87,639 research outputs found

    Noce

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    Neri D., Cozzolino E., Massetani F., 2022. Noce. In: Arboricoltura speciale. Gentile, Inglese, Tagliavini Eds. Edagricole. Pp. 429-456

    STURGEON GENETICS AND CYTOGENETICS: RECENT ADVANCEMENTS AND PERSPECTIVES

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    The aim of this review is to introduce current knowledge in the field of sturgeon genetics. The first section deals with sturgeon cytogenetics, reviewing karyotype organization and polyploidization events during evolution of Acipenseriformes. The second section concerns the results of applications of molecular biology to studies of phylogenetic relationships between extant species, intraspecific analysis of wild populations and stocks for conservation purposes, together with characterization of molecular markers for species identification, relevant to forensic and conservation issues

    Clinical features, pathophysiology and management of fatal familial insomnia

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    Introduction: Fatal Familial Insomnia (FFI) is an inherited prion disorder caused by a point mutation at codon 178 of the PRNP gene, resulting in aspartic acid to asparagine substitution (D178N) in coupling phase with methionine at position 129. The disease is associated with sleep alterations, autonomic dysfunctions, loss of weight and motor signs. After symptoms onset, the disease usually leads to death within 2 years and no treatments are available at present. Areas covered: This review focuses on classical and innovative aspects of FFI, with special emphasis on recent indications that infectious prion are not only confined to the central nervous system but can be detected in peripheral tissues of diseased patients. Expert opinion: Although FFI can be genetically diagnosed, the ability of innovative techniques to specifically detect minute amount of infectious prion in peripheral tissues (such as the olfactory mucosa) is of fundamental importance for disease monitoring and to evaluate the efficacy of specific treatments to interfere with disease progression. Overall, the ability of these techniques to mimic the process of prion propagation in vitro can be exploited to perform preliminary high throughput screenings of compounds in order to select the most effective for FFI treatment

    A hierarchical dataset of vegetative and reproductive growth in apple tree organs under conventional and non-limited carbon resources

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    A monitoring of apple fruit, shoot and trunk growth was performed on 15 trees, equally split according to three treatments, which determined heavily contrasting carbon assimilate availability: unmanipulated trees (FRU), thinned trees (THI) and defruited trees (DEF). Several variables describe the vegetative growth on FRU and DEF trees (shoot length, base diameter, number of fruits on shoot, and height, diameter, pruning intensity and number of fruits of the branch carrying the shoot; trunk circumference), as well as the fruit growth on FRU and THI trees (3 fruit diameters). Additional measurements from ancillary shoots (apical diameter, number of leaves, leaf dry weight, stem dry weight, fresh mass, volume) and fruits (3 diameters, dry weight) from trees undergoing the same treatments, provide a more complete (destructive) characterization of organs growth, thanks to several measurements performed across the growing season. Organs are provided with categorical variables indicating the treatment, tree, canopy height, orientation (for both shoots and fruit), as well as branch and shoot identifiers, so that hierarchical modeling of the dataset can be performed. The dataset is completed with dates and day of the year of the measurements and the accumulated growing degree days from full bloom. Data can be used to calculate apple tree absolute and relative growth rates, maximum potential growth rates, as well as shoot growth responses to thinning and pruning. The dataset can also be used to calibrate allometric relationships, estimate structural apple tree growth parameters and their variabilit

    Modelli animali di miopatie

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