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D-dimer testing to assess the individual risk of venous thromboembolic recurrence in non-elderly patients of both genders: follow the rules!
Cuore e nuove tecniche di palestra: la selezione dei pazienti e i carichi di lavoro
Obiettivo principale dello studio è stato quello di quantificare una
serie di variabili metaboliche, cardiovascolari ed ergometriche nel
corso di una seduta standard della durata di 50 min di spinning bike,
eseguita da istruttori di entrambi i sessi (6 maschi, 6 femmine).
Sono stati valutati vari parametri cardiometabolici ed emodinamici
ed i valori medi rilevati nei partecipanti per i parametri di potenza,
frequenza cardiaca e consumo di ossigeno sono stati di
120 ± 4 W, 136 ± 13 b/min e 32.8 ± 5.4 ml/kg/min per gli istruttori,
e 73 ± 43 W, 143 ± 25 b/min e 30 ± 9.9 ml/kg/min per le
istruttrici. L’analisi delle prestazioni individuali ha evidenziato come
il carico di lavoro nel corso della prova variasse tra moderato/
pesante a molto/estremamente pesante, essendo queste due
ultime condizioni decisamente prevalenti. I risultati ottenuti dimostrano
come questo tipo di attività di fitness abbia un impatto
molto elevato sulla funzione cardiovascolare e ne sconsigliano pertanto
la pratica a soggetti con storia di sedentarietà, specie se
avanti negli anni o decisamente anziani o con un elevato rischio
cardiovascolare.The main objective of this study was to evaluate a number of metabolic and cardiovascular variables during
a standard 50 min class performed by spinning bike instructors of both sexes: 6 males and 6 females. Mean
power output, heart rate, and oxygen uptake during the performance were 120 ± 4 W, 136 ± 13 bpm, and
32.8 ± 5.4 ml/kg/min respectively for males, and 73 ± 43 W, 143 ± 25 bpm, and 30 ± 9.9 ml/kg/min respectively
for females. The analysis of individual performances showed that these were compatible with a physical
exercise that ranged from moderate to heavy, to very heavy, the latter condition definitely prevailing. Results
show that this type of fitness activity has a high impact on cardiovascular function, and suggest that it
is unsuitable for unfit or sedentary individuals, especially if middle aged or elderly, who are willing to begin a
recreational physical activity program
Ischemic preconditioning of the muscle improves maximal exercise performance but not maximal oxygen uptake in humans
Is maximal exercise improvement induced by ischemic preconditioning maneuvers (IPM) related to plasma concentration changes of oxidative stress markers?
Effect of acute exercise on low molecular weight thiols in plasma
An important defence against free radicals is represented by plasma low molecular weight (LMW) thiols that compose a dynamic system of reduced and oxidized forms able to act as a buffer redox system. This study examined the effect of an acute graded exercise bout on LMW thiols in 16 young subjects (six sedentaries and 10 athletes). Blood analysis was performed before and immediately after the exercise and total and reduced thiols were measured in order to evaluate the thiol redox status. Findings suggested that the exercise test proposed was not enough to imbalance the redox status of all LMW thiols. However, when the redox status was evaluated for each thiol, it was evident that homocysteine (Hcy) redox status was significantly different after physical activity. In particular, we found a lower level of reduced Hcy after the exercise test both in sedentaries and in athletes. We concluded that duration and intensity of the proposed exercise were not enough to promote a reactive oxygen species production able to imbalance the redox thiols status and that the lowering of the reduced Hcy form may be due to the effect produced during the effort on the synthesis and/or removal processes of Hcy
Ischemic preconditioning of the muscle improves maximal exercise performance but not maximal oxygen uptake in humans
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