4,111 research outputs found

    [[alternative]]Lian...dou/ye Construction

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    [[abstract]]The thesis deals with the ‘lian…dou/ye …’ construction in modern Chinese. In order to clarify the informational status of ‘lian…’, issues on topic and focus are shown in the first part of this thesis. Then, discussions on semantic functions and conversational implicatures of this construction constitute the sencond part. Lastly, the formal complexity and pedagogical instructions will be presented as well.

    The Anticancer Properties and Apoptosis-inducing Mechanisms of Cinnamaldehyde and the Herbal Prescription Huang-Lian-Jie-Du-Tang (黃連解毒湯 Huáng Lián Jiě Dú Tang) in Human Hepatoma Cells

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    ABSTRACTHepatocellular carcinoma (HCC) has long been one of the most important causes of cancer mortality in the world. Many natural products and traditional herbal medicines have been used to treat HCC in Asian countries such as Japan, Korea, Taiwan, and China. The present review aims to describe the anticancer properties and apoptotic mechanisms of cinnamaldehyde, the bioactive ingredient isolated from cinnamon trees, and the herbal prescription Huang-Lian-Jie-Du-Tang (黃連解毒湯 Huáng Lián Jiě Dú Tang; HLJDT) against human hepatoma cells in vitro and in vivo. Implication of their treatment for the development of targeted therapy against HCC is discussed

    Antidiabetic Micro-/Nanoaggregates from Ge-Gen-Qin-Lian-Tang Decoction Increase Absorption of Baicalin and Cellular Antioxidant Activity In Vitro

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    The antidiabetic effects of Ge-Gen-Qin-Lian-Tang decoction (GQD) have been proven clinically. In a pharmacological study conducted on STZ-induced diabetic rats, the constitutive aggregates/sediments of Ge-Gen-Qin-Lian-Tang decoction exhibited stronger hypoglycemic and antioxidant activities compared to the soluble compositions. This study aims to demonstrate the pharmacological properties of aggregates derived from GQD by measuring permeability of the active monomer phytochemicals (e.g., baicalin) in a Caco-2 cell monolayer and determine the cellular viability, intracellular redox status (MDA and SOD), and insulin secretion of pancreatic β-cell line, INS-1, following STZ-induced oxidative stress. The aggregates were separated into three fractions, namely, “MA (microaggregates),” “400 g supernatant,” and “MNA (micro-/nanoaggregates),” by centrifugation at 400 ×g and 15000 ×g, respectively. Aggregates in the sediment increased baicalin absorption, showed little toxicity to β-cells, elevated intracellular SOD levels, and significantly suppressed oxidative damage effects on cellular viability and functions. The “MA” fraction had a larger particle size and provided higher antioxidant cellular protection than “MNA” in vitro, implying that the sediments may be the active components in the herbal decoction. The actions of these micro-/nanoaggregates may provide a new perspective for understanding the antidiabetic effects of herbal decoctions and aid in interpretation of synergistic actions between the multiple components

    sj-docx-1-jaf-10.1177_0148558X231185628 – Supplemental material for Relationship Institutions: Evidence From IPOs

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    Supplemental material, sj-docx-1-jaf-10.1177_0148558X231185628 for Relationship Institutions: Evidence From IPOs by Xudong Fu, Qin Lian, Tian Tang, Qiming Wang and Hua Christine Xin in Journal of Accounting, Auditing & Finance</p

    Phytochemical profiling and evaluation of the pharmacological effects of the Chinese herbal decoction Huang Lian Jie Du Tang

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    Die chinesische Dekoktmischung Huang Lian Jie Du Tang wird in der Traditionellen Chinesischen Medizin als Dekokt zur Vertreibung von Hitze und Toxitität verwendet. In der westlichen Medizin wird sie bei entzündlichen Magen-Darm Erkrankungen, Ekzemen und Hauterkrankungen sowie psychischen Erkrankungen verwendet. Die Dekoktmischung besteht aus unterschiedlichen Anteilen der folgenden Einzeldrogen: Radix Scutellariae, Fructus Gardeniae, Rhizoma Coptidis und Cortex Phellodendri.Im Rahmen der vorgelegten Dissertation wurden das phytochemische Profil der Dekoktmischung, sowie deren pharmakologische Effekte in Bezug auf Entzündungshemmung, untersucht. Dekokte der Einzeldrogen und der Kräutermischung wurden erstellt und mittels Flüssig-Flüssig Chromatographie mit n-Heptan, Dichlormethan, Ethylacetat und n-Butanol extrahiert. Die so gewonnenen Extrakte, sowie die verbleibenden wässrigen Rückstände wurden mittels Dünnschichtchromatographie, HPLC-DAD und LC-MS analysiert. Die anschließende Datenauswertung sowie eine Cluster Analyse führten zur Charakterisierung des phytochemischen Profils der Kräutermischung Huang Lian Jie Du Tang. Die gewonnenen Ergebnisse tragen in Zukunft wesentlich zu Qualitätssicherung des Kräuterdekoktes bei.Die, bei der Flüssig-Flüssig Extraktion, gewonnenen Extrakte und wässrigen Rückstände wurden zusätzlich auf ihre entzündungshemmenden Wirkungen gegen COX-1, COX-2, LTB4 Bildung und NO Produktion untersucht. Die entzündungshemmende Aktivität der Kräutermischung durch Inhaltsstoffe, wie z.B. Baicalein, aus den Einzeldrogen konnte bestätigt werden. Untersuchung der Extrakte mittels XTT Test in CCRF-CEM leukämischen Zellen sowie MRC-5 Lungenfibroblasten zeigte dass die untersuchten Proben nur sehr geringen Einfluss auf Zellviabilität und Proliferation haben und deshalb keine anti-Krebs Wirkung aufweisen.The Chinese herbal decoction Huang Lian Jie Du Tang is used in Traditional Chinese Medicine to clear away heat and relieve toxicity. In western medicine it is used to treat inflammatory diseases of the gastro intestinal tract, skin diseases and psychic disorders. The decoction mixture consists of varying portions of the four single herbs Radix Scutellariae, Fructus Gardeniae, Rhizoma Coptidis and Cortex Phellodendri.During this PhD Thesis, the phytochemical profile of the decoction mixture, as well as its pharmacological effects concerning anti-inflammatory activities were examined. Decoctions of the single herb components as well as of the mixture were prepared and extracted via liquid-liquid extraction with n-heptane, dichloromethane, ethyl acetate and n-butanol. The so gained extracts and the respective water residues were analysed using thin layer chromatography, HPLC-DAD and LC-MS. Interpretation and cluster analysis of the gained data led to the characterisation of the phytochemical profile of Huang Lian Jie Du Tang. The results will further on contribute to quality control of the decoction mixture.The extracts, which were gained via liquid-liquid extraction, as well as the respective water residues were also evaluated concerning their anti-inflammatory activity against COX-1 and COX-2 enzyme activity, LTB4 formation and NO production in vitro. Anti-inflammatory activity of the decoction mixture, caused by constituents such as baicalein, derived from the single drugs, could be confirmed. Additionally, the extracts were analysed using an XTT assay in CCRF-CEM leukaemia cells and MRC-5 lung fibroblasts. Analysis showed that the investigated samples only slightly influenced cell viability and proliferation and therefore, do not posses anti-cancer or cytotoxic activities in these cell lines. Additionally the findings of the XTT assays state that the anti-inflammatory activities could not be due to cytotoxicity.vorgelegt von Ute WidowitzAbweichender Titel laut Übersetzung der Verfasserin/des VerfassersGraz, Univ., Diss., 2012Zsfassung in dt. und engl. Sprach

    Traffic Monitoring and Vehicle Tracking using Roadside Camera

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    2006 IEEE International Conference on Systems, Man, and Cybernetics, Taipei, Taiwan, Oct.8-11This paper studies the integration and implementation of digital image processing techniques on the roadside camera for traffic monitoring and vehicle tracking. The image processing framework developed in this study is mainly composed of five stages: (1) pre-processing, (2) foreground segmentation, (3) shadow removal, (4) tracking, and (5) traffic parameters extraction. During the pre-processing stage, the information of road geometry is obtained and the camera is calibrated. At the foreground segmentation stage and shadow removal stage, moving vehicles are segmented from the original input images. To make the system more robust, an alpha-beta filter is used at the multi-vehicle tracking stage. Subsequently, related traffic parameters are extracted at the end of each tracking mechanism. The experimental results show that this system is capable of successfully extracting the traffic parameters, including the trajectory of the moving vehicles based on the image sequences captured by a digital camera on a free flow traffic in the daytime

    Virtual exhibition as a portal to authentic art experiences: exploring the immersive reproduction of exhibition in practice

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    Exhibitions are traditionally constrained by fixed times and locations, limiting access for a wider audience. Immersive reproduction, leveraging 3D reconstruction and virtual reality technologies, offers a way to transcend these temporal and spatial limitations. While previous research has largely focused on integrating mixed-reality elements within physical museum spaces, treating VR as a supplementary tool, our research positions VR as the primary “portal” to authentic artistic experiences. This demo showcases the complete process of immersive reproduction for Following the Fish, an exhibition featured at the 18th Venice International Architecture Biennale in 2023, offering valuable insights and references for future digital archiving and immersive reproduction of exhibitions

    sj-pdf-1-ijd-10.1177_10567895241247324 - Supplemental material for Investigation of pore structure evolution and damage characteristics of high temperature rocks subjected to liquid nitrogen cooling shock

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    Supplemental material, sj-pdf-1-ijd-10.1177_10567895241247324 for Investigation of pore structure evolution and damage characteristics of high temperature rocks subjected to liquid nitrogen cooling shock by Can Du, Jing Bi, Yu Zhao, Chaolin Wang, Wei Tang and Shuailong Lian in International Journal of Damage Mechanics</p

    sj-pdf-2-ijd-10.1177_10567895241247324 - Supplemental material for Investigation of pore structure evolution and damage characteristics of high temperature rocks subjected to liquid nitrogen cooling shock

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    Supplemental material, sj-pdf-2-ijd-10.1177_10567895241247324 for Investigation of pore structure evolution and damage characteristics of high temperature rocks subjected to liquid nitrogen cooling shock by Can Du, Jing Bi, Yu Zhao, Chaolin Wang, Wei Tang and Shuailong Lian in International Journal of Damage Mechanics</p
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