2,150 research outputs found

    The role of Plasmodium falciparum var genes in malaria in pregnancy

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    Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected erythrocytes binding to host receptors in the placenta such as chondroitin sulphate A (CSA). Identification of the parasite ligand(s) responsible for placental adhesion could lead to the development of a vaccine to induce antibodies to prevent placental sequestration. Such a vaccine would reduce the maternal anaemia and infant deaths that are associated with malaria in pregnancy. Current research indicates that the parasite ligands mediating placental adhesion may be members of the P. falciparum variant surface antigen family PfEMP1, encoded by var genes. Two relatively well-conserved subfamilies of var genes have been implicated in placental adhesion, however, their role remains controversial. This review examines the evidence for and against the involvement of var genes in placental adhesion, and considers whether the most appropriate vaccine candidates have yet been identified

    Introduction. Shakespeare: Overlapping Mediascapes in the Mind

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    Introduction to the issue 'Shakespeare in the Media. Old and New', Anglistica aion, 15.2, 2011, co-edited with co-author Katherine Rowe, discussing the place of Shakespeare in the media today and the 'state of the art' of Shakespeare studies on the topic

    Letter from Sanford Rowe and W. W. Bass to Carl Hayden

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    Letter from Sanford Rowe and W. W. Bass to Carl Hayden requesting a re-examination on the proposed park boundaries as they are disadvantageous to current land owners surrounding the canyon

    Plant cell walls

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    Introduction

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    Timothy Turley, Spring 1992 ROTC Awards Day

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    ROTC Spring Awards Day was held in Rowe Hall at Jacksonville State University. Shown Timothy Turley receives the Lt. Grady E. McBride Memorial Award from Lt. Col. William Stone.https://digitalcommons.jsu.edu/rotc_photos/3216/thumbnail.jp

    Fig. 3 in Cranial Anatomy of Citipati osmolskae (Theropoda, Oviraptorosauria), and a Reinterpretation of the Holotype of Oviraptor philoceratops

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    Fig. 3. Palatal view of the holotype cranium of Citipati osmolskae IGM 100/978. Abbreviations in appendix 1.Published as part of CLARK, JAMES M., NORELL, MARK A. & ROWE, TIMOTHY, 2002, Cranial Anatomy of Citipati osmolskae (Theropoda, Oviraptorosauria), and a Reinterpretation of the Holotype of Oviraptor philoceratops, pp. 1-24 in American Museum Novitates 3364 on page 7, DOI: 10.1206/0003-0082(2002)3642.0.CO;2, http://zenodo.org/record/473483

    Are NOWs being used as savings accounts?

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    Has the introduction of interest-bearing NOW accounts altered the nature of M1? That monetary aggregate, of course, is intended to measure purely transactions balances as typified by conventional checking accounts. But some observers think that consumers are using the NOW component of M1 as savings as well as transactions balances. If so, then M1 contains a nontransactions component; consequently, its growth rate compatible with any given rate of GNP growth is higher than before the introduction of NOWs. In this article, Timothy Q. Cook and Timothy D. Rowe marshal evidence on the use of NOW accounts to see if they are being employed as savings vehicles. They try to determine if consumers have consolidated their regular checking and savings accounts into NOWs. They also compare the characteristics of NOWs to those of other transactions and savings accounts. In general, they find no evidence of widespread use of NOWs as savings accounts. They conclude that there is no reason to believe that the introduction of interest-bearing checking accounts has altered the long-run relationship between M1 and economic activity.NOW accounts
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