17 research outputs found
The shannon capacity on C(n,k)
No full textThis thesis focuses on a problem formulated by Claude Shannon named the Shannon capacity. This problem is about information rate per time unit over a noisy channel. The noisy channel is here represented by a graph. We specifically focus on a class of circulant graphs that are denoted by C(n,k) with vertex set z/nz, where all vertices are connected with the k-1 vertices before and after it. We will discuss upper bounds that were found for the Shannon capacity and how C(n,k) behaves with these upper bounds. After that we will focus on multiple ways to calculate lower bounds for the Shannon capacity of . For these three search methods will be used. These are exhaustive searching for optimal values, optimal ways to make packagings and solutions created by using a special form. As last the answers will be discussed by combining the upper and lower bounds for C(n,k). From this conclusions are drawn after which some possibilities will be given for further research. Applied Mathematic
Qoheleth's Allusions to Abel: Reading Qoheleth as a Contemplation on the Story of the First Unjustly Murdered Human
No full textIn Qoheleth’s reflection on the state of human life, he finds that life is often unfair. This leads him to the conclusion that “all is hebel” (1:2). Hebel is also the name of the first murder victim in the Hebrew bible: Abel, whose birth and death is described in Genesis 4. This paper, using the approach of inner-biblical allusion, argues that not only the term hebel, but also the phrases rǝʿût/raʿyôn rûaḥ and rōʿeh eḥād can be understood as allusions to Abel. Specifically, this paper argues for a new reading of the phrase rōʿeh eḥād (usually translated as “one/a/any shepherd”), as “the first shepherd,” as a direct allusion to Abel. This paper suggest that the author of Qoheleth alludes to Abel in order to contemplate and reflect on the story of the first human who was unjustly murdered as a part of his broader reflection on human life and its injustices
Diepe ontzwaveling van Kuwait straight run gasolie in een trickle bed reactor
No full textDocument(en) uit de collectie Chemische ProcestechnologieDelftChemTechApplied Science
Intergenerational digital storytelling with older adults (Webinar Series on Ageing)
No full textIntergenerational programs are social vehicles that create purposeful and ongoing exchange of resources and learning among older and younger generations. This presentation highlights the work of PADSIP (Positive Ageing Digital Storytelling Intergenerational Project) which has been operational for over 15 years. The presentation highlights elements of such programs that are transformative and impactful for participants and the community. It also highlights the potential for such programs to change stereotypes and foster better understanding between the generations.
Held 2 May 202
Electron acceleration sites in a large-scale coronal structure
No full textRadio observations and interplanetary particle measurements have
shown that even in the absence of conspicuous violent processes in the low
atmosphere (such as Hα flares) electrons are accelerated in the corona, most
likely at higher altitudes than during flares (≥0.5 R above the
photosphere). The paper presents direct evidence on the acceleration sites from
a case study of radio, visible light and soft X-ray observations: electrons are
repeatedly accelerated in a large-scale coronal structure which is identified
with a streamer in coronographic observations. Energy is simultaneously
released in an active region near the base of the structure and at a height of
∼1 R , over several hours before the large-scale structure erupts. Energy
input is observed in at least two emerging active regions underneath the
streamer. The coronal configuration is three-dimensional, overlying a whole
quadrant of the Sun. It is argued that the observations trace multiple sites of
energy release presumably in current sheets embedded within the streamer, in
agreement with scenarios developed for the acceleration of electrons seen in
the corona and at 1 AU, and for the evolution of large-scale coronal structures
towards eruption
Intergenerational Programs in Aged Care Settings (Webinar Series on Ageing)
No full textIntergenerational programs are social vehicles that create purposeful and ongoing exchange of resources and learning among older and younger generations. This presentation will highlight the work of PADSIP (Positive Ageing Digital Storytelling Intergenerational Project) over the past 15 years. A panel of speakers will discuss elements of the project that are transformative and impactful for participants and the community. The panel will also highlight the potential for such programs to change stereotypes and foster better understanding between the generations
ERF5 and ERF6 play redundant roles as positive regulators of JA/Et-mediated defense against botrytis cinerea in arabidopsis
No full textCopyright @ 2012 Moffat et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.The ethylene response factor (ERF) family in Arabidopsis thaliana comprises 122 members in 12 groups, yet the biological functions of the majority remain unknown. Of the group IX ERFs, the IXc subgroup has been studied the most, and includes ERF1, ERF14 and ORA59, which play roles in plant innate immunity. Here we investigate the biological functions of two members of the less studied IXb subgroup: ERF5 and ERF6. In order to identify potential targets of these transcription factors, microarray analyses were performed on plants constitutively expressing either ERF5 or ERF6. Expression of defense genes, JA/Et-responsive genes and genes containing the GCC box promoter motif were significantly upregulated in both ERF5 and ERF6 transgenic plants, suggesting that ERF5 and ERF6 may act as positive regulators of JA-mediated defense and potentially overlap in their function. Since defense against necrotrophic pathogens is generally mediated through JA/Et-signalling, resistance against the fungal necrotroph Botrytis cinerea was examined. Constitutive expression of ERF5 or ERF6 resulted in significantly increased resistance. Although no significant difference in susceptibility to B. cinerea was observed in either erf5 or erf6 mutants, the erf5 erf6 double mutant showed a significant increase in susceptibility, which was likely due to compromised JA-mediated gene expression, since JA-induced gene expression was reduced in the double mutant. Taken together these data suggest that ERF5 and ERF6 play positive but redundant roles in defense against B. cinerea. Since mutual antagonism between JA/Et and salicylic acid (SA) signalling is well known, the UV-C inducibility of an SA-inducible gene, PR-1, was examined. Reduced inducibilty in both ERF5 and ERF6 constitutive overexepressors was consistent with suppression of SA-mediated signalling, as was an increased susceptibility to avirulent Pseudomonas syringae. These data suggest that ERF5 and ERF6 may also play a role in the antagonistic crosstalk between the JA/Et and SA signalling pathways.This work was funded by the Biotechnology and Biological Sciences Research Council (BBSRC) UK (studentship BBS/S/B/2003/12908 and BBS/S/K/2003/10126
The prognostic role of lymphovascular invasion and lymph node metastasis in perihilar and intrahepatic cholangiocarcinoma
No full textIntroduction: Cholangiocellular carcinoma (CCA) is an aggressive malignancy with a dismal prognosis. Among curative treatment options for CCA, radical surgical resection with extrahepatic bile duct resection, hepatectomy and en-bloc lymphadenectomy are considered the mainstay of curative therapy. Here, we aimed to identify prognostic markers of clinical outcome in CCA-patients who underwent surgical resection in curative intent.Material and methods: Between 2011 and 2016, 162 patients with CCA (perihilar CCA (pCCA): n = 91, intrahepatic CCA (iCCA): n = 71) underwent surgery in curative intent at our institution. Preoperative characteristics, perioperative data and oncological follow-up were obtained from a prospectively managed institutional database. The associations of overall-(OS) and disease-free-survival (DFS) with clinico-pathological characteristics were assessed using univariate and multivariable cox regression analyses.Results: The median OS and DFS were 38 and 36 months for pCCA and 25 and 13 months for iCCA, respectively. Lymphovascular invasion (LVI) and lymph node metastasis as well as surgical complications as assessed by the comprehensive complication index (CCI) and tumor grading were independently associated with OS for the pCCA (LVI; RR = 2.36, p = 0.028; CCI; RR = 1.04, p <0.001) and iCCA cohorts (N-category; RR = 3.21, p = 0.040; tumor grading; RR = 3.75, p = 0.013; CCI, RR = 4.49, p = 0.010), respectively. No other clinical variable including R0-status and Bismuth classification was associated with OS.Conclusion: Major liver resections for CCA are feasible and safe in experienced high-volume centers. Lymph node metastasis and LVI are associated with adverse clinical outcome, supporting the role of systematic lymphadenectomy. The assessment of LVI may be useful in identifying high-risk patients for adjuvant treatment strategies. (C) 2019 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.</p
The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma
No full textThe oncological role of the density of nerve fibers (NFs) in the tumor microenvironment (TME) in intrahepatic cholangiocarcinoma (iCCA) remains to be determined. Therefore, data of 95 iCCA patients who underwent hepatectomy between 2010 and 2019 was analyzed regarding NFs and long-term outcome. Extensive group comparisons were carried out and the association of cancer-specific survival (CSS) and recurrence-free survival (RFS) with NFs were assessed using Cox regression models. Patients with iCCA and NFs showed a median CSS of 51 months (5-year-CSS = 47%) compared to 27 months (5-year-CSS = 21%) in patients without NFs (p = 0.043 log rank). Further, NFs (hazard ratio (HR) = 0.39, p = 0.002) and N-category (HR = 2.36, p = 0.010) were identified as independent predictors of CSS. Patients with NFs and without nodal metastases displayed a mean CSS of 89 months (5-year-CSS = 62%), while patients without NFs or with nodal metastases but not both showed a median CCS of 27 months (5-year-CSS = 25%) and patients with both positive lymph nodes and without NFs showed a median CCS of 10 months (5-year-CSS = 0%, p = 0.001 log rank). NFs in the TME are, therefore, a novel and important prognostic biomarker in iCCA patients. NFs alone and in combination with nodal status is suitable to identify iCCA patients at risk of poor oncological outcomes following curative-intent surgery
