463 research outputs found

    Incidence and mortality from malignant mesothelioma 1982-2020 and relationship with asbestos exposure: the Australian Mesothelioma Registry

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    Objectives: malignant mesothelioma is an uncommon cancer associated with asbestos exposure, predominantly occupational. Asbestos has been banned in Australia since 2003 but mesothelioma has a long latency and incident cases continue to present. The Australian Mesothelioma Registry was incepted to collect systematic data about incidence and mortality alongside asbestos exposure.Methods: benefiting from the Australian national system of cancer notification, all incident cases of mesothelioma in all states and territories are fast-tracked and notified regularly. Notified patients are contacted asking for consent to collect exposure information, initially by postal questionnaire and subsequently by telephone interview. Age-standardised annual incidence rates and mortality rates were calculated. Asbestos exposure was categorised as occupational, non-occupational, neither or, both; and as low, or high, probability of exposure.Results: mesothelioma incidence appears to have peaked. The age-standardised incidence rates have declined steadily since the early 2000s (peaking in males at 5.9/100 000 and in all-persons at 3.2/100 000), driven by rates in males, who comprise the majority of diagnosed cases. Rates in women have remained fairly stable since that time. Age-standardised mortality rates have followed similar trends. Mesothelioma remains the most common in those aged over 80 years. Nearly all (94%) cases were linked with asbestos exposure (78% occupational in men; 6.8% in women).Conclusions: with effective control of occupational asbestos use, the decline in age-standardised incidence and death rates has occurred. Incidence rates among women, in whom occupational asbestos exposure is rarely detectable, remain unchanged, pointing to the role of household and /or environmental asbestos exposure.</p

    WLJS-FM, 1976-1977 Campus Radio Station 14

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    WLJS was created for entertainment and information to Jacksonville State University and its surrounding community. Shown are students Rex Wilson, Al Rubin, Tim Baird, Dave Driscoll, Rod Steward, Anthony Robertson, second row, John McAfee, Roger O\u27Neal, P.J. Moss, Tim McDow, Leo Davis, Jim Lewis, Joe A. Holland.https://digitalcommons.jsu.edu/lib_ac_histimg_1970/5367/thumbnail.jp

    WLJS-FM, 1976-1977 Campus Radio Station 13

    No full text
    WLJS was created for entertainment and information to Jacksonville State University and its surrounding community. Shown are students Rex Wilson, Al Rubin, Tim Baird, Dave Driscoll, Rod Steward, Anthony Robertson, second row, John McAfee, Roger O\u27Neal, P.J. Moss, Tim McDow, Leo Davis, Jim Lewis, Joe A. Holland.https://digitalcommons.jsu.edu/lib_ac_histimg_1970/5366/thumbnail.jp

    Information Literacy Seven Corners: Improving instruction by reviewing how librarians, faculty culture, professional literature, technology, and today’s college students converge

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    This article reviews library and education literature, as well as the author’s personal observation of undergraduate information literacy (IL) instruction sessions, and provides a range of ideas and suggestions for ways in which librarians can increase the effectiveness of IL instruction sessions. The author asserts that there are five major influences that present challenges and opportunities to librarians who wish to increase authentic collaboration with faculty for course-integrated instruction that more fully addresses the higher-thinking skills true information literacy requires. In today’s world of expanded electronic access to information and the impact ubiquitous Internet searching has had on students entering or returning to post-secondary education, new strategies must be employed to facilitate instruction that goes beyond procedural skills – the conceptual aspects of information literacy and critical thinking must come to the forefront of library and classroom instruction

    Enacting Kaitiakitanga: Challenges and Complexities in the Governance and Ownership of Rongoā Research Information

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    This article explores the tensions one research team has faced in securing appropriate governance or stewardship (which we refer to as kaitiakitanga) of research data. Whilst ethical and regulatory frameworks exist which provide a minimum standard for researchers to meet when working with Māori, what our experience has highlighted is there is currently a “governance” gap in terms of who should hold stewardship of research data collected from Māori individuals or collectives. In the case of a project undertaken in the traditional healing space, the organisation best placed to fulfil this governance role receives no funding or support to take on such a responsibility; consequently by default, this role is being borne by the research team until such time as capacity can be built and adequate resourcing secured. In addition, we have realised that the tensions played out in this research project have implications for the broader issue of how we protect traditional knowledge in a modern intellectual property law context, and once again how we adequately support those, often community-based organisations, who work at the interface between Indigenous knowledge and the Western world

    Insulin-like factor 3 levels in amniotic fluid of human male fetuses

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    © The Author 2008. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: [email protected]: Rodent studies suggest that the peptide hormone insulin-like factor 3 (Insl3) made by the fetal testis is responsible for the first transabdominal phase of testicular descent, and may be affected by xenobiotics to disrupt male reproductive tract development. To date, there is very little information on the production of INSL3 by the human fetus during gestation. The objective of the present study was to determine the concentrations and time course during pregnancy of INSL3 and testosterone production in human fetuses and their associations with maternal characteristics, pregnancy complications and outcome. METHODS: This is a retrospective cohort study in which women who contributed amniotic fluid specimens to a bank from 2003–2006 were followed to determine their pregnancy complications and pregnancy outcome. Amniotic fluid specimens were collected from the Reproductive Genetics Laboratory of the Hospital of the University of Pennsylvania subsequent to routine amniocentesis. INSL3 and total testosterone levels were measured in amniotic fluid (from n = 50 female, n = 237 male fetuses) by validated immunoassays and correlated with maternal characteristics, pregnancy complications and outcomes. RESULTS: INSL3 was only detectable in amniotic fluid from male fetuses, and highest levels occurred from weeks 15–17 of gestation. INSL3 concentration was positively associated with increased birth weight, the occurrence of pre-eclampsia and advanced maternal age, but not with testosterone levels. CONCLUSIONS: INSL3 concentration in human amniotic fluid is potentially predictive of fetal sex and pre-eclampsia, and presumably reflects the functioning of the fetal Leydig cell populationRavinder Anand-Ivell, Richard Ivell, Deborah Driscoll and Jeanne Manso
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