1,721,217 research outputs found

    Annual Khu Yek Chung and Tan Chun Tee memorial awards

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    The College of Computer Studies (CCS) held the Annual Khu Yek Chung and Tan Chun Tee Memorial Awards ceremonies for CCS Most Outstanding Teacher and Student. Rhodora Reyes, Software Technology Department faculty was chosen as Most Outstanding Teacher and Hubert Gapuz, Information Technology major as Most Outstanding Student. William Khu was guest of honor

    [Suplico named Khu Yek Chiong and Tan Chun Tee Memorial Endowment Fund most outstanding CBE faculty]

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    Marketing Management faculty Luz Suplico was named Khu Yek Chiong and Tan Chun Tee Memorial Endowment Fund Most Outstanding College of Business and Economics (CBE) faculty during the CBE Week recognition ceremonies. She was also honored by the College of Education (CED) as one of the Outstanding faculty during the CED\u27s celebration of Catholic Teachers Day on January 26

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    In vitro anti-cancer properties of bisindole alkaloids from Tabernaemontana corymbosa and Alstonia penangiana against human colon cancer cells / Tan Chun Hoe

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    The natural product is a continuing source for the discovery of potential anti-cancer drugs. Two iboga-vobasine bisindole alkaloids, namely 16'-decarbomethoxyvoacamine (1) and its 19,20-dihydro derivative, 16'-decarbomethoxydihydrovoacamine (2) were previously isolated from the stem-bark extract of Tabernaemontana corymbosa. In addition, a macroline-akuammiline bisindole angustilongine A (3) and a linearly-fused macroline-sarpagine bisindole, angustilongine M (4) were isolated from the leaf and stem-bark extract of Alstonia penangiana, respectively. The preliminary cytotoxicity screening demonstrated that bisindoles 1–4 exhibited strong growth inhibitory effects against a wide array of human cancer cell lines, predominantly against colorectal cancer (CRC). Herein, the antiproliferative activity and underlying mechanisms of the bisindoles in human colorectal adenocarcinoma HT-29 and carcinoma HCT 116 were further investigated. The studies demonstrated that 1–4 exhibited pronounced antiproliferative activities against HT-29 and HCT 116 cells in both dose- and time-dependent manners without significant cytotoxicity to normal human colon fibroblast (CCD-18Co). Owing to its highest antiproliferative activity and selectivity in both CRC cell lines, 2 was chosen for the subsequent studies. Brief treatment with 2 for 24 h potently inhibited the colonies formation of the CRC cells and the effect was suggested to be long-term and irreversible. Bisindole 2 inhibited the formation of HT-29 spheroids (tumor-like cell aggregates) in 3D experiments in a dose-dependent manner. In HT-29, the binding of 2 at the Taxol- binding site of β-tubulin contributed to the generation of ROS, causing DNA damage. Consequently, three signaling pathways, i.e., JNK/p38, p21Cip1/Rb/E2F, and p21Cip1/Chk1 were activated. In contrast, treatment with 2 enhanced the drug metabolism in HCT 116 through the induction of cytochrome P450 enzymes, subsequently leading to the oxidative damage to DNA and activation of the GADD45/p21Cip1 pathway. In both CRC cell lines, the activation of their respective pathways resulted in cell cycle arrest, induction of caspase-dependent mitochondrial apoptosis, and inhibition of metastasis (in HCT 116 only). In addition, treatment with 2 has reversed the 5-fluorouracil (5-FU) resistance of HCT 116-5FUR (5-fluorouracil-resistant HCT 116 derivative cell line) in a synergic manner with 5-FU. Lastly, the calculated physiochemical properties of 2 suggested that it could be a suitable candidate to be used as an in vivo model due to its high bioavailability, non-toxicity, and good drug-likeness score

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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