27 research outputs found
CORRIGENDUM to The mechanisms of acute interstitial nephritis in the era of immune checkpoint inhibitors in melanoma
No full textIn this article, the authors’ first names and surnames were incorrectly listed in the wrong order. The correct author list is: Marco Tucci, Anna Passarelli, Annalisa Todisco, Francesco Mannavola, Luigia Stefania Stucci, Stella D’Oronzo, Michele Rossini, Marco Taurisano, Loreto Gesualdo and Franco Silvestris
A short note on compatible operators and their common fixed points in partially ordered sets
No full textWe establish common fixed point theorems for a compatible family of monotone selfmaps of a poset, generalizing previous results of the first author
Enteric neuroplasticity evoked by inflammation
No full textNeuroplastic changes in the enteric nervous system (ENS) may be observed in physiological states, such as development and aging, or occur as a consequence of different pathological conditions, ranging from enteric neuropathies (e.g., Hirschsprung's disease) to intestinal (e.g., inflammatory bowel disease) or extra-intestinal diseases (e.g., Parkinson's disease). Studying ENS plasticity may help to elucidate the pathophysiology of several diseases and have a bearing on the development of new pharmacological interventions. In the present review, we would like to focus on neuronal plasticity evoked by gastrointestinal inflammation occurring in inflammatory bowel disease and in a subset of patients with severe derangement of gut motility due to an enteric neuropathy characterized by an inflammatory infiltrate of the enteric plexuses. Major features of neuroplasticity within the enteric microenvironment encompass structural abnormalities ranging from nerve re-arrangement (e.g., hypertrophy and hyperplasia) to degeneration and loss of enteric ganglion cells; altered synthesis, content and release of neurotransmitters as well as up- or down-regulation of receptor systems; gastrointestinal dysfunction characterized by sensory-motor and secretory impairment of the gut. Interestingly, neuronal changes may also occur in segments of the gastrointestinal tract remote from the site of the original inflammation, e.g. the ileum may show neuroplastic changes during colitis. Sometimes, the inflamed site may even be outside the gut. Among potential mechanisms underlying ENS plasticity, neurotrophins and enteric glia deserve special attention. A better comprehension of ENS plasticity during inflammation could be instrumental to develop new therapeutic options for patients with IBD and inflammatory enteric neuropathies. © 2006 Elsevier B.V. All rights reserved
Correction to: Understanding of historical masonry for conservation approaches: the contribution of Prof. Luigia Binda to research advancement (Materials and Structures, (2018), 51, 6, (140), 10.1617/s11527-018-1254-4)
No full textThe article ‘‘Understanding of historical masonry for conservation approaches: the contribution of Prof. Luigia Binda to research advancement’’, written by ‘‘Anna Anzani, Giuliana Cardani, Paola Condoleo, Elsa Garavaglia, Antonella Saisi, Cristina Tedeschi, Claudia Tiraboschi, Maria Rosa Valluzzi’’, was originally published electronically on the publisher’s Internet portal (currently SpringerLink) on 16 October 2018 without open access. The copyright of the article changed in December 2019 to © The Author(s) 2019, and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made
Impact of humoral autoimmunity in severe gut dismotility: actions of anti-Hu on enteric and visceral sensory neurons.
No full textAutoantibodies as mediators of immuno-neural signaling in the Enteric Nervous System (ENS).
No full textEvaluation of ultraviolet irradiation efficacy in an automated system for the aseptic compounding using challenge test
No full textObjective: Ultraviolet (UV) irradiation efficacy in the intravenous compounding robot APOTECAchemowas evaluated to define the best operative conditions in terms of sterility and time optimization. Design: The challenge test was used against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus subtilis spores and Candida albicans. Inoculated plates were placed inside the robot and irradiated for different times. Microbial air and surface quality inside the equipment were monitored utilizing settle and contact plates, swabs. Results: After 4 h, no microorganisms were viable with killing rates ranging from 5-to 7-log for different microorganisms after 1 h of exposition. In confirmation of the efficacy of the UV irradiation program adopted, the microbial monitoring inside the equipment always gave negative results. Conclusions: This is the first exhaustive investigation of UV irradiation efficacy in the aseptic pharmaceutical production. We demonstrated that UV irradiation plays an essential role in maintaining the sterility condition of the workplace inside the APOTECAchemo and assuring the standards for aseptic manufacturing of medicinal drugs, as required for Class A clean areas. A 4-h UV irradiation also ensures sterility in the case of very resistant microorganisms and in the presence of high microbial charge (108 CFU/ml), but a killing rate of 5 or more is already recorded after the first hour of exposition. The results provide useful information for the best operative conditions in terms of both sterility and time optimization, not only for the automated compounding, but also for the traditional aseptic manufacturing processes. © The Author 2015. Published by Oxford University Press in association with the International Society for Quality in Health Care; all rights reserved
Archivio Elettronico delle Opere di Carlo Emilio Gadda
No full textThe project for the creation of the "Electronic Archive of Carlo Emilio Gadda\u27s Works" was started in 1994, when publisher Garzanti made their published text materials (Gadda, 1988-93), already prepared for photo-composition and for study purposes only, available to the Istituto di Linguistica Computazionale (ILC, Institute of Computational Linguistics). The first version of the Corpus: The Corpus was created starting from these texts (33), appropriately encoded under DBT format and by applying a mark-up to point out various phenomena (italic characters, capital words of proper nouns or decided by the author, hyphens, dates, numbers, formulas, abbreviations, acronyms, pictures, author\u27s and editor\u27s footnotes, dialect and foreign words, dialogue, poetic language). The first version of the Corpus, running in DBT 3.0, was presented on November 14, 1997 (the 104st anniversary of Gadda\u27s birthday) at the CNR (National Research Centre) in Rome
Assessment of Structural and Functional Diversity of Mollusc Assemblages within Vermetid Bioconstructions
No full textDendropoma lebeche is a prosobranch gastropod belonging to the family Vermetidae, which calcifies its shell on hard substrates in dense aggregates, forming biogenic constructions along the western Mediterranean intertidal habitat. It is an important ecosystem engineer and, due to its ecological value, is protected by international convention. The aim of this study is to investigate the mollusc composition and diversity occurring within Spanish vermetid bioconstructions. During the late summer 2013, three distant sites along the Mediterranean coast of Spain were sampled by scraping off the vermetid shells to study their associated assemblages. A total of 600 molluscs were identified within the classes of Polyplacophora (four species), Gastropoda (35 spp.) and Bivalvia (18 spp.). Multivariate analyses revealed significant differences in composition and trophic diversity of mollusc assemblages among the three sites, highlighting a clear geographical gradient. Overall, both herbivores (grazers and deposit feeders) and omnivores were the quantitatively dominant trophic groups, while carnivores (predators and ectoparasites) were very scarce. Our results point out that mollusc assemblages associated with vermetid bioconstructions are rich and diversified, both in populations structure and trophic diversity, confirming the important role of vermetid gastropods as ecosystem engineers and biodiversity enhancers in shallow coastal waters.This study was funded by the Italian Ministry for Education, Universities and Research (Z8HJ5M_008; P.R.I.N. Program 2010–2011: project “Marine bioconstructions: structure, function and management”), and by a Ph.D. fellowship of the first author L.D. (Doctorate in Marine, Terrestrial and Climate Sciences, University of Naples Parthenope)
