1,720,966 research outputs found

    Assessment of nutritional status and risk of death in maintenance haemodialysis patients

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    Malnutrition is a major determinant of longterm outcome of maintenance haemodialysis (MHD) patients. The aim of this study was to evaluate the efficiency of electrical body impedance measurement (BIA) to indicate malnutrition and to predict clinical outcome of MHD patients. BIA was performed during a two year-time period in 126 MHD patients. Twenty-two patients died during this time period. Forty-six patients were re-examined at 2 years interval. The cross sectional analysis of the 126 MHD patients demonstrated a significant positive correlation between serum albumin (ALB) and phase angle (PA), reactance (Xc), body cell mass (BCM). Age and extra-cellular volume % of total body water (ECW%) correlated negatively with ALB. No correlation was found between body mass index (BMI), or sp Kt/V and ALB. The longitudinal study of 46 patients demonstrated no significant variation in ALB and sp Kt/V, a slight, but statistically significant reduction in BMI (p<0.05) and a highly significant reduction in PA, Xc, BCM, while ECW% significantly increased. Significantly lower values of PA, Xc and BCM and significantly higher values of ECW% were found in the 22 patients deceased within 2 years in comparison with still alive patients, while no difference was found for ALB and sp Kt/V values. BMI seems inadequate to assess nutritional status in MHD. Data derived from BIA (PA, Xc, BCM and ECW%) are significantly correlated with ALB, which is a validated marker of malnutrition in MHD patients. BIA seems even more sensitive than ALB to predict the risk of death in MHD patient

    Trail Meatmarket juvenile hockey team

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    L-R: Back Row: Steve Matovich, L. Tognotti, D. Michealy, B. Smart, A. Bonutto, H. McKay, B. Rae, A. Martin. Front Row: A. LeRose, B. Dimock, A. Tognotti, D. Twaddle, A. Balano, M. Turik

    Albumin modification and fragmentation in renal disease.

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    Albumin is the most important antioxidant substance in plasma and performs many physiological functions. Furthermore, albumin is the major carrier of endogenous molecules and exogenous ligands. This paper reviews the importance of post-translational modifications of albumin and fragments thereof in patients with renal disease. First, current views and controversies on renal handling of proteins, mainly albumin, will be discussed. Post-translational modifications, namely the fragmentation of albumin found with proteomic techniques in nephrotic patients, diabetics, and ESRD patients will be presented and discussed. It is reasonable to hypothesize that proteolytic fragmentation of serum albumin is due to a higher susceptibility to proteases, induced by oxidative stress. The clinical relevance of the fragmentation of albumin has not yet been established. These modifications could affect some physiological functions of albumin and have a patho-physiological role in uremic syndrome. Proteomic analysis of serum allows the identification of over-expressed proteins and can detect post-translational modifications of serum proteins, hitherto hidden, using standard laboratory techniques

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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