99 research outputs found
Interplay between European regulation and national policies in biodiversity conflict reconciliation
No full textSuccessful public conservation policies at various governmental levels have increased some populations of protected species to the extent that they are causing damage to human activities. As a reaction public authorities are developing biodiversity reconciliation policies. Finland and Germany have both created reconciliation policies including a package of measures like management of population, support of technical measures and compensation for damage. All these measures are affected by European policy and law, though no special reconciliation policy has been adopted at European level. This article explores the options European legislation offers and the restrictions it imposes on member states. Based on experiences with German and Finnish biodiversity reconciliation policies, the interrelationship between European and national regulation is elaborated, leading to suggestions for better coordination of reconciliation policies between different governmental levels. --Biodiversity conflict reconciliation,European regulation,fisheries and aquaculture,local damage management,nature conservation,policy instruments
Internationalisation of The Carpentries: Lessons learnt on the way
No full text
At the end of 2018, there was growing interest in the internationalisation of the Carpentries
teaching material for non-English language speaking countries. As part of this community-
driven initiative, I became involved in the translation of the Software Carpentry materials
into Japanese. In this lightning talk, I would like to share my experience on organising,
managing, and collaborating with people living in Japan, using Git and GitHub.
ABOUT THE AUTHOR
I have been involved with The Carpentries since I began my MSc at the University of Otago;
first as a learner, then a helper, and finally as an instructor. I became an official Carpentries
instructor in 2018, and since then, I have been involved in the translation of The Carpentries
material into Japanese.
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Stitches: Blending landscape fabric through the golden threads of spatial identity in San Riku coastline, Otsuchi, Iwate, Japan
No full textDisaster prevention and coastal protection of Otsuchi have affected the livelihood and the daily pattern of lifestyle of the regular Otsuchian. This work represents the alternative to a typical top down prefectural level demand for a line based infrastructural solution to disaster prevention and creates the required importance of livelihood, culture and identity of a place over the protection structure. While in the design of such critical areas it is important to place protection of the citizens at a high level, it is also a necessity to understand the situation of each city as different from each other. In this way, the genius loci of a place is founded. Along the San Riku coastline where the tsunami and earthquake hit the hardest due to the landscape features and the proximity to the epicenter the government has set a list of top down governed structures that have impacted the urban fabric of the city, This document looks at one of these towns “Otsuchi” and how alternate solutions based on the historical and landscape features of the district can help create landscapes of livelihood for the citizens. Otsuchi among many other Japanese cities faces the issue of a shrinking population due to a lack of economy, a lack of education in the rural areas and a lack of opportunities. The design document also looks at how Identity crisis in a Rias coastline/ Aditya Athreya Rao/ TU Delft 1 landscape can create a set of cyclical opportunities for the people to develop their town responsibly and sustain-ably as they see fit. Landscape design seeks to provide opportunity to the stakeholders to further create, it provides the platform for this creation and the thesis looks at ideas and solutions on ways this can be done. Keywords: Landscape Infrastructure, Identity, Contextual Design Genius Loci, Landscape Design, New landscapesFlowscapesArchitecture, Urbanism and Building Sciences | Landscape Architectur
Body Mass Index and Pathway Dysregulation in Cancer
No full textObesity has been a major global problem for more than a decade, associated with many noncommunicable diseases such as cancer. The number of obese people, both adults and children, has risen in every country of the world and the trend will likely to continue. Cancers are caused by dysregulation of various molecular pathways that allow tumour cells to proliferate, survive and migrate. One of the difficulties associated with the treatment of cancers is the identification of the underlying biological pathways that drive tumorigenesis. This research aims to determine whether gene expression signatures exist that are specific to obesity across multiple cancer types, and to investigate whether there are any common pathways being dysregulated in cancers based on these genetic signatures. In this work no genetic signatures differentially expressed genes were found between obese and non-obese patients that were common across multiple cancer types. However, the Akt, epidermal growth factor receptor (EGFR) , transforming growth factor-B (TGFB) and Src pathways may have a role in promoting the tumour progression in patients that are obese. It is likely that there is some complex mechanism underlying the relationship between obesity and cancer. A better understanding of the pathways being dysregulated in cancer cells in obese patients may lead to improved clinical decisions, and contribute towards personalised treatment in the future
Body Mass Index and Pathway Dysregulation in Cancer
No full textObesity has been a major global problem for more than a decade, associated with many noncommunicable diseases such as cancer. The number of obese people, both adults and children, has risen in every country of the world and the trend will likely to continue. Cancers are caused by dysregulation of various molecular pathways that allow tumour cells to proliferate, survive and migrate. One of the difficulties associated with the treatment of cancers is the identification of the underlying biological pathways that drive tumorigenesis. This research aims to determine whether gene expression signatures exist that are specific to obesity across multiple cancer types, and to investigate whether there are any common pathways being dysregulated in cancers based on these genetic signatures. In this work no genetic signatures differentially expressed genes were found between obese and non-obese patients that were common across multiple cancer types. However, the Akt, epidermal growth factor receptor (EGFR) , transforming growth factor-B (TGFB) and Src pathways may have a role in promoting the tumour progression in patients that are obese. It is likely that there is some complex mechanism underlying the relationship between obesity and cancer. A better understanding of the pathways being dysregulated in cancer cells in obese patients may lead to improved clinical decisions, and contribute towards personalised treatment in the future
Transmission-order optimization for bidirectional device-to-device (D2D) communications underlaying cellular TDD networks—A graph theoretic approach
No full textUykan, Zekeriya (Dogus Author) -- Jantti, Riku (Dogus Author)Device-to-device (D2D) communications underlaying cellular networks is a promising concept that has several advantages over the traditional cellular networks. In the TDD system, the frame structure defines the order of uplink and downlink transmission slots. Typically, a TDD system is synchronized, and the same transmission order (TO) is used in all cells. In a direct D2D link, we have the freedom of selecting the TO of the devices freely. To our best knowledge, no paper has explicitly examined the TO optimization problem in D2D communications underlaying cellular network so far. In this paper, we focus exactly on this problem: once the proper co-channel D2D pairs are determined in the network, how do we minimize the network interference by optimally determining the TOs in all D2D links (together with co-channel cellular links) in the network, which is an NP-complete problem. In this paper, we formulate the TO optimization problem from a graph theoretic point of view: 1) we show that the TO optimization problem is equal to a constraint balanced min-cut graph partitioning problem of our defined augmented graph; and 2) we propose and analyze a distributed and a centralized efficient asynchronous clustering algorithm for solving the TO optimization probleme quivalently for themin-cut of our proposed augmented graph. Computer simulations for the TDD-based D2D underlaying cellular network show that the proposed distributed and centralized algorithms, called ABCAMiC and CABCAMiC, respectively, 1) remarkably outperform the reference case where all TOs are fixed, 2) converge within a relatively small number of steps and generally converge in only a few epochs even for a large number of cellular and D2D users, and 3) the expected performance of the (partly/fully) distributed ABCAMiC is almost equal to that of the centralized solution CABCAMiC, which generally gives near-global optimal solution to the TO optimization problem
Udmurt spatial cases dataset
No full text<p>This is a dataset and accompanying R code for studying the variation between the two source cases (elative and egressive) and goal cases (illative and terminative). The data folder include four files including data for analysing the effect of properties of the Landmark and the associated verb form on the choice between the source and goal cases. The script folder contains four R markdown files, which contain the code to analyse the four data files.</p>
<p>The data set is manually annotated for various variables that are hypotethised to affect the choice between the pairs of cases. Not all the variables are used in the analysis presented. </p>
<p>In V2.0 the R code is heavily changed. Only the code in files R_goal3 and R_source3 should be used in analysis. The data files are the same in both versions, but in V2.0 they have been checked and some minor mistakes have been fixed. Therefore, only the data files in the new version should be used if replicationg the analysis represented by the code in files R_goal3 and R_source3.</p>
<p>The author of this dataset is Riku Erkkilä and it is published under CC-BY-NC-ND licence. If used in a publication, please refer to this publication as well as mention the original source:</p>
<p>Arkhangelskiy, Timofey 2018: <em>Udmurt corpus</em>. http://udmurt.web-corpora.net/index.html.</p>
<p>The R packages used in the analysis are:<br>Hothorn, Torsten; Hornik, Kurt; Strobl, Carolin & Zeileis, Achim 2023: <em>Party 1.3-13</em>. https://CRAN.R-project.org/package=party.<br>Wickham, Hadley 2023: <em>Tidyverse 2.0.0</em>. https://CRAN.R-project.org/package=tidyverse.</p>
LocusZoom-like Plots for GWAS Results
No full textPublic release of the LocusZoom-like package.
This package allows the user to create regional Manhattan plots from p-values, log(p-values), or log(Bayes Factors) with points coloured according to LD and genes annotated beneath. The LD input can be generated from the users own data (e.g. for a non-reference population). The package comes with a number of reference files for gene annotation, but is not limited to the use of these files.
This package was created for use with human SNP data, but can be used to plot non-human data.Supplement to https://github.com/Geeketics/LocusZooms/tree/v2.
Classification and Management of Game Bugs
No full textThe objective of this Bachero’s thesis was to improve testing and increase the understanding of the responsibilities of testers in different phases of a software implementation process. This thesis has information on the impact that quality assurance has in game development.
Motivation to create this thesis comes from the author’s own work experience in testing games. Data is compared to personal experience as the author had started working as quality assurance 2 years ago. The author designed a Jira workflow on a kanban board with suggestions that in theory should work well.
This thesis was written using academic sources which were from printed and online literature. The results of this thesis show the importance of testing when high quality is the goal, combined with a well structured bug management framework.
Aiming for high quality is one of the greatest goals of game development. Although not every company supports the belief that quality assurance and bug testers are a necessity for their games, the findings of this research show otherwise. The cost of bugs and loss of reputation can not be ignored in the evolving tech world.
The conclusion of this thesis is that testing is very important for the quality of the product which also reduces the amount of money needed to be spent on maintenance. The thesis also indicates how early testing not only helps find more bugs, but they are easier to fix in the beginning as such, they save the company money. This thesis shows how well communication and clear bug reporting enhance the number of defects found and fixed
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