1,721,009 research outputs found
Intrusion Detection for Secure Clustering and Routing in Mobile Multi-hop Wireless Networks
No full textIntrusion detection and secure routing schemes have been proposed for increasing security and reliability in critical wireless scenarios. In this paper we present an integrated secure routing system based on Intrusion Detection Systems (IDS) and Statistically Unique and Cryptographically Verifiable (SUCV) identifiers. The proposed IDS has been used for the support of secure Ad Hoc On Demand Distance Vector (AODV) routing, named IDS-based Secure AODV (IS-AODV), in wireless ad hoc and vehicular network scenarios. Our IDS is based on the detection of behavior anomalies on behalf of neighbor hosts, with passive reactions, aiming to create a cluster whose route paths will include only safe nodes, eventually. Simulation results show that the proposed IDS is effective in isolating misbehaving hosts, and it assists the AODV secure routing scheme to converge in finding safe end-to-end routes
Use of pyridoxine-alpha-ketoglutarate (PAK) in hepatic encephalopathy
No full textPyridoxine-alpha-ketoglutarate (PAK) was administered to patients with high blood ammonia levels and with clinical signs of hepatic encephalopathy (HE). Plasma concentrations of ammonia decreased and clinical symptomatology improved. The activity of PAK was greater than that of lactulose in lowering blood ammonia levels but not significantly different in its relief of neuropsychic symptoms
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Anaerobic co-digestion of a lignocellulosic residue with different organic wastes: Relationship between biomethane yield, soluble organic matter and process stability
No full textThe aim of this paper was to deepen the knowledge of anaerobic co-digestion of lignocellulosic residues and evaluate the role of soluble organic matter during co-digestion. Buckwheat milling residue (buckwheat hull) was co-digested with different organic wastes to evaluate the effect of co-digestion on biomethane yield, process stability, and their relationship with soluble organic matter. Results showed that co-digestion increased the biomethane yields of buckwheat hull and the best result was achieved from the co-digestion with slaughterhouse wastes (+254% of cumulative biomethane production). Kinetic analysis showed that fruit wastes and brewery trub affected positively anaerobic digestion of lignocellulosic residues, enhancing biomethane potential (+84% and +166%, respectively) and reducing lag phase duration. A positive correlation was found between the soluble organic matter and the biomethane yields during co-digestion experiments. Nevertheless, co-digestion with fruit wastes was affected by an excessive acidification in the early stage of AD (pH 5.7) caused by the rapid conversion of sugars into volatile fatty acids (7 g L-1 at day 15). Although all the digestates showed high concentrations of plant nutrients (the average content of total N was 7.8% dry weight), they were also characterized by residual phytotoxicity (germination index was always 0.0%). results. Increasing the amount of easy biodegradable organic matter during lignocellulosic residues treatment should be the main goal when selecting co-digestion substrates. Chemical composition of co-digestion substrates should be carefully considered, with particular regard to soluble organic matter, to ensure the optimal development of anaerobic digestion with lignocellulosic residues
The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy
Full text linkG protein-coupled receptors (GPCRs) are vital cell surface receptors that govern a myriad of physiological functions. Despite their crucial role in regulating antitumor immunity and tumorigenesis, therapeutic applications targeting GPCRs in oncology are currently limited. This review offers a focused examination of selected protumorigenic chemokine and metabolite-sensing GPCRs. Specifically, the review highlights five GPCRs able to orchestrate tumor immunobiology at three main levels: tumor immunity, cancer cell expansion, and blood vessel development. The review culminates by illuminating emerging therapies and discussing innovative strategies to harness the full potential of GPCR-targeted treatments, by applying a multireceptor and patient-specific logic
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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