1,721,018 research outputs found

    Le contre-exemple italo-libyen

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    Le 13 juillet 2008 s’est déroulé à Paris le sommet des chefs d’État et de gouvernement de la zone euro-méditerranéenne ; il faisait suite à l’initiative de fondation d’une Union pour la Méditerranée (UPM) du président Nicolas Sarkozy.En 1983, déjà, il y avait eu le Forum méditerranéen (lui aussi à l’initiative de la France) ; puis ce furent les conférences d’abord 5+4

    Radiomics applications in gastrointestinal oncology: the colorectal cancer model

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    Colorectal cancer (CRC) represents the third most common diagnosis of cancer in the worldwide, accounting for around 10% of all new cancer cases globally. Prognosis of patients affected by CRC is strongly dependent on the stage at diagnosis. Besides epidemiologic data, CRC is a complex and heterogeneous disease with different molecular, genetic and epi-genetic sub-types that led to different scenario in the disease course. As a consequence of heterogeneity, tissue sampling biopsy at diagnosis cannot be considered fully representative of tumor behavior and molecular profile. In this context a complete risk stratification to set the best personalized treatment is very important to reduce the risk of recurrence and improve survival. Medical imaging plays a pivotal role in all aspects of personalized medicine: prediction, diagnosis and especially treatment planning, in the choice of the best treatment for the specific patient at the right time. Among the most promising imaging techniques with the potential to improve cancer treatment and outcome, one cannot but include Radiomics. Radiomics is a methodology of advanced quantitative image analysis which uses mathematical algorithms to extract characteristic features from clinical imaging data. Prior studies have evaluated the use of radiomics analysis in CT imaging for adding information about cancer aggressiveness as well as for predicting treatment response. In the colon cancer staging, CT represent the main clinical imaging method to stage the tumor and manage the therapy choices. The major goal of CT is to determine by visual assessment if there is direct invasion of adjacent organs, presence of pathologic lymph nodes and, evidence of distant metastases. Radiomics in colon cancer is proposed to potentially improve characterization and prognosis, mostly using Computed Tomography (CT). The aim of the present thesis is to assess the role of CT imaging-based Radiomics in the colon cancer evaluation at staging to improve disease risk stratification in terms of tumor aggressiveness and lymph node metastasis to manage the best therapeutic approach tailored for the patient at clinical staging

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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