1,720,972 research outputs found
Correspondence: Left ventricular pacing rate lower than expected during manual pacing threshold test in a biventricular defibrillator
No full textNo abstract availabl
Sedation with midazolam for electrical cardioversion
No full textBackground: Electrical cardioversion (ECV) usually requires the assistance of the anesthesiology team.
To avoid this dependence, previous studies have considered the use of sedation with benzodiazepines
administered by cardiologists. We describe our experience with intravenous Midazolam during cardioversion.
Methods:We performed 280 ECV in 202 patients sedated with intravenous Midazolam, without anesthesiology
supervision. In scheduled cardioversions, we tested two protocols of Midazolam administration:
a bolus of 3 mg, followed by 2 mg each minute until necessary, and a loading dose of 0.09–0.1 mg/kg.
In cardioversions performed during electrophysiology studies or defibrillator implant, Midazolam was
administered by small repeated doses during the entire procedure.
Results: Midazolam was effective to obtain adequate sedation in 99% of cases. All patients had amnesia
with regards of the cardioversion. A loading dose of Midazolam allowed a shortening of the procedural
time without serious adverse events. Intubation or the assistance of an Anesthetist was never necessary.
Conclusion: Sedation with Midazolam for ECV is effective and well tolerated, with some cautions discussed.
A loading dose of Midazolam is well tolerated and further reduces the procedural time
Atrial fibrillation and recurrent ventricular fibrillation during hypokalemia in Brugada syndrome
No full textAtrial Fibrillation and Recurrent Ventricular Fibrillation During Hypokalemia
in Brugada Syndrome. A 41-year-old man with Brugada syndrome (BS) and no previous
episodes of aborted sudden death or syncope referred to local emergency room for an episode of symptomatic
atrial fibrillation. Blood chemistry results showed hypokalemia (2.9 mEq/L). The other parameters
were within the normal range. After few minutes, an episode of ventricular fibrillation treated with biphasic
DC shock 150 J occurred. In successive 2 hours, the patient experienced recurrent episodes of ventricular
tachycardia and fibrillation. Each biphasic DC shock 150 J was effective to restore sinus rhythm. No further
episodes occurred after normalization of serum levels of potassium. Before discharge, an implantable
cardioverter defibrillator was inserted to prevent sudden cardiac death. Hypokalemia increases the risk
of arrhythmic events in BS. (PACE 2005; 28:1350–1353
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Implantable cardioverter defibrillators: from evidence of trials to clinical practice.
No full textA series of landmark randomized trials has validated the role of implantable cardioverter defibrillators (ICDs) not only in the setting of secondary prevention of sudden cardiac death (SCD) but also in the challenging subset of primary prevention of SCD, i.e. for high-risk patients without previous malignant ventricular tachyarrhythmias. Despite definite indications provided by consensus guidelines, the use of ICDs in clinical practice still encounters a series of barriers mainly related to the characteristics of such treatment (a 'rescue' treatment) and its up-front cost, resulting in substantial under-referral and rationing. Cost is likely to remain a major determinant of full acceptance, and implementation of ICD therapy and the problem of how broadened evidence-based indications for implantation can be translated into routine clinical practice require an analysis of available economic resources and identification of priorities for health care. Economic analysis (cost-effectiveness, cost-utility and cost-benefit estimates) provides the most appropriate tool for weighing ICD costs against likely eventual outcome benefits. A series of data indicate that the use of ICDs in appropriately selected high-risk SCD patients is associated with cost-effectiveness ratios similar to, or better than, other accepted treatments, such as renal dialysis. Improvement in risk stratification for SCD and assessment of the cost-effectiveness profile of ICD treatment in specific subgroups of patients appears to be a crucial step in any attempt to maximize health outcomes in a context of limited economic resources
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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