1,720,983 research outputs found

    Economi­a de la integracion regional.

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    ¿Cuáles son los motivos que han inducido a los Países Europeos a fundar la Comunidad Europea y, posteriormente, reforzar el acuerdo a través de la Unión Europea? ¿Qué motivaciones son las que llevan a otros Países a solicitar la adhesión a la UE, aceptando reglas y políticas ya establecidas por otros y aceptando, además, afrontar costos de ajustes particularmente elevados? ¿Qué es lo que empuja, fuera de la UE, a realizar intentos, como el Mercosur, para lograr acuerdos de integración regional dirigidos a la creación de un mercado interno liberalizado e integrado? Aún más, ¿cuál es la motivación de la existencia de períodos alternados de entusiasmo o de pesimismo en el proceso de construcción europea? ¿De qué modo la teoría económica puede dar una respuesta a estas preguntas? Este libro pretende brindar a los estudiantes universitarios y a los operadores económicos interesados, la posibilidad de profundizar los conocimientos teóricos –y las relativas aplicaciones concretas– sobre la integración económica regional. Los estudiantes adquirirán habilidades específicas sobre el uso de los principales modelos elaborados por la ciencia económica para explicar las motivaciones y las consecuencias de los acuerdos regionales: tales habilidades permitirán a ellos afrontar el análisis de situaciones reales, en particular, de los éxitos y los malogros del proceso de integración Europea, en las otras áreas de integración regional, y de las perspectivas futuras de profundización

    The rise in cytoplasmic ubiquitin levels is an early step in the response of parasympathetic ganglionic neurons to axonal injury followed by regeneration

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    We investigated the involvement of ubiquitin in the neuronal response to axonal injury in the quail parasympathetic ciliary ganglion by immune-light and electron microscopy. Image analysis of immunoreacted cryosections shows that ubiquitin-immunoreactivity in the ciliary neurons increases significantly 6 hours after postganglionic nerve crush. The immunolabeling reaches a peak 1 day after injury and begins to decrease between days 3 and 6 when, in contrast to the cytoplasm, numerous highly eccentric nuclei are strongly immunolabeled. Electron microscopy shows ubiquitin-immunoreactivity associated with cytoplasmic organelles and with several postsynaptic densities of the numerous synapses established by the preganglionic boutons on the soma of the ciliary neurons. The number of immunopositive postsynaptic densities increases significantly 1 day after axonal damage, followed by temporary detachment of the preganglionic boutons from the injured neurons between days 3 and 6. The early increase in cytoplasmic ubiquitin-immunoreactivity suggests a prompt ubiquitination of damaged proteins addressed to degradation, while the nuclear immunolabeling may reflect high histone ubiquitination, a process involved in keeping chromatin transcriptionally active. The possible ubiquitin-mediated removal of postsynaptic apparatus constituents such as ACh receptors, proteins involved in their clustering and stabilization, and/or adhesion molecules may be a crucial step for the detachment of the preganglionic boutons, thus favoring injury-induced synaptic plasticity

    Studio ed elaborazione di cifre indice per la progettazione degli impianti vinicoli

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    Numerose e continue sono le indagini nei vari settori industriali al fine di costruire indicatori e parametri capaci di sintetizzare e descrivere rapidamente e compiutamente un impianto industriale. Le cifre Indice, da anni, rappresentano un valido strumento per lo studio di fattibilità e per la gestione degli ampliamenti degli stabilimenti industriali. Numerose in letteratura sono le ricerche sviluppate in tal senso nell’ambito dei settori industriali più disparati che vanno da quello meccanico, a quello alimentare. I motivi di questa circostanza stanno nel fatto che le cifre indice costituiscono un utile ed efficace mezzo di analisi preventiva sia dei costi che delle risorse da impiegare in qualsiasi iniziativa produttiva. In questo contesto si inserisce il presente lavoro che vuole mettere in luce gli aspetti tecnologico-produttivi più rilevanti di una particolare industria italiana, quella del vino, molto importante dal punto di vista economico e strategico nel campo agro-alimentare. Negli ultimi venti anni, infatti, l’evoluzione di questo settore è stata notevole sia “in cantina” che “in campo”, soprattutto per soddisfare le mutate richieste sia di tipo qualitativo che quantitativo del mercato del vino. A tal scopo, si vogliono porre in rilievo i principali parametri impiantistici che sono alla base di una corretta progettazione (manodopera, superficie degli impianti, consumo d’acqua, elettricità e combustibili ecc.) e gestione degli impianti per la produzione del vino, cercando di individuare, se esiste, un legame di causa effetto tra la quantità di risorse da impiegare ed il livello produttivo degli impianti

    PREFERENZE COMMERCIALI E POLITICHE DI COOPERAZIONE CON I BALCANI

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    L’integrazione subregionale appare lo strumento fondamentale della trasformazione dell’area balcanica, sia per affrontare i problemi comuni, come quelli dell’ambiente, delle infrastrutture materiali, della riduzione dei costi di transazione per il movimento delle merci (le procedure doganali), sia, soprattutto, per trarre i maggiori vantaggi dalle opportunità offerte dagli accordi di integrazione nell’U

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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