1,720,954 research outputs found
Precision Recovery in Interventional Pulmonology: A Randomized Controlled Trial Comparing Propofol Target-Controlled Infusion versus Sevoflurane Inhalation on Emergence Kinetics and Hemodynamic Stability
Full text linkBackground: Achieving a rapid and high-quality recovery is a cornerstone of modern procedural sedation, particularly in high-turnover ambulatory bronchoscopy suites. Patients presenting for bronchoscopy often exhibit significant pulmonary pathology, including ventilation-perfusion mismatch, which may theoretically impede the alveolar washout of volatile anesthetics. This study aimed to compare the recovery kinetics, hemodynamic stability, and adverse event profiles of Propofol Target-Controlled Infusion (TCI) utilizing the Schnider model versus standard Sevoflurane inhalational anesthesia.
Methods: In this single-blind, prospective, randomized controlled trial, 36 adult patients (ASA I–III) undergoing elective flexible bronchoscopy were recruited. Participants were randomly allocated to receive either Propofol TCI (Group P; Schnider model, target effect-site concentration 4–6 micrograms/mL) or Sevoflurane (Group S; 2 volume percent). The depth of anesthesia was strictly titrated using Bispectral Index (BIS) monitoring to maintain a range between 40 and 60. The primary outcome was recovery time, defined as the duration from anesthetic discontinuation to eye-opening upon verbal command. Secondary outcomes included intraoperative hemodynamic stability (Mean Arterial Pressure and Heart Rate), BIS values at the moment of emergence, and the incidence of postoperative nausea and vomiting (PONV).
Results: The Propofol TCI group demonstrated a statistically significant reduction in recovery time (9.72 ± 1.52 minutes) compared to the Sevoflurane group (12.11 ± 1.49 minutes; p < 0.001). Procedural duration was comparable between groups (p = 0.412), eliminating surgical time as a confounding variable. Group P exhibited superior hemodynamic stability, with significantly less deviation from baseline Mean Arterial Pressure at 10 and 15 minutes into the procedure (p < 0.05). Furthermore, BIS values at the moment of eye-opening were significantly higher in Group P (88.4 ± 4.2) compared to Group S (82.1 ± 5.1; p = 0.021), suggesting a distinct emergence neurophysiology. The incidence of PONV was notably lower in the Propofol group (5.5 percent) compared to the Sevoflurane group (22.2 percent).
Conclusion: Propofol target-controlled infusion facilitates significantly faster emergence and greater hemodynamic stability than Sevoflurane in patients undergoing flexible bronchoscopy. The pharmacokinetic independence of Propofol from pulmonary gas exchange offers a distinct physiological advantage in this specific patient population. These findings support the adoption of TIVA-TCI as the standard of care for optimizing throughput in interventional pulmonology
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Perbandingan Status Nutrisi Minggu Pertama pada Pasien Pascacedera Otak Traumatik Sedang dan Berat yang Dirawat di RSUP Dr. Hasan Sadikin Bandung Dinilai dengan Subjective Global Assessment (SGA)
No full textLatar Belakang dan Tujuan: Penilaian status nutrisi merupakan hal vital untuk menentukan rencana pemberian nutrisi dan memperbaiki luaran pasien dengan cedera otak traumatik (COT). Pada pasien COT terjadi hipermetabolisme, hiperkatabolisme, dan intoleransi glukosa yang dapat mempengaruhi luaran pasien. Penilaian status gizi dilakukan dengan Subjective Global Assessment (SGA). Tujuan penelitian ini adalah untuk membandingkan status nutrisi antara pasien COT sedang dan berat yang dinilai dengan SGA.
Subjek dan Metode: Penelitian observasional analitik cross sectional ini dilakukan pada 22 pasien COT yang dirawat di RSUP Dr Hasan Sadikin Bandung sejak November 2016 - Juli 2017, yang dibagi menjadi 2 kelompok, yaitu COT sedang dan berat. Status nutrisi subjek penelitian dinilai dengan SGA selama 7 hari. Analisis data dilakukan dengan Chi Square, Kolmogorof-Smirnof dan Exact Fisher.
Hasil: Terdapat perbedaan status nutrisi yang signifikan antara kelompok COT sedang dan berat pada hari perawatan ke-6 dan 7, dimana lebih banyak didapatkan malnutrisi berat pada kelompok COT berat (p0,05).
Simpulan: Pada penelitian ini malnutrisi lebih banyak terjadi pada pasien dengan COT berat, disebabkan oleh perlambatan pemberian nutrisi akibat disfungsi gastrointestinal yang terjadi pada pasien COT berat sehingga diperlukan strategi pemberian nutrisi khusus pada kelompok COT berat.
Comparison of a One Week Nutritional Status between Moderate and Severe Traumatic Brain Injury Patient in Dr. Hasan Sadikin General Hospital Assessed with Subjective Global Assessment (SGA)
Background and Objective: Assessment of nutritional status is vital in determining nutritional plans and improving outcomes of traumatic brain injury (TBI) patients. Hypermetabolism, hypercatabolism, and glucose intolerance occur in patients with TBI can affect its outcome. The used nutritional status assessment is Subjective Global Assessment (SGA). The aim of this study was to compare nutritional status in moderate and severe TBI patients assesed with SGA.
Subject and Method: This cross sectional observational analytic study was conducted on 22 TBI patients treated in RSUP DR. Hasan Sadikin Bandung since November 2016 - July 2017, divided into 2 groups, moderate and severe TBI. Assessment of SGA in study subjects was conducted for 7 days. Data was analyzed with Chi Square, Kolmogorof-Smirnof and Exact Fisher test.
Results: This study showed a significant difference in nutritional status between moderate and severe TBI groups during the 6th and 7th treatment days, whereas more severe malnutrition was found in the severe TBI group (p 0.05).
Conclusion: Compares to patients with moderate TBI, malnutrition is more prevalent in patients with severe TBI, because of delayed of nutrient delivery due to gastrointestinal dysfunction occurring in severe TBI patients requiring specific nutritional strategies in severe TBI group
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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