147,061 research outputs found

    Comparison of electrical activity of lateral and medial stabilizers of the patella and further diagnostically relevant risk factors in athletes with and without patellofemoral pain and in a Tai Chi group

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    Khoshraftar Yazdi N. Comparison of electrical activity of lateral and medial stabilizers of the patella and further diagnostically relevant risk factors in athletes with and without patellofemoral pain and in a Tai Chi group. Bielefeld (Germany): Bielefeld University; 2010.Patellofemoral pain syndrome (PFPS) is a term for a variety of pathologies or anatomical abnormalities leading to a type of anterior knee pain and is the most common single diagnosis among runners and in sport medicine centers. Despite this high incidence, the exact cause of these disorders remains enigmatic. The major complain of patients with PFPS is retropatellar pain during activities such as running, squatting, going up and down stairs, prolonged sitting, cycling, and jumping. Some of risk factors in athletes with PFPS were considered and compared with athletes without PFPS in the present study. In addition, since Tai Chi (TC) helps or reduces the load on the lower limbs joints, particularly in knee, a TC group was chosen to compare with the two other groups

    BIOMECHANICAL VALIDATION OF TRANSFER ASSESSMENT INSTRUMENT (TAI) IN EVALUATING DIFFERENT INDEPENDENT TRANSFERS IN WHEELCHAIR USERS

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    Transfers are one of the most essential and physically demanding daily activities for wheelchair users (WUs). The Transfer Assessment Instrument (TAI) is the first tool to standardize the way clinicians evaluate transfer techniques and to help identify specific skills to target during transfer training. The study was to validate the function of the TAI, indicate the effects of transfer skills in performing toilet transfers in two different setups, and evaluate the immediate effects of individualized TAI-based structured transfer training. Up to twenty-six WUs performed transfers to a level-height bench and a toilet with a side and front setup while force plates, load cells, and a motion capture system recorded the biomechanics of their natural transferring skills. Their skills were simultaneously evaluated by two clinicians using the TAI. Logistic and multiple linear regression models were used to determine the relationships between TAI scores and the joint kinetic variables on both arms. Multivariate analysis of variance models were built to test biomechanical differences between using and non-using skill groups during toilet transfers with a side and front setup respectively. Wilcoxon signed-rank test was used to compare the differences of the biomechanical variables between pre and post TAI-based transfer training. The results showed that the completion of TAI skills was associated with lower resultant moments and/or their rates of rise at both shoulders and/or elbows (p<0.02). Some skills increased the moment magnitude or rate on the leading side (p<0.03). Compared to WUs who did not use skills, WUs who scooted forward in their wheelchair and used an appropriate handgrip and head-hip techniques had better shoulder positioning and lower joint forces and moments on both arms in toilet transfers with a side setup (p<0.04), and WUs who used close wheelchair positioning had significantly lower trailing arm loading (p=0.03) in a front setup. The TAI-based transfer training intervention improved the leading shoulder posture (p<0.04) and reduced the joint forces and moments and their rates on both shoulders and trailing elbow and wrist (p<0.05). Structured training and the routine practice of TAI skills is recommended to help reduce the risk of developing secondary injuries

    Economic analysis of Tai Chi as a means of preventing falls and falls related injuries among older adults, CHERE Working Paper 2006/4

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    This study has examined the costs and consequences of a randomised controlled trial of a community based Tai Chi program for people over 60 years of age. The hypothesis for the trial was that compared to non-participants, participants in the Tai Chi program would have fewer falls and may experience additional health and other benefits. In terms of resource use it was anticipated that the Tai Chi program would use additional resources in terms of running costs but was expected to save resources as a result of falls prevented. Data for this economic evaluation were collected prospectively alongside the randomised controlled trial. The aim of this evaluation was to investigate the cost-effectiveness of Tai Chi as means of preventing falls in elderly people living in the community. Costs included were those of the Tai Chi trial and health service utilisation (including GP and specialist and other consultations, tests, hospitalisations and medications). Effectiveness was measured as the number of participants in the intervention and control groups, all participants and the number of falls avoided. SPSS was used to analyse the data; Fisher?s exact and the student?s t-test were used to test differences between the intervention and control groups. From the perspective of NSW Health, the cost of providing Tai Chi as part of this trial (81232)outweighedanycostsofhealthserviceprovision(81232) outweighed any costs of health service provision (24795). Only a small proportion used health services and this mostly involved the use of over-the-counter pain relieving medication and GP consultations. Only 3 people were admitted to hospital. There were no significant differences between the study and control groups in terms of utilisation and costs except in terms of overall costs where the control group costs were significantly more than the study group (p=0.43). However, this difference was driven by the cost of one admission to hospital. In the trial 3/216 falls resulted in hospitalisation. This means that for every 100 falls avoided, 1.4 serious falls were prevented. Assuming that Tai Chi would continue to prevent falls at the same rate as the trial, 740 individuals would need to participate in Tai Chi to avoid 100 falls and 1.4 serious falls. The value of avoiding a small number of serious falls must be weighed against the high cost of treating and managing the consequences of such falls.Tai chi, economic aspects, Australia

    sj-docx-1-tai-10.1177_20499361231179668 – Supplemental material for Predictors of adverse safety events and unscheduled care among an outpatient parenteral antimicrobial therapy (OPAT) patient cohort

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    Supplemental material, sj-docx-1-tai-10.1177_20499361231179668 for Predictors of adverse safety events and unscheduled care among an outpatient parenteral antimicrobial therapy (OPAT) patient cohort by Kaylyn N. Billmeyer, Jennifer K. Ross, Elizabeth B. Hirsch, Michael D. Evans, Susan E. Kline and Alison L. Galdys in Therapeutic Advances in Infectious Disease</p

    sj-docx-2-tai-10.1177_20499361231179668 – Supplemental material for Predictors of adverse safety events and unscheduled care among an outpatient parenteral antimicrobial therapy (OPAT) patient cohort

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    Supplemental material, sj-docx-2-tai-10.1177_20499361231179668 for Predictors of adverse safety events and unscheduled care among an outpatient parenteral antimicrobial therapy (OPAT) patient cohort by Kaylyn N. Billmeyer, Jennifer K. Ross, Elizabeth B. Hirsch, Michael D. Evans, Susan E. Kline and Alison L. Galdys in Therapeutic Advances in Infectious Disease</p

    Synthesis of 2-substituted 9-oxa-guanines {5-aminooxazolo[5,4-d]pyrimidin-7(6H)-ones} and 9-oxa-2-thio-xanthines {5-mercaptooxazolo[5,4-d]pyrimidin-7(6H)-ones}

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    Oxazolo[5,4-d]pyrimidines can be considered as 9-oxa-purine analogs of naturally occurring nucleic acid bases. Interest in this ring system has increased due to recent reports of biologically active derivatives. In particular, 5-aminooxazolo[5,4-d]pyrimidine-7(6H)-ones (9-oxa-guanines) have been shown to inhibit ricin. The preparation of a series of 2-substituted 5-aminooxazolo[5,4-d]pyrimidin-7(6H)-ones and related 5-thio-oxazolo[5,4-d]pyrimidines is described, including analogs suitable for further elaboration employing “click” chemistry utilizing copper-catalyzed Huisgen 1,3-dipolar cycloadditions. Two of the compounds prepared were found to inhibit ricin with IC50 ca. 1–3 mM

    sj-doc-1-tai-10.1177_20499361241245822 – Supplemental material for Fixing a Hole: a retrospective cohort study evaluating HAV, HBV, tetanus screening, and vaccination during hospitalization in persons who use substances

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    Supplemental material, sj-doc-1-tai-10.1177_20499361241245822 for Fixing a Hole: a retrospective cohort study evaluating HAV, HBV, tetanus screening, and vaccination during hospitalization in persons who use substances by Amber C. Streifel, Jose Eduardo Rivera Sarti, Monica K. Sikka, Michael Conte, Bradie Winders and Cara D. Varley in Therapeutic Advances in Infectious Disease</p

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Tai-txi per organitzar el cervell

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    Aging Neuroscience acaba de publicar un treball d"un equip de recerca de l"Acadèmia de Ciències Xineses i de la Universitat de Pequín encapçalat per Xi-Nian Zuo, director del laboratori de connectòmica funcionalla connectòmica és la disciplina científica que estudia com s"estableixen i es mantenen les connexions neurals dins el cervell, que suggereix que la pràctica del tai-txi optimitza l"organització funcional del cervell dels adults

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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