117,349 research outputs found
Il bilancio idrico consortile come strumento per un utilizzo sostenibile della risorsa idrica
No full textViene presentato un esempio di bilancio idrico consortile valutando gli ingressi idrici in un sistema di bonifica del parmigiano e le diverse destinazioni idriche all'interno del comprensorio tra perdite dai canali,perdite di sitema,distribuzioni irrigue.
Si è potuto constatre come l'efficienza globale del sistema sia collettivo che aziendale risulti modesta (30%) e quindi si è posta in evidenza la necessità di intervenire sia a livello aziendale che consortile
Determinazione del risparmio idrico attraverso il bilancio idrico consortile
No full textAttraverso il bilancio idrico di un comprensorio di bonifica vengono evidenziate le ripartizioni della risorsa idrica tra le varie perdite idriche e gli utilizzi aziendal
Chemical characterization of non-psychoactive Cannabis sativa L. extracts, in vitro antiproliferative activity and induction of apoptosis in chronic myelogenous leukaemia cancer cells
No full textIn this study, extracts from non-psychoactive Cannabis sativa L. varieties were characterized by means of ultra high-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-HRMS) and their antiproliferative activity was assessed in vitro. The human chronic myelogenous leukaemia cell line K562 was chosen to investigate the mechanism of cell death. The effect on the cell cycle and cell death was analysed by flow cytometry. Proteins related to apoptosis were studied by western blotting. Mechanical properties of cells were assessed using the Micropipette Aspiration Technique (MAT). The results indicated that the cannabidiol (CBD)-rich extract inhibited cell proliferation of K562 cell line in a dose-dependent manner and induced apoptosis via caspase 3 and 7 activation. A significant decrease in the mitochondrial membrane potential was detected, together with the release of cytochrome c into the cytosol. The main apoptotic markers were not involved in the mechanism of cell death. The extract was also able to modify the mechanical properties of cells. Thus, this hemp extract and its pure component CBD deserve further investigation for a possible application against myeloproliferative diseases, also in association with other anticancer drugs
Signatures on the Y chromosome of the demographic history of Elba island (Northern Mediterranean)
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Y-STR haplotyping in French immigrants of Maghreb origin: drop of diversity and implications on the matching probability and the assignment of ethnic affiliation
No full textPopulation structure in Sardinia on the basis of quantitative palmar dermatoglyphic traits.
No full textProfilo genetico della popolazione corsa e toscana attraverso l’analisi di sistemi autosomici STR
No full textInactivation of Eimeria spp. oocysts in aqueous environment assisted by a gas-liquid dielectric barrier discharge
No full textAmong human and animal diseases agents, parasites are those that show, with very few exceptions, an environmental resistance far superior with respect other pathogens [1]. This is due to the complex structure of the wall of their infective stages, that makes them particularly resistant to almost all physical and chemical agents. In this work, a novel technique to inactivate coccidian parasites in liquid environment has been investigated and implemented. A Petri dish filled with 20 ml of water contaminated by Eimeria spp. oocysts has been placed within a plasma reactor constituted by a lower HV exposed electrode and an upper grounded copper strip electrode covered by a ceramic slab (Fig. 1). The reactor has been supplied with sinusoidal and nanosecond-pulsed voltage waveforms varying the application time. In both cases an atmospheric pressure Dielectric Barrier Discharge (DBD) has been ignited in the air gap above the liquid surface and in contact with it [2]. The temperature of the solution and its pH level were not significantly changed by plasma treatment. The concentration of ozone and hydrogen peroxide increase by increasing treatment time [2]. Plasma treatment efficacy has been detected considering a representative population of 100 oocysts. For both discharges, treatment efficacy has been found to be dose dependent (Fig. 2). After an energy dose treatment of about 100 kJ/l, the number of sporulated oocytes are roughly halved with respect the control sample. Results are statistically significant with a p<0.01 in the worst case.
[1] N.C. Smith, F.J. Lunden, H.D. Chapman, Parasitology Today, 14, 215-218 (1998).
[2] Neretti G, Taglioli M, Colonna G and Borghi C A, Plasma Sources Sci. Technol. 26, 015013 (2017)
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