351 research outputs found
Gene Stratton Porter
In 1886, author, naturalist and photographer, Geneva Grace Stratton, married Charles D. Porter, a druggist and banker from Geneva. She wrote several popular novels including Freckles, A Girl of the Limberlost, Laddie, and A Daughter of the Land
Gene Stratton Porter's Home at Wildflower Woods near Rome City, Indiana
Rome City was established in 1839. Gene Stratton-Porter, an author, naturalist and photographer, moved there and resided at the Cabin in Wildflower Woods on Sylvan Lake from 1914 until she moved to California in 1920. It is now a state historic site.The image is misidentified on the postcard, it is not Limberlost but Gene Stratton Porter's cabin in the Wildflower Woods near Rome City in Noble County.Noble County Journe
Outta my way piece on the author\u27s portrayal of the Maine towns of Stratton an
Outta my way piece on the author\u27s portrayal of the Maine towns of Stratton and Eustis in an article she wrote and published in Down East magazine\u27s February issue. The article received a critical review in The Original Irregular, a weekly paper that serves the communities of the western mountains of Maine
Stratton Island in Saco Bay is home to a cormorant colony, a much-maligned bird.
Stratton Island in Saco Bay is home to a cormorant colony, a much-maligned bird. The National Audubon Society assigns wardens to live on Stratton from late spring through the fall to monitor these and other migrant species. Double-crested Cormorant populations are declining in Maine, though the state still holds the largest nesting population on the U.S. East Coast. With details on the birds, which the author sketched and photographed
IFLA Journal. October 2021 [Special Issue: indigenous librarianship]
The IFLA Journal special issue on Indigenous Librarianship strives to position libraries and librarianship through an indigenous worldview and ways of knowing. Each article takes is own perspective on the topic, exploring issues such as colonization, reconciliation, representation and imagery, digital access, and resource management. The issue is the result of collaboration with IFLA Journal and the Indigenous Matters Section of IFLA. Led by guest editors Stephen Stratton and Camille Callison, this issue was supported by a committee that include Rashidah Bolhassan, Mohit Garg, Raj K. Bhardwaj, Martha Attridge Bufton, and Rebecca Bateman
IFLA Journal. October 2021 [Special Issue: indigenous librarianship]
The IFLA Journal special issue on Indigenous Librarianship strives to position libraries and librarianship through an indigenous worldview and ways of knowing. Each article takes is own perspective on the topic, exploring issues such as colonization, reconciliation, representation and imagery, digital access, and resource management. The issue is the result of collaboration with IFLA Journal and the Indigenous Matters Section of IFLA. Led by guest editors Stephen Stratton and Camille Callison, this issue was supported by a committee that include Rashidah Bolhassan, Mohit Garg, Raj K. Bhardwaj, Martha Attridge Bufton, and Rebecca Bateman
Preanalytical, analytical, and computational factors affect homeostasis model assessment estimates
OBJECTIVE: We investigated how beta-cell function and insulin sensitivity or resistance are affected by the type of blood sample collected or choice of insulin assay and homeostatis model assessment (HOMA) calculator (http://www.dtu.ox.ac.uk). RESEARCH DESIGN AND METHODS: Insulin was measured using 11 different assays in serum and 1 assay in heparinized plasma. Fasting subjects with normoglycemia (n = 12), pre-diabetes, i.e., impaired fasting glucose or impaired glucose tolerance (n = 18), or type 2 diabetes (n = 67) were recruited. Patients treated with insulin or those who were insulin antibody-positive were excluded. HOMA estimates were calculated using specific insulin (SI) or radioimmunoassay (RIA) calculators (version 2.2). RESULTS: All glucose values were within model (HOMA) limits but not all insulin results, as 4.3% were 300 pmol/l. beta-Cell function derived from different insulin assays ranged from 67 to 122% (median) for those with normoglycemia (P = 0.026), from 89 to 138% for those with pre-diabetes (P = 0.990), and from 50 to 81% for those with type 2 diabetes (P <0.0001). Furthermore, insulin resistance ranged from 0.8 to 2.0 (P = 0.0007), from 1.9 to 3.2 (P = 0.842), and from 1.5 to 2.9 (P <0.0001), respectively. This twofold variation in HOMA estimates from the various insulin assays studied in serum may be significant metabolically. Insulin was 15% lower in heparinized plasma (used in the original HOMA study) compared with serum, which is now more commonly used. beta-Cell function differed by 11% and insulin resistance by 15% when estimates derived from specific insulin were calculated using the RIA rather than the SI calculator. CONCLUSIONS: To enable comparison of HOMA estimates among individuals and different research studies, preanalytical factors and calculator selection should be standardized with insulin assays traceable to an insulin reference method procedure
Review of \u3ci\u3ePioneer Women: Voices from the Kansas Frontier\u3c/i\u3e By Joanna L. Stratton
The history of this book is as remarkable as the lives of the women it chronicles. While rummaging through her grandmother\u27s attic, Joanna L. Stratton discovered in yellowing folders the personal memoirs of eight hundred Kansas pioneer women, some describing events that had occurred as early as 1854. Lilla Day Monroe, Stratton\u27s great-grandmother, who was also the first woman to practice law before the Kansas Supreme Court, collected these narratives in the 1920s, asking women to write about their daily lives and experiences as early settlers. Monroe planned to publish their accounts in an anthology as a tribute to the pioneer housewives who helped to settle Kansas, their contributions having been largely ignored by historians.
With Monroe\u27s death in 1929, Lenore Monroe Stratton (Monroe\u27s daughter and the author\u27s grandmother) took over the project. But it eventually bogged down, and the memoirs were flled away in an attic cabinet, where Joanna L. Stratton discovered them in 1975. Six decades after its inception, the author has completed the project in superb fashion.
Stratton\u27s book is a social history of early Kansas settlement, based almost entirely on the eight hundred memoirs. It provides an intimate look into the daily activities of average settlers, focusing on the women\u27s side of pioneer life. Using excerpts from the narratives, the author ably documents the endurance, perseverance, hardiness, and optimism of Kansas pioneer women. It took these qualities to survive, as a woman\u27s life on the frontier was one of daily toil and frequent loneliness. The book tells of one young woman whose loneliness was so intense that, when left alone for the day, she would go out and lie down among the sheep for company.
Loneliness was only one of many hardships experienced by Kansas women. The book vividly describes their struggles with sickness, droughts, floods, grasshopper infestations, wolves, prairie fires, and blizzards. But men and women ex erie need these hardships together and, Stratton points out, they worked as partners to assure the survival of the family. Men and women alike delighted in social encounters; travelers were always welcome; and holidays and picnics broke the monotony of unending toil. Separate chapters are devoted to frontier schools, churches, towns, and war, with a concluding chapter on temperance and suffrage crusaders
Development of a cost-effectiveness model for optimisation of the screening interval in diabetic retinopathy screening
BACKGROUND:
The English NHS Diabetic Eye Screening Programme was established in 2003. Eligible people are invited annually for digital retinal photography screening. Those found to have potentially sight-threatening diabetic retinopathy (STDR) are referred to surveillance clinics or to Hospital Eye Services.
OBJECTIVES:
To determine whether personalised screening intervals are cost-effective.
DESIGN:
Risk factors were identified in Gloucestershire, UK using survival modelling. A probabilistic decision hidden (unobserved) Markov model with a misgrading matrix was developed. This informed estimation of lifetime costs and quality-adjusted life-years (QALYs) in patients without STDR. Two personalised risk stratification models were employed: two screening episodes (SEs) (low, medium or high risk) or one SE with clinical information (low, medium-low, medium-high or high risk). The risk factor models were validated in other populations.
SETTING:
Gloucestershire, Nottinghamshire, South London and East Anglia (all UK).
PARTICIPANTS:
People with diabetes in Gloucestershire with risk stratification model validation using data from Nottinghamshire, South London and East Anglia.
MAIN OUTCOME MEASURES:
Personalised risk-based algorithm for screening interval; cost-effectiveness of different screening intervals.
RESULTS:
Data were obtained in Gloucestershire from 12,790 people with diabetes with known risk factors to derive the risk estimation models, from 15,877 people to inform the uptake of screening and from 17,043 people to inform the health-care resource-usage costs. Two stratification models were developed: one using only results from previous screening events and one using previous screening and some commonly available GP data. Both models were capable of differentiating groups at low and high risk of development of STDR. The rate of progression to STDR was 5 per 1000 person-years (PYs) in the lowest decile of risk and 75 per 1000 PYs in the highest decile. In the absence of personalised risk stratification, the most cost-effective screening interval was to screen all patients every 3 years, with a 46% probability of this being cost-effective at a £30,000 per QALY threshold. Using either risk stratification models, screening patients at low risk every 5 years was the most cost-effective option, with a probability of 99-100% at a £30,000 per QALY threshold. For the medium-risk groups screening every 3 years had a probability of 43-48% while screening high-risk groups every 2 years was cost-effective with a probability of 55-59%.
CONCLUSIONS:
The study found that annual screening of all patients for STDR was not cost-effective. Screening this entire cohort every 3 years was most likely to be cost-effective. When personalised intervals are applied, screening those in our low-risk groups every 5 years was found to be cost-effective. Screening high-risk groups every 2 years further improved the cost-effectiveness of the programme. There was considerable uncertainty in the estimated incremental costs and in the incremental QALYs, particularly with regard to implications of an increasing proportion of maculopathy cases receiving intravitreal injection rather than laser treatment. Future work should focus on improving the understanding of risk, validating in further populations and investigating quality issues in imaging and assessment including the potential for automated image grading
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