1,720,982 research outputs found
"Si Può Fare!!" Ovvero: dai j/cm2 alla pratica
No full textL'uso del laser nella pratica clinica, applicazione nelle principali chirurgie e terapie dei pets
L'uso del laser a diodi nei piccoli mammiferi esotici
No full textL'uso del laser, sia chirurgico che terapeutico, sta trovando sempre maggior impiego e diffusione in medicina veterinaria. Purtroppo la maggior parte delle pubblicazioni è reperibile unicamente sulle riviste specializzate di medicina umana. Nel presente articolo vengono presentati alcuni spunti sull'utilizzo di un particolare tipo di laser, quello a diodi, strumento che trova molteplici applicazioni nel campo dei piccoli mammiferi esotic
Considerazioni pratiche sull'uso della dexmedetomidina nell'anestesia dei conigli (Oryctolagus cuniculus)
No full textLe visite dei nuovi animali d'affezione rappresentano una realtà sempre in aumento nella quotidiana pratica clinica. I continui progressi in campo farmacologico ed anestesiologico hanno permesso di avere a disposizione vari protocolli di sedazione sicuri e multimodali. Dal 2008 è disponibile sul mercato una nuova molecola: la dexmedetomidina, una sostanza che rientra nella categoria degli alfa2adrenergici. L'obiettivo di questo lavoro è quello di descrivere le esperienze maturate in un periodo di circa due anni nell'utilizzo della forma destrogira di questa molecola in associazione con ketamina e butorfanolo nell'anestesia dei conigli
Localization of the Serotonin Transporter in the Dog Intestine and Comparison to the Rat and Human Intestines
No full textSerotonin is crucial in gastrointestinal functions, including motility, sensitivity, secretion, and the inflammatory response. The serotonin transporter (SERT), responsible for serotonin reuptake and signaling termination, plays a prominent role in gastrointestinal physiology, representing a promising therapeutic target in digestive disorders. Serotonin transporter expression has been poorly investigated in veterinary medicine, under both healthy and pathological conditions, including canine chronic enteropathy, in which the serotonin metabolism seems to be altered. The aim of the present study was to determine the distribution of SERT immunoreactivity (SERT-IR) in the dog intestine and to compare the findings with those obtained in the rat and human intestines. Serotonin transporter-IR was observed in canine enterocytes, enteric neurons, lamina propria cells and the tunica muscularis. Data obtained in dogs were consistent with those obtained in rats and humans. Since the majority of the serotonin produced by the body is synthesized in the gastrointestinal tract, SERT-expressing cells may exert a role in the mechanism of serotonin reuptake
The comparison of latero-medial versus dorso-palmar/plantar drilling for cartilage removal in the proximal interphalangeal joint
No full textAnatomical organization of the lateral cervical nucleus in Artiodactyls
No full textThe presence of the lateral cervical nucleus (LCN) in different mammals, including humans, has been established in a number of anatomical research works. The LCN receives its afferent inputs from the spinocervical tract, and conveys this somatosensory information to the various brain areas, especially the thalamus. In the present study, the organization of the calf and pig LCN was examined through the use of thionine staining and immunohistochemical methods combined with morphometrical analyses. Specifically, the localization of calbindin-D28k (CB-D28k) and neuronal nitric oxide synthase (nNOS) in the LCN was investigated using the immunoperoxidase method. Calf and pig LCN appear as a clearly defined column of gray matter located in the three cranial segments of the cervical spinal cord. Thionine staining shows that polygonal neurons represent the main cell type in both species. The calf and pig LCN contained CB-D28k-immunoreactive (IR) neurons of varying sizes. Large neurons are probably involved in the generation of the cervicothalamic pathway. Small CB-D28k-IR neurons, on the other hand, could act as local interneurons. The immunoreactivity for nNOS was found to be mainly located in thin neuronal processes that could represent the terminal axonal portion of nNOS-IR found in laminae III e IV. This evidence suggests that nitric oxide (NO) could modulate the synaptic activity of the glutamatergic spinocervical tracts. These findings suggest that the LCN of Artiodactyls might play an important role in the transmission of somatosensory information from the spinal cord to the higher centers of the brain
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Localisation of Cannabinoid and Cannabinoid-Related Receptors in the Horse Ileum
No full textColic is a common digestive disorder in horses and one of the most urgent problems in equine medicine. A growing body of literature has indicated that the activation of cannabinoid receptors could exert beneficial effects on gastrointestinal inflammation and visceral hypersensitivity. The localisation of cannabinoid and cannabinoid-related receptors in the intestine of the horse has not yet been investigated. The purpose of this study was to immunohistochemically localise the cellular distribution of canonical and putative cannabinoid receptors in the ileum of healthy horses. Distal ileum specimens were collected from six horses at the slaughterhouse. The tissues were fixed and processed to obtain cryosections which were used to investigate the immunoreactivity of canonical cannabinoid receptors 1 (CB1R) and 2 (CB2R), and three putative cannabinoid-related receptors: nuclear peroxisome proliferator-activated receptor-alpha (PPARcz), transient receptor potential ankyrin 1 and serotonin 5-HT1 a receptor (5-HT1aR). Cannabinoid and cannabinoid-related receptors showed a wide distribution in the ileum of the horse. The epithelial cells showed immunoreactivity for CB1R, CB2R and 5-HT1aR. Lamina propria inflammatory cells showed immunoreactivity for CB2R and 5-HT1IaR. The enteric neurons showed immunoreactivity for CB1R, transient receptor potential ankyrin 1 and PPAR alpha. The enteric glial cells showed immunoreactivity for CB1R and PPAR alpha. The smooth muscle cells of the tunica muscularis and the blood vessels showed immunoreactivity for PPAR alpha. The present study represents a histological basis which could support additional studies regarding the distribution of cannabinoid receptors during gastrointestinal inflammatory diseases as well as studies assessing the effects of non-psychotic cannabis-derived molecules in horses for the management of intestinal diseases. (C) 2021 Elsevier Inc. All rights reserved
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