7 research outputs found

    ESTIMATION OF PARTIAL FREQUENCY RESPONSE FUNCTIONS OF A PARAMETRICALLY EXCITED FLEXIBLE MULTIBODY SYSTEM

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    ABSTRACT Flexible multibody system simulation allows for fast and adequate investigation of the dynamics of mechanical systems. But in case of a system response with large deformations the time response does not uncover the causes, i. e. the resonances of the system. The identification of the systems eigenfrequencies gives more insight in resonance phenomena, but in case of periodic time-variant systems the often used snap-shot-eigenfrequencies do not reveal the real system dynamics, which has to be described by more than only one frequency response function. Based on the formulation of a flexible multibody system and the theory of ordinary linear periodic differential equations, partial frequency response functions, describing the real characteristics of a periodic system, are calculated and compared to the snapshot-frequency response functions. NOMENCLATURE A orientation matrix (sec. 2), system matrix (sec. 3) E youngs modulus H Hooke matrix (sec. 2), frf matrix (sec. 3-5) J Jacobian matrix L differential operator M, D, K mass, damping, stiffness matri

    Konzepte, Methoden und Anwendungen der Sozialen Netzwerkanalyse in Forschung und Entwicklung

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    Title and Table of Contents 1 Introduction 1 1.1 Goal 1 1.2 Method 2 1.3 Overview 5 2 Perceptions of Knowledge, Knowledge Society and Knowledge Management 9 2.1 The Emerging Knowledge Society 9 2.2 Perspectives, Conceptions and Social Construction of Knowledge 15 2.3 Constitutional Conditions of Knowledge Management and its Institutionalization 30 2.4 Today s Knowledge Management Practices and Future Perspectives Expert Views 38 2.5 Communication and Management of Knowledge 50 3 Communities and Social Networks in Organizational Knowledge Communication 63 3.1 Organizational Knowledge Communication 63 3.2 The Role of Communities for Knowledge Communication Expert Views 71 3.3 Sociological Perspectives and Limits of the Community Concept Classics revisited 75 3.4 Knowledge Communities, Communities of Practice, Knowledge Networks Expert Views 85 3.5 Social Network Perspective and Knowledge 94 4 Social Networks and the Generation of Innovations 103 4.1 The Generation of Innovations in the Knowledge Society 103 4.2 Knowledge Management in R&D; Expert Views 109 4.3 Networks and Knowledge Communication in R&D; Environments 114 4.4 Institutionalization of Knowledge Transfer in R&D;: Networks as Intermediaries 129 4.5 Entrepreneurial Social Networks 135 4.6 Limits of the Network Concept 139 5 Social Network Analysis as a Knowledge Management Tool 145 5.1 Introduction to Social Network Analysis 145 5.2 Social Network Analysis as a Knowledge Management Tool Method Development 153 5.3 Application of Social Network Analysis as a Knowledge Management Tool Basic Steps 158 5.4 Case Study 1 (Pre-test Study): Leveraging Organizational Expertise 173 5.5 Case Study 2 (Evaluation Study): Entrepreneurial Network Evolution 188 5.6 Case Study 3 (Application Study): Inter-organizational Knowledge Community Building 210 5.7 Leveraging Knowledge Communication Networks Approaches to Interpretations and Interventions 227 6 Conclusion and Outlook 241 6.1 Synopsis 241 6.2 Research Contribution 244 6.3 Further Research 246 Bibliography 249The paradigm of social network analysis (SNA) has become widely recognized as a potential approach to analyze, evaluate, and influence communication processes. The author argues that SNA proves useful both as a theoretical concept and a practical tool for knowledge communication in research and development (R&D;). The context of innovative knowledge generation in organizational R&D; environments is introduced very broadly with an extensive reference to the existing literature. The pragmatic approach of networks is outlined as a powerful concept to grasp the social relationships between individuals as well as between social aggregates for conceptual and analytical purposes with striking simplicity. Based on three case studies, methods of SNA are simplified and vividly illustrated according to their basic steps to meet practical needs and show their usefulness for business practice. Moreover, the book provides illustrative examples for interventions and follow-up activities to improve processes of organizational knowledge communication based on SNA. (Available also as: Müller-Prothmann, Tobias, 2006: Leveraging Knowledge Communication for Innovation. Framework, Methods and Applications of Social Network Analysis in Research and Development. Series: European University Studies, Series V: Economics and Management, Vol. 3189. Frankfurt a. M., Berlin, Bern, Bruxelles, New York, Oxford, Wien. XIV, 278 pp., num. tables and graphs. DE-ISBN: 3-631-55165-7 / US-ISBN: 0-8204-9889-0.)Die Soziale Netzwerkanalyse (SNA) erfährt eine hohe Aufmerksamkeit als Methode zur Analyse, Bewertung und Beeinflussung von Kommunikationsprozessen. Insbesondere eignet sie sich als theoretisches Konzept und praktisches Werkzeug zur Analyse und Unterstützung der Wissenskommunikation in Forschung und Entwicklung. In dieser Arbeit wird der Kontext innovativer Wissensgenerierung in Forschungs- und Entwicklungsumgebungen auf breiter Literaturbasis eingeführt. Im Anschluss wird der pragmatische Netzwerkansatz als mächtiges Konzept zur Erfassung von sozialen Beziehungen zwischen Individuen und sozialen Aggregaten (Gruppen, Abteilungen, Organisationen etc.) ausführlich dargestellt. Anhand von drei Fallstudien werden die Soziale Netzwerkanalyse und ihre grundlegenden Methoden für die praktische Anwendung dargestellt. Darüber hinaus bietet die Arbeit Beispiele für Interventionen und Follow-up-Aktivitäten zur Verbesserung der organisationalen Wissenskommunikation auf Basis der Sozialen Netzwerkanalyse. (Auch als gedrucktes Buch erhältlich: Müller-Prothmann, Tobias, 2006: Leveraging Knowledge Communication for Innovation. Framework, Methods and Applications of Social Network Analysis in Research and Development. Series: European University Studies, Series V: Economics and Management, Vol. 3189. Frankfurt a. M., Berlin, Bern, Bruxelles, New York, Oxford, Wien. XIV, 278 pp., num. tables and graphs. DE-ISBN: 3-631-55165-7 / US-ISBN: 0-8204-9889-0.

    The Globin Gene Family in Arthropods: Evolution and Functional Diversity

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    Globins are small heme-proteins that reversibly bind oxygen. Their most prominent roles in vertebrates are the transport and storage of O2 for oxidative energy metabolism, but recent research has suggested alternative, non-respiratory globin functions. In the species-rich and ecologically highly diverse taxon of arthropods, the coppercontaining hemocyanin is considered the main respiratory protein. However, recent studies have suggested the presence of globin genes and their proteins in arthropod taxa, including model species like Drosophila. To systematically assess the taxonomic distribution, evolution and diversity of globins in arthropods, we systematically searched transcriptome and genome sequence data and found a conserved, widespread occurrence of three globin classes in arthropods: hemoglobin-like (HbL), globin X (GbX), and globin X-like (GbXL) protein lineages. These globin types were previously identified in protostome and deuterostome animals including vertebrates, suggesting their early ancestry in Metazoa. The HbL genes show multiple, lineage-specific gene duplications in all major arthropod clades. Some HbL genes (e.g., Glob2 and 3 of Drosophila) display particularly fast substitution rates, possibly indicating the evolution of novel functions, e.g., in spermatogenesis. In contrast, arthropod GbX and GbXL globin genes show high evolutionary stability: GbXL is represented by a single-copy gene in all arthropod groups except Brachycera, and representatives of the GbX clade are present in all examined taxa except holometabolan insects. GbX and GbXL both show a brain-specific expression. Most arthropod GbX and GbXL proteins, but also some HbL variants, include sequence motifs indicative of potential N-terminal acylation (i.e., N-myristoylation, 3C-palmitoylation). All arthropods except for the brachyceran Diptera harbor at least one such potentially acylated globin copy, confirming the hypothesis of an essential, conserved globin function associated with the cell membrane. In contrast to other animals, the fourth ancient globin lineage, represented by neuroglobin, appears to be absent in arthropods, and the putative arthropod orthologs of the fifth metazoan globin lineage, androglobin, lack a recognizable globin domain. Thus, the remarkable evolutionary stability of some globin variants is contrasted by occasional dynamic gene multiplication or even loss of otherwise strongly conserved globin lineages in arthropod phylogeny
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