2,551 research outputs found
A historical comment about the GVT in short interval
No full textIn this article, the author introduces the history, progress and method in the Goldbach-Vinogradov Theorem in short interval by which every sufficiently large odd integer could be expressed as the sum of three almost equal prime numbers.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183488400018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701MathematicsCPCI-S(ISTP)
CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity
No full textRUVBL1
and RUVBL2 are ATPases associated with diverse cellular
activities (AAAs) that form a complex involved in a variety of cellular
processes, including chromatin remodeling and regulation of gene expression.
RUVBLs have a strong link to oncogenesis, where overexpression is
correlated with tumor growth and poor prognosis in several cancer
types. CB-6644, an allosteric small-molecule inhibitor of the ATPase
activity of the RUVBL1/2 complex, interacts specifically with RUVBL1/2
in cancer cells, leading to cell death. Importantly, drug-acquired-resistant
cell clones have amino acid mutations in either RUVBL1 or RUVBL2,
suggesting that cell killing is an on-target consequence of RUVBL1/2
engagement. In xenograft models of acute myeloid leukemia and multiple
myeloma, CB-6644 significantly reduced tumor growth without obvious
toxicity. This work demonstrates the therapeutic potential of targeting
RUVBLs in the treatment of cancer and establishes a chemical entity
for probing the many facets of RUVBL biology
Investigation on the DC CB Performance during a Current Interruption Failure at First Current Zero
No full textThe vacuum interrupter is used as the key component of an active DCCB due to its excellent interruption and dielectric recovery characteristics after current zero. The vacuum interrupter can only interrupt the fault currents below the limitation of a critical di/dt and TIV, otherwise it causes a reignition and the interruption failure. In this paper, a detailed active injection DC CB model is developed, considering operation delay of switches, parasitic parameters of switches and thorough control logic. The limitation dielectric strength between the vacuum gap is defined by the cold break down voltage. Based on the numerical modelling, investigation will be performed to see the performance of DC CB with a failure interruption on the first current zero. The simulation results can help to optimize the injection circuit parameters when DC CB has a failure on the first current zero and has to interrupt in the next current zeros. This algorithm will consider predefined threshold of di/dt, chopping current and variable operation time in different scenarios.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Intelligent Electrical Power Grid
Om de dødes (eller i det mindste åndens) nærvær før, under og efter Jesu død ifølge Johannesevangeliet: Replik til Jesper Tang Nielsen
No full textReplik til Jesper Tang Nielse
Technical performance of different DC CB technologies for future HVDC Grids
No full textMultiterminal dc (MTDC) network is preferred due to its reliability, security of supply and flexibility. However, MTDC network also comes with the protection challenges resulting from dc faults. Hence, the dc circuit breaker (DC CB) is imperative in such a network. In these recent years, several DC CB technologies have been proposed and demonstrated by different manufacturers. Besides, these DC CB technologies differ from each other in terms of the speed of operation, interruption capability and costs. Hence, for the optimal performance of the MTDC network, a study of the co-ordinative operation of different DC CB technologies is required. In this thesis, two typical types of DC CBs are modelled in detail and implemented in a 4-terminal MTDC network in PSCAD environment, by considering operation time, interruption capability and interruption characteristics. The obtained results are used for DC CB’s selection optimization methodology for the future MTDC networks. Similarly, a scaled model of DC CB has to be analysed in terms of its interruption capability in MTDC network considering various scenarios. Therefore, in this master thesis, technical performance of DC CB technologies is conducted for a test and multiterminal dc network in EMT based software environment.The DC CB is the key to unlock the reliable operation of a Multi-terminal direct current network, whereas fast, effective and accurate models are frequently needed for system-level studies. Due to higher subsystem components in DC CB, a detailed DC CB model creates a bottleneck in the network analysis. This thesis also proposes and compares, an average model with a detailed model of Voltage source converter Assisted Resonant Current (VARC) and Mechanical DC CB in MTDC Network in terms of their performance and computation time for two typical simulation cases. The average and detailed model is modelled and simulated on the PSCAD/EMTDC electromagnetic transient platform. Decisively, this thesis concludes by presenting an accurate response of the average model during the fast transient event, showing additional computational advantage.<br/
23.5 A Sub-1V 810nW Capacitively-Biased BJT-Based Temperature Sensor with an Inaccuracy of ±0.15°C (3σ) from -55°C to 125°C
No full textBJT-based temperature sensors are widely used because they can achieve excellent accuracy after 1-point calibration. However, they typically dissipate mu textWs of power and require supply voltages above 1V [1]. Although sensors based on DTMOSTs [2], [3], capacitively biased (CB) diodes and BJTs [4,5] have demonstrated sub-1V operation, this comes at the expense of accuracy. This paper presents a sub-1V CB BJT-based temperature sensor that achieves a 1-point-trimmed inaccuracy of 0.15°C (3σ) from -55 circC to 125 circC, which is 4times better than the CB BJT state-of-the-art [4]. It also achieves a resolution FoM of 0.34pJ.K2, which is 6.8 times better than that of state-of-the-art BJT-based sensors with a similar accuracy [1], [6], (Fig. 23.5.6).Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
The characteristics of the polish CB-language
No full textThe paper analyzes the language used by drivers on the Citizens’ Band radio (CB radio). The
users of the radio communicate only in speech, their communication is highly pragmatic and
based on partnership. The utterances alternate between formal and informal ones, which
determines the range and register of vocabulary. Drivers often use diminutives and polite
addresses thus creating the atmosphere of mutual respect and cordiality, which can be
comforting and reassuring for strangers who happen to establish a casual contact. The specific
language used on the CB radio fulfils two basic functions: it creates a sense of community
among drivers and protects the information passed on as warnings. At the end of the paper,
the author appends a comprehensive glossary of the CB language
Modelling of GO/PPy/CB and rGO/PPy/CB nanocomposite supercapacitors using an electrical equivalent circuit
No full textIn this study, supercapacitor device performances of graphene oxide (GO), reduced graphene oxide (rGO), polypyrrole (PPy), and ternary nanocomposites of GO, PPy, and carbon black (CB) as GO/PPy/CB and rGO/PPy/CB were firstly prepared using the in situ polymerization method. The obtained composite materials were characterized by scanning electron microscopy energy–dispersive X-ray (SEM–EDX), Fourier-transform infrared-attenuated transmission reflectance (FTIR-ATR), X-ray diffraction (XRD), thermal gravimetric analysis (TGA), atomic force microscopy (AFM), Brunauer–Emmett–Teller (BET) surface area analysis, cyclic voltammetry (CV), galvanostatic charge–discharge (GCD), and electrochemical impedance spectroscopic (EIS) methods. The highest specific capacitance (Csp) of the rGO/PPy/CB nanocomposite was obtained as Csp = 39, 48, and 27.86 F × g?1 by three methods of CV, GCD, and EIS, respectively. Two equivalent circuit models of Rs(CdlRct) and LRs(QRct) were presented to compare equivalent circuit parameters. Theoretical and experimental values are compatible with each other. Graphical abstract: [Figure not available: see fulltext.]. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Trakya ÜniversitesiThis work is a part of the research project NKUBAP.01.?NAP.19.213 approved by the Scientific and Research Project Unit (Tekirdag Namik Kemal University). This research grant is gratefully acknowledged. We thank Prof. Dr. Murat Turkyilmaz and Ozan Yoruk (PhD student) for TGA and BET measurements (TUTAGEM, Trakya University, Turkey)
„Misiek z okularami na hulajnodze”, czyli o CB-polszczyźnie
No full textThe paper analyzes the language used by drivers on the Citizens’ Band radio (CB radio). The users of the radio communicate only in speech, their communication is highly pragmatic and based on partnership. The utterances alternate between formal and informal ones, which determines the range and register of vocabulary. Drivers often use diminutives and polite addresses thus creating the atmosphere of mutual respect and cordiality, which can be comforting and reassuring for strangers who happen to establish a casual contact. The specific language used on the CB radio fulfils two basic functions: it creates a sense of community among drivers and protects the information passed on as warnings. At the end of the paper, the author appends a comprehensive glossary of the CB language
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