1,721,048 research outputs found

    Essential veterinary education in avian medicine: a global perspective

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    Avian medicine is a relatively recent discipline in the veterinary curriculum, and is definitely not considered a topical issue. However, in the face of a growing demand for poultry meat worldwide, and in view of the health issues surrounding wild, exotic and pet birds, the relevance of avian medicine should be acknowledged and taken into account when revising curricula

    Vaccine Interaction and Protection against Virulent Avian Metapneumovirus (aMPV) Challenge after Combined Administration of Newcastle Disease and aMPV Live Vaccines to Day-Old Turkeys

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    Newcastle disease virus (NDV) and avian metapneumovirus (aMPV) are among the most impactful pathogens affecting the turkey industry. Since turkeys are routinely immunized against both diseases, the hatchery administration of the combined respective live vaccines would offer remarkable practical advantages. However, the compatibility of NDV and aMPV vaccines has not yet been experimentally demonstrated in this species. To address this issue, an aMPV subtype B live vaccine was administered to day-old poults either alone or in combination with one of two different ND vaccines. The birds were then challenged with a virulent aMPV subtype B strain, clinical signs were recorded and aMPV and NDV vaccine replication and humoral immune response were assessed. All results supported the absence of any interference hampering protection against aMPV, with no significant differences in terms of clinical scoring. In addition, the mean aMPV vaccine viral titers and antibody titers measured in the dual vaccinated groups were comparable or even higher than in the group vaccinated solely against aMPV. Lastly, based on the NDV viral and antibody titers, the combined aMPV and NDV vaccination does not seem to interfere with protection against NDV, although further studies involving an actual ND challenge will be necessary to fully demonstrate this hypothesis

    SVILUPPO E APPLICAZIONE DI TEST DIAGNOSTICI MOLECOLARI PER L’IDENTIFICAZIONE E LA CARATTERIZZAZIONE DEI VIRUS DELLA MALATTIA DI MAREK CIRCOLANTI IN ITALIA

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    Marek's disease (MD) is one of the most common lymphoproliferative diseases of chickens which causes mononuclear infiltration of different tissues and organs, such as peripheral nerves, gonad, viscera, muscle and skin. It is caused by an Alphaherpesvirus, called MDV or Gallid Herpesvirus 2 (GaHV-2). Although it has been studied in all its aspects from the early ‘60s and vaccines are now used all over the world, many issues remain unresolved due to the complexity of the disease. In order to activate specific surveys in the field, the IZSVe has developed a series of molecular diagnostic methods for the MD. The development of these tests makes a rapid and robust diagnosis possible, allowing to distinguish the vaccine strains from those pathogens and to identify the pathotype in a short time. Samples from backyard farms, samples (environmental dust, feathers, spleens and livers) taken from an industrial flock of breeders in the first months of life, as well as samples from clinical cases of particular interest were analysed for validation of the methods. The data obtained so far confirm the high presence of Marek's disease in rural farms. The low number of outbreaks in industrial flocks lead us to believe that currently used chicken genetic lines and the vaccinations adopted are in most cases appropriate to counter the circulating viruses, which have mostly a medium-low pathogenic power. The detection of pathogenic viruses in the environment, even in farms with high standards of biosecurity which undergo intensive cleaning and disinfection cycles, highlights the importance of proper vaccination practices

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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