institute have included artists, such as: Ulay and Jaša, Dan Graham, Alexandre Singh, Glenn Ligon, Sanford Biggers, Carolee Schneemann, Dara Birnbaum, Alfredo Jaar, Ahmed Alsoudani; and art industry experts from Sotheby’s, Art Basel, Paddle8, Auctionata, Armory Show, Artsy, Whitney Museum, Swiss Institute, MoMA, and others.https://digitalcommons.sia.edu/speaker/1007/thumbnail.jp

    Early experience with a modified preloaded system for fenestrated endovascular aortic repair

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    Objective Preloaded endovascular delivery systems expand the anatomic eligibility for complex aortic repair by requiring only one iliac access vessel and providing a stable platform for guiding sheaths into challenging target vessels. This article reports the lessons learned and early clinical outcomes using a modified preloaded delivery system for fenestrated endovascular aneurysm repair (FEVAR) in three aortic centers in Europe. Methods From October 2015 to March 2016, consecutive patients presenting with extensive aortic aneurysm treated with a modified preloaded FEVAR were prospectively enrolled from three high volume European aortic centers. The new design is a modification of previous designs of preloaded fenestrated stent grafts and of the p-branch device platform. The technical details of implantation are described and perioperative outcomes, including the learning curve, are collected and reported. Results All patients (30 patients; 80% men; 70.2 years old) presented for nonurgent repair of either a type Ia endoleak (3/30; 10%), a type I-II-III thoracoabdominal (8/30; 27%), or a type IV thoracoabdominal or pararenal (19/30; 63.%) aneurysm repair of a mean size of 64 ± 13 mm using a custom made device. Primary technical success was achieved in 28 of 30 patients (93%) and assisted primary technical success in 29 of 30 patients (97%). The two technical failures included open conversion to repair a ruptured iliac artery and restenting of a dissected superior mesenteric artery which was recognized hours after the index procedure had finished. The mean procedure time was 277 ± 153 minutes, fluoroscopy time 79 ± 36 minutes, dose area product 112 ± 90 Gy cm2, and contrast volume 87 ± 46 mL. All renal fenestrations were successfully stented without type III endoleak on completion angiogram; the preloaded guiding sheaths were used for 53 of 58 renal arteries (91%). Challenges related to learning to the use of the modified preloaded system were experienced early and had no clinical consequences. Major complications occurred in seven cases (23%), including two perioperative deaths because of stroke and sepsis following primary conversion attributable to iliac rupture. There were no target vessel occlusions or type I/III endoleaks found on postoperative imaging. Conclusions Based on early experience, the modified preloaded system can be safely and effectively used during FEVAR, with good technical result and a short period of learning. This device expands treatment to patients with compromised iliac access, thus, additional patients and more follow-up will be required to determine unique risks of operating in this patient population

    A Sigh of Mystery: Karl Barth's Theology of the Virgin Birth

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    title: A Sign of Mystery: Karl Barth's Theology of the Virgin Birth, author: Dustin Resch, location: MillsIn this study, I examine Karl Barth's doctrine of the virgin birth of Christ in relation to his discussions in the Church Dogmatics of Christology, pneumatology and interpretation of Scripture. I argue that the virgin birth of Jesus Christ is understood by Barth as a fitting sign to expresses the form of the dialectic of God's "No" to sin and "Yes" to humanity in his free act of revelation and reconciliation. As such, the doctrine of the virgin birth functions for Barth as a paradigm through which to understand the fashion of God's work upon human beings and the suitable posture of a human being before God. I demonstrate this conviction by providing an overview of select interpreters of the doctrine of the virgin birth in the western Christian tradition in order to set Barth's contribution in its theological context. I then provide an exposition of the methodological and exegetical features of Barth's development of the doctrine of the virgin birth from his first professorship up to the introductory volume of the CD. Next, I examine how Barth's doctrine of the virgin birth fit with his broader Christology and pneumatology as represented in the CD. Finally, I provide an exposition of Barth's treatment of the figure of Mary as a capstone to the themes previously outlined. The thesis concludes with a series of probing questions about the implications of Barth's doctrine of the virgin birth for his broader theology.ThesisDoctor of Philosophy (PhD

    Origami based Mechanical Metamaterials

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    We describe mechanical metamaterials created by folding flat sheets in the tradition of origami, the art of paper folding, and study them in terms of their basic geometric and stiffness properties, as well as load bearing capability. A periodic Miura-ori pattern and a non-periodic Ron Resch pattern were studied. Unexceptional coexistence of positive and negative Poisson's ratio was reported for Miura-ori pattern, which are consistent with the interesting shear behavior and infinity bulk modulus of the same pattern. Unusually strong load bearing capability of the Ron Resch pattern was found and attributed to the unique way of folding. This work paves the way to the study of intriguing properties of origami structures as mechanical metamaterials.Includes Supplementary Informatio

    Pararenal aneurysms: currently available fenestrated endografts.

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    Endovascular aneurysm repair (EVAR) is a valid treatment option for abdominal aortic aneurysm (AAA). The outcome of infrarenal EVAR is dependent on choosing patients with appropriate anatomy to allow for good proximal and distal seal. In the absence of an infrarenal neck of adequate length and quality, fenestrated stent-graft repair has emerged as an alternative treatment option. For the past decade there has only been one type of fenestrated endograft on the market. This has shown good short- and midterm outcome in many centers. This graft is custom designed for each individual patient. Over the past few years further development has led to the introduction of new, off-the-shelf stent-graft for fenestrated repair and some new companies have entered the marketplace. Most of these new devices are still in their infancy and currently undergoing clinical trials but add promise to the development of pararenal aortic repair

    Latest developments in TEVAR.

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    Acute type B dissection: endovascular repair or open surgery?

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    Acute dissection of the descending thoracic aorta is often a life threatening disease. If complicated by rupture or organ malperfusion, immediate invasive treatment is mandatory to prevent death. Open surgery by interposition grafting or visceral fenestration is complex and associated with high morbidity and mortality. The introduction of endovascular stentgraft repair has offered a minimally invasive option to this patient group. This review aims to highlight the underlying pathophysiology and epidemiology of complex aortic dissection as well as its treatment

    Systematic Review and Meta-Analysis of the Incidence of Rupture, Repair, and Death of Small and Large Abdominal Aortic Aneurysms under Surveillance

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    Background: The ultimate goal of treating patients with abdominal aortic aneurysms (AAAs) is to repair them when the risk of rupture exceeds the risk of repair. Small AAAs demonstrate a low rupture risk, and recently, large AAAs just above the threshold (5.5–6.0 cm) seem to be at low risk of rupture as well. The present review aims to investigate the outcomes of AAAs under surveillance through a comprehensive systematic review and meta-analysis. Methods: PubMed, Embase, and the Cochrane Central Register were searched (22 March 2022; PROSPERO; #CRD42022316094). The Cochrane and PRISMA statements were respected. Blinded systematic screening of the literature, data extraction, and quality assessment were performed by two authors. Conflicts were resolved by a third author. The meta-analysis of prevalence provided estimated proportions, 95% confidence intervals, and measures of heterogeneity (I2). Based on I2, the heterogeneity might be negligible (0–40%), moderate (30–60%), substantial (50–90%), and considerable (75–100%). The primary outcome was the incidence of AAA rupture. Secondary outcomes included the rate of small AAAs reaching the threshold for repair, aortic-related mortality, and all-cause mortality. Results: Fourteen publications (25,040 patients) were included in the analysis. The outcome rates of the small AAA group (<55 mm) were 0.3% (95% CI 0.0–1.0; I2 = 76.4%) of rupture, 0.6% (95% CI 0.0–1.9; I2 = 87.2%) of aortic-related mortality, and 9.6% (95% CI 2.2–21.1; I2 = 99.0%) of all-cause mortality. During surveillance, 21.4% (95% CI 9.0–37.2; I2 = 99.0%) of the initially small AAAs reached the threshold for repair. The outcome rates of the large AAA group (>55 mm) were 25.7% (95% CI 18.0–34.3; I2 = 72.0%) of rupture, 22.1% (95% CI 16.5–28.3; I2 = 25.0%) of aortic-related mortality, and 61.8% (95% CI 47.0–75.6; I2 = 89.1%) of all-cause mortality. The sensitivity analysis demonstrated a higher rupture rate in studies including <662 subjects, patients with a mean age > 72 years, >17% of female patients, and >44% of current smokers. Conclusion: The rarity of rupture and aortic-related mortality in small AAAs supports the current conservative management of small AAAs. Surveillance seems indicated, as one-fifth reached the threshold for repair. Large aneurysms had a high incidence of rupture and aortic-related mortality. However, these data seem biased by the sparse and heterogeneous literature overrepresented by patients unfit for surgery. Specific rupture risk stratified by age, gender, and fit-for-surgery patients with large AAAs needs to be further investigated

    The selective addition of water

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    Water is omnipresent and essential. Yet at the same time it is a rather unreactive molecule. The direct addition of water to C[double bond, length as m-dash]C double bonds is therefore a challenge not answered convincingly. In this perspective we critically evaluate the selectivity and the applicability of the different catalytic approaches for water addition reactions: homogeneous, heterogeneous and bio-catalytic. Here we would like to discuss how to speed up water addition and even make it selective.BiotechnologyApplied Science
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