101,461 research outputs found
Integrating Supports for Ubiquitous Eldercare
No full textThe demographic compression, along with heightened life expectancy and decreases in fertility rates, is dramatically raising the number of older adults in society, thus putting many countries’ healthcare systems under significant pressure. Eventual loss of physical and cognitive skills makes it quite difficult for elders to maintain autonomous life-styles and often forces them to move to assisted living environments, with severe emotional and social impacts. The main challenge for the years to come is, therefore, to identify more sustainable approaches to eldercare, capable of improving elders’ independence in order to avoid, or at least to delay, hospitalization. Providing suitable support for elders is, indeed, a highly challenging problem. However, recent advancements in pervasive computing enable the development of advanced eldercare services. The main focus of eldercare research to date has been directed towards the development of smart environments capable of assisting elders, for example, in monitoring their psychophysical conditions, and of reminding and facilitating their routine activities. Few research efforts have been directed towards the investigation of solutions capable of improving social engagement for elders living alone, and of facilitating the coordination of care-giving efforts. The chapter provides an overview of the state-of-the-art technology in eldercare research and suggests the extension of available solutions by adopting integrated approaches that aim at addressing both assistance and social/coordination issues stemming from eldercare
M2M-Based Metropolitan Platform for IMS-Enabled Road Traffic Management in IoT
No full textMachine-to-machine communications are gaining tremendous interest from mobile network operators, equipment vendors, device manufacturers, as well as research and standardization bodies. Indeed, M2M is a promising technology for the development of Internet of Things communications platforms, with high potential to enable a wide range of applications in different domains. However, providing suitable answers to the issues stemming from IoT platform design requires middleware-level solutions to enable seamless interoperability between M2M-based applications and existing Internetbased services. To the best of our knowledge, available proposals in the field are still immature and tend to be proof of concept prototypes that address specific issues stemming from IoT domains. This article starts from a different perspective and aims at investigating the possibility of implementing M2M solutions on top of currently available, mature, production-level solutions. In this vein, we here present and discuss the design and implementation of an M2M application in the field of road traffic management that integrates, for the sake of efficiency, with a broad IMS-based service infrastructure
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Theory of financial risk
Get PDFThis paper examines relationships between theory of financial risk and size. Based on the work of Makridakis / Taleb [2009] and Taleb / Tapiero [2009], presents the problems of excessive risk and imbalances caused by the size of firms. Markets mixed on firm growth traps externalities can influence risk, high-cost for the commons. A policy of regulation and control in markets, while necessary, are still insufficient in economies with little institutional support. Externalities of risk and firm size categories are fundamental to understanding the present financial crisis since the economies of scale.Finance, financial engineering, risk assesment.
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
Get PDFIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
Get PDFIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
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