163,256 research outputs found
Identification and Antifungal Susceptibility Pattern of Candida Species Causing Oral Thrush and Vaginal Candidiasis
No full textCandidiasis: A disease, which though common yet often neglected, has caused more havoc than reported and with the increase in antimicrobial resistance, antifungal agents that are more effective are to be used. The aim of this work is to identify Candida species causing oral thrush and vaginal candidiasis in Awka, Nigeria and evaluate the effect of Fluconazole and Nystatin in-vitro against them. Using standard microbiological tests in identification, 80 samples (43.24%) were positive for Candida out of the 185 samples gotten from the study subjects. Candida albicans (55%), C.tropicalis (35%) and C.glabrata (10%) were isolated from the oral cavity while Candida albicans (35%), C.krusei (31.67%), C.tropicalis (15%), C.dublinensis (8.33%), C.glabrata (5.00%), and C.parapsilosis (5.00%) were isolated from the vagina. Fluconazole (50µl) and Nystatin (100 Units) were employed in the anticandidal sensitivity test using agar well diffusion method. More susceptibility to Nystatin than Fluconazole was recorded. From the oral cavity, C.tropicalis was the most susceptible while C.glabrata and C.parapsilosis were the most susceptible species from the HVS samples. This reveals the increase in isolation of non-albicans Candida (NAC) and their growing resistance to Fluconazole which is commonly used hence the need to employ Nystatin as a first line drug for the treatment of oral thrush and vaginal candidiasis
Newfoundland Thrush
No full textNewfoundlandRobin or Newfoundland Thrush Cat: 29:29 _Turdus migratorius nigrideus_ Aldrich & Nutt. pp. 75, 76 above.PRINTED ITEM DNE-citBanks' names see p. 390W. J. KIRWIN MAR 1974 JH MAR 1974Used I and SupUsed IUsed
[Report to Chief J. E. Curry, by an unknown author #1]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
[Report to Chief J. E. Curry, by an unknown author #2]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
The A.N.E.C. IV "Missel Thrush" light airplane
No full textA product of the Air Navigation Engineering Co., the Missel Thrush is a light airplane suitable for private ownership. It is a two seat tractor fuselage biplane with single I interplane struts designed by J. Bewsher
Spatial variation in functional group diversity in a sandflat benthic community: implications for ecosystem resilience
No full textThe resilience of macrobenthic communities to environmental stress depends upon the vulnerability, adaptability and connectivity of species. Recent studies suggest that the function(s) species perform may be more influential in driving community response to change than the more traditional measures of abundance and occurrence. Species that perform similar functions within a community theoretically give rise to redundancy, an important attribute of resilience. This thesis assesses the potential for functional redundancy in coastal macrobenthic communities by comparing the degree of sharing of specific functional traits, patterns of abundance and spatial distribution to provide insight into the potential for resilience. The research is focused on the functional diversity of a species rich macrobenthic community from a large intertidal area in the Kaipara Harbour, New Zealand. 400 macrofaunal and 360 sediment cores were collected using a newly developed hierarchical sampling grid covering an area of 300,000 m². This resulted in a data set consisting of 115 taxa and 23,682 individuals and 360 observations of sediment grain size and chlorophyll a. Linking species attributes such as body type, size, feeding mode, and living depth, produced 26 species functional groups that characterised important functional attributes of the macrobenthic community. These attributes relate to ecosystem functions associated with sediment biogeochemistry, stability and resilience to disturbance. Redundancy was assessed within these functional groups (ranging from 1-13 species per functional group) considering both occurrence and abundance in their spatial distribution. Various levels of redundancy were identified for different functional groups, for example, functional groups characterised by small deposit-feeding polychaetes encompassed high redundancy, whilst functional groups consisting of large suspension-feeding, highly mobile bivalves maintained low redundancy. Nevertheless, the latter functional group does contribute considerably to abundance despite its low redundancy. The spatial patterns exhibited by different functional groups (identified by correlograms using Moran’s I) were used to provide insights to connectivity and exposure of the functional group to localised disturbance. A range of spatial patterns were apparent, reflecting small-scale homogeneity to large-scale heterogeneity with spatial arrangements including gradients and distinct patches. Density maps showed that some functional groups, such as tube worms and large mobile suspension-feeding bivalves, showed strong and opposing spatial distributions, separated by clear boundaries. Canonical correspondence analyses indicated that the measured environmental variables were not important drivers of the spatial distribution of functional groups. Thus, either biological interactions between functional groups are the driving force of spatial diversity or this sampling strategy failed to measure relevant environmental parameters. These findings emphasise a role for spatial variation in functional diversity and species redundancy in structuring community resilience. Understanding the functional roles of species, the diversity of these functions and associated biological interactions, is essential for evaluating biodiversity and resilience
Neonatal thrush of newborns: Oral candidiasis?
No full textAbstract
Objectives: Neonatal thrush, also called oral candidiasis, is commonly a clinical diagnosis based on white patches on oral mucosal surfaces. Candida albicans is often associated with it. This clinical study aimed to investigate the presence of C. albicans among newborns with or without clinical findings of candidiasis on oral mucosa. Another aim was to investigate how thrush responded to current therapy by acidic liquids such as lingonberry or lemon juice.
Material and methods: Swipe samples were collected from 32 healthy, full‐term infants younger than 12 months with or without white patches on oral mucosa. Clinical diagnosis of thrush was made by a community nurse based on thick and yellowish white patches. The routine therapy was oral lingonberry or lemon juice or soda water. Disappearing of patches was controlled by a phone call about 2 weeks after the baseline. Both parents and nurses gave background factors by filling a questionnaire.
Results: One (3%) infant without clinical signs was diagnosed with Candida parapsilosis, none with C. albicans. Thrush resembling candidiasis was diagnosed clinically in four (12.5%) children. Three out of four parents reported persisting findings after 2 weeks. Only the maternal mastitis and use of antibiotics were significantly associated with thrush (p = .001). C. albicans was not discovered from babies with clinical thrush.
Conclusions: Aetiology of the white patches remained unclear. The current way of treating them with acidic liquids is not efficient. Additional studies are needed
beta-diversity and species accumulation in antarctic coastal benthos: influence of habitat, distance and productivity on ecological connectivity.
No full textHigh Antarctic coastal marine environments are comparatively pristine with strong environmental gradients, which make them important places to investigate biodiversity relationships. Defining how different environmental features contribute to shifts in beta-diversity is especially important as these shifts reflect both spatio-temporal variations in species richness and the degree of ecological separation between local and regional species pools. We used complementary techniques (species accumulation models, multivariate variance partitioning and generalized linear models) to assess how the roles of productivity, bio-physical habitat heterogeneity and connectivity change with spatial scales from metres to 100's of km. Our results demonstrated that the relative importance of specific processes influencing species accumulation and beta-diversity changed with increasing spatial scale, and that patterns were never driven by only one factor. Bio-physical habitat heterogeneity had a strong influence on beta-diversity at scales 40 km. Our analysis supports the emphasis on the analysis of diversity relationships across multiple spatial scales and highlights the unequal connectivity of individual sites to the regional species pool. This has important implications for resilience to habitat loss and community homogenisation, especially for Antarctic benthic communities where rates of recovery from disturbance are slow, there is a high ratio of poor-dispersing and brooding species, and high biogenic habitat heterogeneity and spatio-temporal variability in primary production make the system vulnerable to disturbance. Consequently, large areas need to be included within marine protected areas for effective management and conservation of these special ecosystems in the face of increasing anthropogenic disturbance
Standardizing Care to Prevent Oral Thrush in the Neonatal Intensive Care Unit: A Needs Assessment
No full textWhile term babies can develop oral thrush with no issues, premature infants are at a higher risk for increased susceptibility to more invasive infections. The oral mucosa is home to hundreds of microbial species, including bacteria, fungi, archaea, protozoa, and bacteriophages (Baumgardner, 2019). Candida albicans is an opportunistic pathogen that commonly attaches to oral mucosa and is the most common cause of oral thrush (Vila et al., 2020). A 51-bed NICU that lacks a formal oral thrush guideline for neonates, hindering staff in the prevention and management of oral thrush. A needs assessment was conducted at a Level IV NICU in Utah to evaluate the feasibility and useability of a NICU oral thrush guideline. This scholarly project was initiated by addressing an issue in the NICU related to oral thrush. First, an extensive literature review was conducted to evaluate the current best practices. A survey was created and distributed to stakeholders to assess the feasibility and potential useability of an oral thrush guideline. External benchmarking was conducted to evaluate various practices across Utah and internationally. A retrospective chart review from January 2024 to December 2024 was completed to assess the previous incidences of oral thrush in the NICU. Lastly, a strengths, weaknesses, opportunities, and threats (SWOT) analysis was conducted to examine the feasibility and useability of the oral thrush guidelines. The chart review found that 8.1% of infants admitted to the NICU had thrush and received treatment. Of those infants that had thrush, 21.4% required additional treatment after the initial oral thrush infection. The survey indicated that stakeholders agreed there is a need for an oral thrush guideline. Survey results were collected using REDCap, with the total number of surveys (n=89), which is a 26% return rate of the stakeholders. The majority of the survey was from registered nurses (66.3%). The SWOT analysis highlighted the strengths of professional support and weaknesses of time limitations and increased learning requirements. This needs assessment used literature review, a survey, discussions, and the development of a SWOT analysis to demonstrate the usability and feasibility of an oral thrush guideline. This project would benefit from a continued effort to implement the oral thrush guideline and utilize rapid plan, do, study, act (PDSA) cycles to address discrepancies
Murder on the mountain: author talk with Peter J. Wosh
No full textAuthor talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.
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