34,111 research outputs found
Photograph: Group Portrait, W.H. Alexander Tailoring Class
Image of two rows of men and a woman sitting and standing, holding tailoring tools and a sign. Sign: W.H. ALEXANDER TAILORING CLASS TERRELL TEX 2-28. No year visible. One of 156 black and white photographs by R. Lee Thomas, an African American photographer active in the early twentieth century in the southern United States. Thomas’ work provides photographic documentation of southern black social life, primarily religious and labor groups, circa 1946-1949. The majority of the photographs depict groups from Birmingham, Alabama, and adjacent areas. His imprint contains the caption: Made by R. Lee Thomas, Mound Bayou, Mississippi, The Oldest Negro Town in America.https://digitalcommons.unf.edu/rthomas/1034/thumbnail.jp
William R. Dickinson letter to Thomas Rotch, Steubenville, June 2nd 1817
William Dickinson asks Thomas Rotch to forward a letter to Alexander Skinner; he mentions that a note for $700 is due, but Dickinson does not know where Skinner is living. Skinner and Rotch had a falling out around 1816 over Skinner's mismanagement of Rotch's country store. He left Kendal for Loudonville, Ohio in 1817. 7.8" x 10.1" (19.2 by 25.6 cm
Authors on the Hill presents: Thomas R. Martin
Thomas R. Martin is the Jeremiah O’Connor Professor in Classics. As an undergraduate he studied abroad in Rome and earned his AB degree at Princeton University; as a graduate student he studied abroad in Athens and earned his PhD at Harvard University. He currently teaches courses on ancient Greek and Latin language and literature, Alexander the Great and Asia, and democracy and rhetoric. His scholarly publications concern a range of topics in ancient Greek and Latin historical authors and Greek and Roman history. Prof. Martin is also one of the founders of the online Perseus Project and the author of its overview of ancient Greek history. He has appeared in a number of video and recorded programs on ancient Greece and Rome. [See the list on pp. 11-12 in his current CV.] His most recent book is Phocion: Good Citizen in a Divided Democracy (Yale Univ. Press, 2024). Written for readers who are interested in the early development of democracy, but who are not specialists in ancient history, the book explores the lessons that we can today learn from thinking about the long and ultimately disastrous political career of the Athenian leader Phocion (ca. 402-318 BCE). Prof. Martin asks how and why Phocion initially became famous and influential among his fellow citizens at Athens, but then ended up being blamed and executed as a national traitor during the period of Athenians’ fall from being a leading international power and of the violent fracturing of their renowned “direct democracy.”https://crossworks.holycross.edu/aoth/1022/thumbnail.jp
The Gospel of Thomas and the earliest texts of the synoptic gospels
Research on the Gospel of Thomas in the last quarter of a
century has made it clear that the origins of this apocryphal gospel
cannot
be
satisfactorily explained from a single point of view. The
author thus suggests that Thomas
be
understood as a growing collection
of sayings which originated in various places and languages, with some
logia being added to the collection after its inception. While this
suggestion is by no means new, there have been few extensive attempts
to study Thomas from such a presupposition.
Due to the need for a control group, only the logia which have
rather close parallels to the Synoptic gospels are investigated. Verbal and textual affinities are noted between these logia and the earliest texts of the Gospels (the Coptic versions, the Diatessaron, the
Old Syriac version, and other early versions and Christian writings).
Various degrees of probable contact between each logion and these
texts are assigned.
The results of this study give some idea as to the place of
origin, the original language, and the approximate date at which certain logia were added to the collection. Those sayings which show a
closer affinity to the Diatessaron, the Old Syriac version, or other
Syrian writings may
be
considered as having been added to the sayings
collection as it circulated in its earliest form, possibly in a Semitic language. Other logia which show no signs of awareness of a
Syrian reading, but which are similar to variants found in the Coptic
versions or other Egyptian texts, may well have originated in Egypt
and been added to the collection at a later stage. These results,
however, must await verification by those who might approach Thomas
from related, but different, perspectives
Lamar Alexander
Governor and later, U.S. Education Secretary, Lamar Alexander received an honorary degree in 1980. The back reads: Tenn. Gov. Lamar Alexander receives honorary (LLD) degree [at] Commencement 1980. (L - R) Pres. Dr. EArl Mezoff, Dr. Paul Keller, Gov. Alexander, The Hon. Thomas Hull and Dr. Estel C. Hurley
Park City, May 1966. L- R: Tim Heydon, Activities Director; Woody Anderson; Lowell Thomas, holding Lowell Thomas Classic Race trophy.
Photo taken at Park City, May 1966. L- R: Tim Heydon, Activities Director; Woody Anderson; Lowell Thomas, holding Lowell Thomas Classic Race troph
Molecular and cellular basis of the internalization of "Bartonella henselae" by human endothelial cells
The facultative intracellular bacterium Bartonella henselae enters human
endothelial cells either passively by conventional phagocytosis or actively by a
pathogen-triggered process known as invasome-mediated internalization. The latter
involves the formation of a cell-surface-associated bacterial aggregate, which is
subsequently engulfed by host cell membranes eventually resulting in its complete
internalization.
Recent work indicated that invasome formation of B. henselae depends on its
VirB/VirD4 T4SS.
This work describes that the VirB/VirD4 T4SS of B. henselae injects a cocktail
of seven effector proteins into endothelial host cells to subvert cellular functions and
that one of these translocated effector proteins, BepG, mediates the sustained
cytoskeletal changes leading to invasome formation. Moreover, this work indicates the
existence of two non-redundant pathways to promote invasome formation, one of
which is governed by the action of BepG and another one, involving further Bep
proteins, which is BepG-independent.
On the host cell side, Rho-family small GTPases Cdc42 and Rac1, but not RhoA
are shown to be required for invasome-mediated internalization. Furthermore, it is
shown that invasome formation leads both to the rearrangement of pre-existing F-actin
fibers and to localized actin polymerization enriched for Arp2/3, which occurs in a
Scar1/WAVE-dependent manner. Finally, this work provides evidence that after
complete internalization the invasome membranes do not fuse with Lamp-1 positive
lysosomes, indicating that invasome-mediated invasion represents a novel mechanism
allowing the uptake of bacteria without entering the endocytic-lysosomal pathway.
Importantly, this is the first report, which attributes the orchestrated action of
more than one effector protein of B. henselae to a known VirB/VirD4 T4SS-dependent
phenotype, namely invasome formation, which represents a multifacetted example for
the complexity of host cell subversion by a bacterial pathogen
Group of veterans of Thomas-Field Co., Dec. 20, 1948
Group of veterans of Thomas-Field Co., Dec. 20, 1948, H.R. Alexander 2nd from right,b&w. Back reads: Thomas Field veterans, Thomas Field & Co., December 20, 1948 Thomas Field Co. was a wholesale dry goods firm that had an office in Charleston. H. R. Alexander is second from right.https://mds.marshall.edu/helen_alexander_papers/1046/thumbnail.jp
fgui: A Method for Automatically Creating Graphical User Interfaces for Command-Line R Packages
The fgui R package is designed for developers of R packages, to help rapidly, and sometimes fully automatically, create a graphical user interface for a command line R package. The interface is built upon the Tcl/Tk graphical interface included in R. The package further facilitates the developer by loading in the help files from the command line functions to provide context sensitive help to the user with no additional effort from the developer. Passing a function as the argument to the routines in the fgui package creates a graphical interface for the function, and further options are available to tweak this interface for those who want more flexibility.
Letter from R. Bullard to Alden Partridge, 23 July 1828
R. Bullard writes from Camden, South Carolina, to Alden Partridge in Middletown, Connecticut; he is no longer the guardian of Isaac Alexander and Henry Alexander and has forwarded Partridge's letter regarding money due on their accounts (from their time as students at Partridge's academy) to Thomas P. Evans .Transcription by Joseph Byrne. Transcriptions may be subject to error
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