1,720,958 research outputs found
Beta cell function and long term health into adulthood in classic transient neonatal diabetes.
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
beta-cell dysfunction in classic transient neonatal diabetes is characterized by impaired insulin response to glucose but normal response to glucagon
No full textOBJECTIVE— To investigate -cell function and the long-term health of four case subjects
presenting with chromosome 6–associated transient neonatal diabetes (TND).
RESEARCH DESIGNANDMETHODS — Two unrelated case subjects presenting with
paternal uniparental isodisomy of chromosome 6 (UPD6) and two siblings with a paternally
inherited duplication of 6q24 were studied. Three case subjects presented with neonatal diabetes
that recurred at 4–17 years, while diabetes was incidentally discovered in the other case subject
at 14 years of age. -Cell function was investigated after diabetes relapse by means of an oral
glucose tolerance test (OGTT), an intravenous glucose tolerance test (IVGTT), and glucagon
tests. The quantitative insulin sensitivity check index (QUICKI) was calculated from fasting
blood samples as an estimate of insulin sensitivity.
RESULTS— -Cell function was investigated at diabetes relapse in two case subjects: the
insulin response to both an OGTT and IVGTT was low, whereas the basal levels of C-peptide
were normal. No evidence of insulin resistance was found. Residual -cell function was further
explored by a glucagon test in all subjects at the age of 16–28 years and was found to be normal.
Final height was within the normal percentiles, whereas one case, who had been poorly controlled
since puberty, presented with diabetes-related microvascular complications.
CONCLUSIONS— In patients with chromosome 6–associated TND, the -cell is preserved
and able to secrete insulin through the stimulatory G protein pathway while exhibiting a specific
defect of insulin secretion after glucose stimulation. This form of diabetes can be managed with
insulin or diet, although new therapeutic agents (glucagon-like synthetic analogs) may prove
useful in the future. Lack of treatment leads to long-lasting hyperglycemia without the risk of
ketoacidosis but associated with microangiopathy in adult life
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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