1,720,958 research outputs found
Lo sbrigliamento delle ulcere cutanee
No full textThe aim of this study is to review different methods of debridement in chronic wounds and to identify the evidence of debriding agents in wound healing. Debridement is an essential part of the tissue repair process and is defined as the removal of devitalized tissue from the wound bed. The accumulation of this tissue is regarded to prevent or delay granulation and epithelialization. Debridement techniques are divided into mechanical and non-mechanical methods on the basis of the physical peculiarities of the means employed and into selective and non-selective methods regarding the preservation or not of vital tissue from the wound bed. Advantages and disadvantages of each procedure are taken in to account to select the best form of debridement for each type of chronic wound. Surgical debridement is the most aggressive form and the more rapid compared to other techniques. It is essential to prevent infection and to remove dry thick eschars mainly in pressure ulcers. Autolytic debridement is the most easy and well tolerated from the patient and it is obtained through the use of occlusive dressings. Other forms of debridement such as the larva-therapy were used in the past and today have been reconsidered as useful and safe methods. The enzymatic and wet to dry debridements are the most common methods in our country and this is mainly due to the availability of these products. Chronic wounds are often contaminated with devitalized tissue and foreign material, which represent a barrier to cells migration and a source of infection. Selection of the debridement technique must consider the patient compliance, the wound size, the amount of exudate and the skill of the operator
Valutazione clinica e strumentale dell'attività terapeutica di un vasoprotettore contenente vitamina PP,vitamina C ed estratti fitoterapici titolati in escina,bromelina,antocianosidi nella cura delle ulcere
No full textBackground. Chronic leg ulcers due to venous insufficiency represent a significant burden for the national sanitary system. Although the role of venous hypertension as a key pathogenetic factor of this lesion is clear, several microcirculatory mechanisms involved in the tissue repair process remain to be clarified. The purpose of this study was to evaluate the efficacy and tolerability of a vasoactive drug for the treatment of varicose leg ulcers.
Methods. The study was a prospective randomized trial lasting eight weeks. Twenty patients matched for sex, age, wound dimensions and with clinical and instrumental evidence of chronic venous insufficiency were enrolled in this study. Patients attended a weekly consultation at the outpatients clinic for chronic leg ulcers of the Department of Dermatology at the University of Pisa and they were randomized into two groups according to treatment: G1 (n=10) vasoactive drug, occlusive dressing, elastic bandage, G2 (n=10) occlusive dressing, elastic bandage. During the study, subjective parameters were evaluated: intensity of pain, paresthesia, heaviness and objective parameters: intensity of oedema, wound area, transcutaneous tissue gas monitoring (O2 - CO2).
Results. At the end of the study a marked reduction of subjective symptoms such as pain and paresthesia was observed with an increase of oxygen tissue perfusion in the G1 group compared to the G2 group. No significant differences were observed in the two groups about the remaining parameters investigated.
Conclusions. The drug investigated in this study showed a good tolerability and efficacy in weakening the clinical symptoms related to venous insufficiency. The positive effect of the vasoactive drug on transcutaneous oxygen tension confirms a direct action on the microcirculatory system, which could positively modulate the tissue repair process
Pattern VEP alterations in psoriatic patients may indicate a sub clinic optic neuritis
No full textWe examined 44 subject (Group A) of both sexes (27 males and 17 females) aging between 16 and 80 (average: 45 +/- 16.6), divided into age bands, affected by mild-medium psoriasis with PASI (psoriasis area and severity index) between 1.2 and 48.6 (average: 11.2 +/- 9.7) without any other disease and we performed pattern transient VEP (Visual Evoked Potential) at the frequencies usually Used in clinical experience (73', 36' 18' check size). For a good statistic comparison we choose 55 healthy subjects (group B) divided into a L,,e hands oil which we performed the same test. Comparison of VEP parameters between psoriatic and healthy subjects. showed in group A 10 normal (22.7%) and 34 pathological (77.3%). In the latter group there are 16 subjects who show only a P100 reduced amplitude (36.3%), 3 with only increased latency (6.8%), 15 with alterations of both values (34%). The achieved data show that more than 3/4 of group A subjects have VEP alterations as index of the presence of a sub clinic optic neuritis With a probably toxic autoimmune origin due to the action of TNF alpha, of IgG, of ECP or of other cytokines (IL6, IL7, etc) that are increased in the blood of this patients. The electro physiologic monitoring of optic nerve seems to represent a good routine test to evaluate the global conditions of psoriatic patients
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Vale do Turio e Serradela: estratégias para o seu planeamento, ordenamento e gestão paisagística
Full text linkDissertação de Mestrado em Arquitetura PaisagistaNo planeamento, ordenamento e gestão paisagística as definições de paisagem e unidades de paisagem são cruciais para a caraterização e análise de uma dada área, neste caso do concelho de Vieira do Minho, com estudo específico no vale do Turio e Serradela.
É fundamental que se proceda não só à caraterização e análise do local, como também à compreensão do caráter da paisagem, levando assim a uma avaliação de possíveis propostas a desenvolver para o local, sendo necessário, então seguir uma determinada metodologia para se tirar um melhor partido do estudo do local, tendo esta como base os princípios gerais do PIER e do “Landscape character assessment”.
Seguindo esta metodologia, são propostas diversas estratégias, tendo como princípio a promoção do local, assegurando a conservação, preservação e valorização do património natural e histórico-cultural existente, criando-se assim diversas sinergias.In planning and landscape management landscape settings and scenic are essential for the characterization and analysis of a given area, in this case of Vieira do Minho, with specific study in the Turio valley and Serradela.
It is essential, not only the characterization and analysis of the site, but also the understanding of the landscape character, thus leading to an assessment of possible proposals management of the site following a given methodology, based on the general principles of “PIER” and landscape character assessment.
Following this methodology are proposed several strategies, based on the principle promoting local, ensuring the conservation, preservation and enhancement of natural and historical and cultural heritage, thus creating a diversity of synergies
Vale do Turio e Serradela: estratégias para o seu planeamento, ordenamento e gestão paisagística
No full textDissertação de Mestrado em Arquitetura PaisagistaNo planeamento, ordenamento e gestão paisagística as definições de paisagem e unidades de paisagem são cruciais para a caraterização e análise de uma dada área, neste caso do concelho de Vieira do Minho, com estudo específico no vale do Turio e Serradela.
É fundamental que se proceda não só à caraterização e análise do local, como também à compreensão do caráter da paisagem, levando assim a uma avaliação de possíveis propostas a desenvolver para o local, sendo necessário, então seguir uma determinada metodologia para se tirar um melhor partido do estudo do local, tendo esta como base os princípios gerais do PIER e do “Landscape character assessment”.
Seguindo esta metodologia, são propostas diversas estratégias, tendo como princípio a promoção do local, assegurando a conservação, preservação e valorização do património natural e histórico-cultural existente, criando-se assim diversas sinergias.In planning and landscape management landscape settings and scenic are essential for the characterization and analysis of a given area, in this case of Vieira do Minho, with specific study in the Turio valley and Serradela.
It is essential, not only the characterization and analysis of the site, but also the understanding of the landscape character, thus leading to an assessment of possible proposals management of the site following a given methodology, based on the general principles of “PIER” and landscape character assessment.
Following this methodology are proposed several strategies, based on the principle promoting local, ensuring the conservation, preservation and enhancement of natural and historical and cultural heritage, thus creating a diversity of synergies
- …
