1,720,987 research outputs found

    Evolution of the Gelasian (Pleistocene) slope turbidite systems of southern Marche (Peri-Adriatic basin, central Italy)

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    Examples of slope channels and canyons being diverted by structurally related sea-floor topography are commonly found both on the modern seabed and in the subsurface, in deep-water fold and thrust belts but their depositional histories have rarely been documented using examples from outcrop. The synthesis of outcrop (original geological field mapping at 1:10,000 scale) and subsurface data sets from the early Pleistocene stratigraphic succession of the Peri-Adriatic basin provides a window into the overall evolutionary pattern of large intraslope turbidite systems that, during the Gelasian (2.58–1.80 Ma), shed Apennine-derived clastic sediments into the adjacent deep-water basin. Trends from mapping and paleocurrent indicators converge to indicate that the sea-floor bathymetric expression of a thrust-related anticline, the north-trending Jesi-Nereto-Zaccheo structure, likely influenced the downslope transport direction of gravity flows and sediment dispersal pattern. During early and middle Gelasian time, coarse-grained turbidite deposition occurred on the western flank of the intraslope anticline by westerly sourced, northward-flowing turbidity currents, indicating that the opposing sea-floor topography was sufficient to cause the diversion of turbidite systems, forcing them to travel near parallel to the east-facing regional paleoslope for significant distances. By very late Gelasian time, the intraslope accommodation space on the western flank of the anticline had filled and turbidites were dispersed through dip-oriented conduits incising across the crest of the underlying structure

    Large-scale stratigraphic architecture and sequence analysis of an early Pleistocene submarine canyon fill, Monte Ascensione succession (Peri-Adriatic basin, eastern central Italy).

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    The Monte Ascensione succession (c. 2.65–2.1 Ma) is a well-exposed example of an exhumed submarine canyon fill embedded within slope hemipelagic mudstones. This gorge represented a long-lasting pathway for sediment transport and deposition and during the Gelasian delivered Apennine-derived clastic sediment to the adjacent Peri-Adriatic basin. A total of six principal lithofacies types, representing both canyon-confining hemipelagic deposits and canyon-filling turbidity current and masstransport deposits, can be delineated in the studied sedimentary succession. The canyon-fill deposits display a marked cyclic character and the component lithofacies succeed one another to form at least fifteen fining-upward stratal units, which are interpreted to represent high-frequency, unconformity- bounded depositional sequences. Variability in the vertical repetition of constituent lithofacies allows the identification of three basic styles of sequence architecture that can be interpreted in terms of differing positions along a conceptual down-canyon depositional profile. An integrated chronology, based on biostratigraphic data and on palaeomagnetic polarity measurements, strongly supports a one-to-one correlation between the sequence-bounding surfaces and oxygen isotope stages G2–78, suggesting that the most feasible sequence-engendering mechanism is that of orbitally dictated glacio-eustatic changes in sea level, which regulated timing of sediment storage on the shelf and its redistribution beyond the shelf edge. One of the most significant aspects of this study is the demonstration that processes occurring within upper slope canyons can be expected to be strongly influenced by variations in sea level; that is, the erosional and depositional features evident in these deposits can be strongly controlled by allocyclic processes rather than autocyclic or random processes

    La rete delle aree naturali protette e dei Siti Natura 2000

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    Il territorio del Centro Italia colpito dagli eventi sismici si caratterizza per una grande varietà di situazioni e contesti paesaggisticamente differenti, accomunati da un minuto alternarsi di insediamenti, infrastrutture e una matrice ambientale di fondo straordinariamente ricca di elementi di valore

    A method permissive to fixation and permeabilization for the multiparametric analysis of apoptotic and necrotic cell phenotype by flow cytometry

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    Annexin-V/propidium iodide method (A-V/PI) is a common flow cytometric method for the multiparametric analysis of cells in apoptosis. However, A-V/PI does not permit fixation and/or permeabilization of cells making impossible evaluation of intracellular markers, restricting the analysis in a narrow time frame after staining and excluding the possibility to study pathogen-infected cells. We developed a method permitting fixation and permeabilization of stained cells: Fixed Apoptotic/Necrotic (FAN) cells test. FAN relies on the same principle of A-V/PI, but uses reagents that maintain their binding and fluorescence characteristics after fixation/permeabilization: a fluorochrome-labeled anti-phosphatidylserine antibody and fluorescent amine-binding dyes. FAN was tested to discriminate apoptotic and necrotic cells using different stimuli on several cell types and results were always comparable to those obtained using A-V/PI. FAN, unlike A-V/PI, permitted to correlate cell death with intracellular and surface markers expression and to perform cytometry even two weeks after sample preparation. As fixation of stained cells inactivates infective pathogens, we used FAN in an in vitro model of Mycobacterium tuberculosis (Mtb) infection of macrophages to monitor cellular infection and cell death induction. Using a red-fluorescent Mtb, fluorochrome labeled anti-TNF- and anti-MHC class II monoclonal antibodies, FAN permitted to establish that the extent of macrophage death correlates with intracellular Mtb content and that dying cells accumulate TNF- and down-modulate MHC class II molecules. Results suggest that FAN may represent an additional tool to study programmed cell death particularly useful when fixation procedures are required for a safe infected sample analysis or to comparatively analyze multiple samples. (c) 2017 International Society for Advancement of Cytometr

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Alcune esperienze di valorizzazione del patrimonio ambientale e paesaggistico

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    Lo studio dei territori colpiti dagli eventi sismici ha messo in evidenza alcune esigenze strutturali che, se affrontate e trasformate in progettualità facendo leva sulle potenzialità del patrimonio ambientale e paesaggistico locale, potrebbero creare le condizioni per la rinascita socio-economica del Centro Italia

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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