39 research outputs found
VARIABILITY OF WINTER RUNOFF OF THE OKA RIVER AND ITS RELATIONSHIP WITH CLIMATE CHANGE
Get PDFResponse of a river flow in a winter low-water period to the climate changes is analyzed by the example of theOkaRiver(245 thousand km2). The analysis was done for each individual month from December to March during the period 1980–2015. The data were obtained for the hydrometric section Oka–Gorbatov. The following climatic characteristics were used for the analysis: 1) the number of days with positive air temperatures; 2) the temperature of the upper soil layer; 3) the sum of precipitation (data of meteorological station); 4) water equivalent of snow (the data from the satellite ESA GlobSnow, SWE version 2). Accuracy of the satellite data was estimated with respect to the observational data. In 1981–2010, significant increase in winter runoff occurred in December and March. This period was divided into two phases: 1) the end of the 20th century which was characterized by increasing of precipitation, the soil temperature, number of days with positive temperatures, and that resulted in the growth of the water equivalent of snow; 2) the beginning of the 21st century – by significant fluctuation in precipitation, number of days with positive temperatures as well as by a drop in the soil temperature and water equivalent of snow. The runoff volume was found to be in a direct relationship with the number of days with positive temperatures, the soil temperature, the precipitation sum, and in the inverse relationship with the water equivalent of snow. Both, the regression and dispersion analyses indicated that the above set of climatic characteristics was sufficient to explain changes in the winter runoff. According to the degree of influence on the winter runoff, these characteristics can be ranked as follows: the number of days with positive temperatures; the average soil temperature; the water equivalent of snow; the precipitation sum. The effect of the water equivalent on the runoff becomes significant from midwinter and remains the most significant factor by the end of snowmelt
Ppofessional risk industry factors = Професійні фактори ризику в умовах виробництва = Профессиональные факторы риска в условиях производства
Get PDFPopova T. M., Melnyk O. G., Bagmut I. Yu., Riabokon A. I., Titkova A. V. Ppofessional risk industry factors = Професійні фактори ризику в умовах виробництва = Профессиональные факторы риска в условиях производства. Journal of Education, Health and Sport. 2016;6(11):511-519. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.192143
http://ojs.ukw.edu.pl/index.php/johs/article/view/4032
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).
755 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Author (s) 2016;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 02.11.2016. Revised 22.11.2016. Accepted: 30.11.2016.
UDK 613.6.027: 663.97.05
PROFESSIONAL RISK INDUSTRY FACTORS
T. M. Popova, *O. G. Melnyk, I. Yu. Bagmut, *A. I. Riabokon, A. V. Titkova
Kharkiv Medical Academy of Postgraduate Education;
*Kharkiv National Medical University
Summary
The hygienic estimation of the main workplace conditions at the tobacco production is presented in this article. The process of tobacco production is divided into two important stages: preparation of tobacco and the production of cigarettes. The first stage occurs in the tobacco department and second ones takes place in the cigarette department. The tobacco department workers are exposed to elevated concentration of tobacco dust 6,5 mg/m3 (maximum permissible concentration (MPC) 3,0 mg/m3), noise level is 82-83 dBA that more maximum permissible limit (MPL 80 dBA) for 8 hours working period and adverse microclimate. During eight hours the cigarette department workers are exposed to high noise level 82-83 dBA, the same as previous stage, but concentration of tobacco dust is not higher than MPC.
By results of the estimation of working conditions at the tobacco factory among the basic harmful and dangerous production factors are the tobacco dust, industrial noise, adverse microclimate, severity and intensity of work.
Key words: occupational risk factors, tobacco dust, industrial noise.
ПРОФЕСІЙНІ ФАКТОРИ РИЗИКУ В УМОВАХ ВИРОБНИЦТВА
Т. М. Попова, *О. Г. Мельник, І. Ю. Багмут, *А. І. Рябоконь, А. В. Тіткова
Харківська медична академія післядипломної освіти;
*Харківський національний медичний університет
Резюме
У статті наведена гігієнічна характеристика умов праці робітників основних цехів виготовлення тютюнових виробів. Процес виробництва сигарет вміщує два важливих етапи: підготовки тютюну і власне виробництво цигарок та сигарет. Перший етап відбувається у тютюновому цеху, а другий – у цигарково-сигаретному. Визначено, що робітники тютюнового цеха працюють в умовах тривалого впливу підвищених концентрацій тютюнового пилу 6,5 мг/м3, що перевищує ГДК на 3,5 мг/м3, підвищеного рівня шуму – 82-83 дБА (вище за ГДР на 2-3дБА) та несприятливих мікрокліматичних умовах. Щодо цигарково-сигаретного цеху, то його працівники, протягом 8 годин, піддаються впливу тютюнового пилу (концентрація у межах ГДК), дії підвищеного рівня шуму (вище за ГДР на 2-3дБА).
За результатами оцінки умов праці на тютюновій фабриці серед основних шкідливих і небезпечних виробничих факторів виробництва є тютюновий пил, промисловий шум, несприятливий мікроклімат, важкість і інтенсивність праці.
Ключові слова: професійні фактори ризику, тютюновий пил, виробничий шум.
ПРОФЕССИОНАЛЬНЫЕ ФАКТОРЫ РИСКА В УСЛОВИЯХ ПРОИЗВОДСТВА
Т. М. Попова, *О. Г. Мельник, И. Ю. Багмут, *А. И. Рябоконь, А. В. Титкова
Харковская медицинская академия последипломного образования;
*Харковский национальный медицинский университет
Резюме
В статье дана гигиеническая характеристика рабочих мест основных цехов производства табачных изделий. Процесс производства сигарет включает два важных этапа: подготовка табака и собственное производство папирос и сигарет. Первый этап происходит в табачном цехе, а второй – в папиросо-сигаретном. Установлено, что рабочие табачного цеха работают в условиях длительного воздействия повышенных концентраций табачной пыли 6,5 мг/м3, которая превышает ПДК в 3,5мг/м3, повышенного уровня шума - 82-83 дБА (ПДУ 80 дБА), неблагоприятных микроклиматических условий. В папиросо-сигаретном цехе в течение трудового дня на рабочих воздействует табачная пыль (концентрация в пределах ПДК), производственный шум 82-83 дБА (ПДУ 80 дБА).
По результатам оценки условий труда на табачной фабрике среди основных вредных и опасных производственных факторов является табачная пыль, промышленный шум, неблагоприятный микроклимат, тяжесть и интенсивность труда.
Ключевые слова: профессиональные факторы риска, табачная пыль, производственный шум
The influence of sub-toxic dose xenobiotic on immune response of experimental animals = Вплив субтоксичних доз ксенобіотиків на імунну відповідь у експериментальних тварин = Влияние субтоксических доз ксенобиотиков на иммунный ответ у экспериментальных животных
Get PDFBagmut I. Yu., Popova T. M., Titkova A. V., Philipchenko S. M., Shepylieva N. V. The influence of sub-toxic dose xenobiotic on immune response of experimental animals = Вплив субтоксичних доз ксенобіотиків на імунну відповідь у експериментальних тварин = Влияние субтоксических доз ксенобиотиков на иммунный ответ у экспериментальных животных. Journal of Education, Health and Sport. 2016;6(11):629-639. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.200862
http://ojs.ukw.edu.pl/index.php/johs/article/view/4066
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).
755 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Author (s) 2016;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 02.11.2016. Revised 22.11.2016. Accepted: 30.11.2016.
UDK 613.6.027: 663.97.05
THE INFLUENCE OF SUB-TOXIC DOSE XENOBIOTIC
ON IMMUNE RESPONSE OF EXPERIMENTAL ANIMALS
I. Yu. Bagmut, T. M. Popova, A. V. Titkova, S. M. Philipchenko, N. V. Shepylieva
Kharkiv Medical Academy of Postgraduate Education
Summary
The polyester is widely used in all sectors of the economy. The polyester influence on the cellular and humoral immunity has been required an integrated research. The actual medical-biological problem is immune deficiency indicators and they need to substantiate during immune toxicological research. One of the scientific directions is the investigation of polyols influence on immunobiological resistance of the human organism. The results can be used for developing of methods to increase the non-specific reactivity.
This study examines mechanisms of cellular and humoral immunity disorders of mice and rats after prolonged oral administration of Laprol- 604. Oral consumption of Laprol-604 has been shown to result in inhibition of cellular and humoral immunity of laboratory animals. The study has been performed as part of the research topic of Kharkiv Medical Academy of Postgraduate Education «Cellular-molecular mechanisms of inflammation associated with chronic diseases», the state registration number 015U001186.
Keywords: polyester, Laprol-604, humoral immunity, cellular immunity, spleen, lymph nodes.
ВПЛИВ СУБТОКСИЧНИХ ДОЗ КСЕНОБІОТИКІВ НА ІМУННУ ВІДПОВІДЬ
У ЕКСПЕРИМЕНТАЛЬНИХ ТВАРИН
І. Ю. Багмут, Т. М. Попова, А. В. Тіткова, С. М. Філіпченко, Н. В. Шепілева
Харківська медична академія післядипломної освіти
Резюме
Поліестер широко використовується у всіх секторах економіки. Вплив поліестеру на вираженість клітинного та гуморального імунітет вимагає комплексного дослідження. Важливою медико-біологічною проблемою є показники імунодефіциту, що і було вивчено при імунних токсикологічних дослідженнях. Одним з наукових напрямків є вивчення впливу поліолів на імунобіологічну резистентність організму людини. Отримані результати можуть бути використані для розробки методів підвищення неспецифічної реактивності.
У даній роботі розглядаються механізми порушень клітинного і гуморального імунітету у мишей і щурів після тривалого перорального введення Лапрола-604. Показано, що пероральне введення Лапрола-604 призводить до пригнічення клітинного і гуморального імунітету у тварин. Дослідження було проведено в рамках науково-дослідної теми Харківської медичної академії післядипломної освіти «Клітинно-молекулярні механізми запалення, пов'язані з хронічними захворюваннями» (номер державної реєстрації 015U001186).
Ключові слова: поліестер, Лапрол-604, гуморальний імунітет, клітинний імунітет, селезінка, лімфатичні вузли.
ВЛИЯНИЕ СУБТОКСИЧЕСКИХ ДОЗ КСЕНОБИОТИКОВ НА ИММУННЫЙ ОТВЕТ У ЭКСПЕРИМЕНТАЛЬНЫХ ЖИВОТНЫХ
И. Ю. Багмут, Т. М. Попова, А. В. Титкова, С. М. Филипченко, Н. В. Шепилева
Харьковская медицинская академия последипломного образования
Резюме
Полиэстер широко используется во всех секторах экономики. Влияние полиэстера на выраженность клеточного и гуморального иммунитет требует комплексного исследования. Важной медико-биологической проблемой являются показатели иммунодефицита, что и было изучено при иммунных токсикологических исследованиях. Одним из научных направлений является изучение влияния полиолов на иммунобиологическую резистентность организма человека. Полученные результаты могут быть использованы для разработки методов повышения неспецифической реактивности.
В настоящей работе рассматриваются механизмы нарушений клеточного и гуморального иммунитета у мышей и крыс после длительного перорального введения Лапрола-604. Показано, что пероральное введение Лапрола-604 приводит к угнетению клеточного и гуморального иммунитета у животных. Исследование было проведено в рамках научно-исследовательской темы Харьковской медицинской академии последипломного образования «Клеточно-молекулярные механизмы воспаления, связанные с хроническими заболеваниями» (номер государственной регистрации 015U001186).
Ключевые слова: полиэстер, Лапрол-604, гуморальный иммунитет, клеточный иммунитет, селезёнка, лимфатические узлы
Winter positions of Arctic front during periods of cooling and warming
Get PDFWinter positions of the Arctic front (AF) during the known periods of the climate cooling (1949–1980) and warming (1981–2012) were analyzed within the sector 10° W – 60° E. The AF positios were determined by the following indicators: 1) a surface pressure; 2) horizontal wind divergence; 3) geostrophic vortex; 4) geostrophic heat advection. The main extrema of these four dynamic characteristics coincide and fall on the latitude 72.5° N. This corresponds to the average position of the AF for a given resolution and confirms correctness of our choice of these characteristics as the AF indicators. Relative differences between mean profiles of all values of the above warm and cold periods were calculated using method of normalization of each value for the corresponding latitude by the standard deviation for the entire period (1949–2012). To study variability of the AF position we used mean yearly winter profiles of the variables under investigation together with the statistical analysis of positions of the extrema within the latitude degrees. For pressure and geostrophic advection positions of the absolute minima were determined while for geostrophic vortex and divergence – positions of the absolute maxima. The data show that according to different criteria the AF average positions for the period 1949–2012 lie within the zone 72.4–73.4 N. The interannual variability of the AF positions lies within the 1–2 degrees of latitude and corresponds to the range of the air temperature variability above the zone of maximal changes in the sea ice area. According to the standard deviation values of the divergence and the geostrophic vortex are the most stable in region of the AF passage. Comparison of differences of the studied characteristics between the warm and cold periods shows that the changes in the AF positions are not statistically significant (P(t) < 91% t‑criterion) unlike the changes in positions of isolines which characterize the warming (P(t) = 100%). Thus, despite significant changes in properties of the surface and the temperature regime to the north of 72.5 N (the warming), according to all the criteria the AF climatic position remains quasi‑stationary for 32‑year periods of averaging
THE STUDY OF PATHOPHYSIOLOGICAL LINK OF AUTOIMMUNIZATION IN PATIENTS WHO USE SOFT CONTACT LENSES
Get PDFIn this work, the state of the immune system was studied in thepatients using soft contact lenses for various variants of the normal microflora eyes. Analyzing the absolute number of lymphocytes in the peripheral blood, we found that these indices are within the limits of normal physiological fluctuations and do not have a significant difference between the groups. The same tendency was observed in the study of the content of common T-lymphocytes, and their number in all groups is within the limits of normal physiological parameters. The inhibition of the IL-2 expression activator confirms our assumption of latent suppression of the T-immune system, especially in patients who have a smoking habit. It has been found that in patients who use soft contact lenses and have a habit of smoking there is a decrease in the level of B-lymphocytes. However, despite the normal immunological parameters of B-lymphocytes, in the 1st group as well as in the 2nd group there is a hidden inhibition of the T-immune system
Using ERA5–Land Reanalysis and Data from Weather Stations in the Mountainous Regions of Russia to Assess Changes in the Glacial Systems of Eastern Siberia and the Far East
No full textThis work involving the study of changes in the glacier equilibrium line altitude (ELA) is a continuance of the glaciological parameters of mountain systems investigation. The article explores the possibility of using new generation climate archives (in this case, ERA5–Land) together with weather station data on temperature and precipitation, in order to assess the climate dependence of the glacial system ELA in hard-to-reach and insufficiently studied mountain regions of the Russia Asian part. The ERA5–Land reanalysis reproduces temperature (values, dynamics, and trends) quite well in mountain systems. The use of total precipitation is possible only for assessing their dynamics and trends. The relative error for temperature trend is below 20% in both positive and negative sides, and precipitation is less than 30% in the negative one. Positive temperature trends of different intensity are observed in all mountains of the Russia Asian part with a maximum in the mountain systems of the Arctic zone. Minimal temperature trends are distinctive for coastal mountain regions of temperate latitudes. Summer temperature trends are maximum in inland areas and minimum in coastal mountain areas. The increase in precipitation in such areas occurs mainly at the expense of the cold period. It was revealed there was an increase of the glacial systems ELA from 50 to 800 m in the mountain regions of the Asian North Russia within 1966–2021. The value of the ELA rise coincides with areas of high temperature trends and may not correspond to precipitation negative trends
Snow occurrence time on the Russia’s territory in the early 21st century (from satellite data)
Get PDFTime of the snow cover appearance, existence and disappearance on the Russia’s territory in the early 21st century (2000–2015) was corrected using the MODIS/Terra satellite data (the 8-day discreteness, and the 0.5×0.5° resolution). The satellite data errors were estimated from data of the ground stations observations. The errors were found to be maximal in autumn and minimal in spring. The relationship between the snow cover characteristics and the climate ones was investigated using data obtained at the ground-based stations together with correlation between dates of snow appearance and loss and the climate parameters. The dependences obtained were tested by means of correlation and regression analysis over the longitudinal sectors. Significant coefficients of correlation (the Student criterion of probability was equal to 0.95) were found between time of the snow cover presence and dates of the temperature drop below 0 °С and the amount of days with negative temperatures. Changes in the climate characteristics result in that due to decreasing of the solid precipitation in winter time the snow presence duration becomes shorter over the European part of Russia and in the Western Siberia. The shortening in the Middle Siberia is caused by the spring warming. Durations of the snow occurrence in the Far East area are different. On the Chukotka peninsula the duration is longer because of the autumn fall in temperature while in the Kamchatka region the snow occurrence time is shorter due to significant decrease of a period with negative temperatures in both the autumn and spring seasons
Changes in Climate and Snow Cover in View of Functioning of Ski Resorts in Russia in the Early 21th Century
No full textThe development of winter ski tourism and characteristics of ski resorts in various regions of Russia are closely related to climatic conditions, the most important of which are the presence and duration of snow cover. For the period 2000–2021, a study of snow cover, availability of “optimal ski days” and climatic indicators necessary for artificial snowmaking at ski resorts located in different regions of Russia was performed, using data of the reanalysis ERA5-Land. The characteristics of snow cover and temperature from the reanalysis data were compared with data of the meteorological network. The ERA5-Land data for temperature, precipitation, and snow cover thickness are well synchronized with the observational data, and estimates of the error of trends in air temperature and snow cover depth according to the reanalysis data relative to the station data give satisfactory results. In the conditions of the current climate, the average and maximum thickness of snow cover in all resorts is sufficient for their functioning, but in 2000–2021, a decrease in both the maximum and average values of snow cover is noted in most resorts. The study shows that in terms of snow and weather conditions, the highest mountain resorts of the North Caucasus and Kirovsk (Murmansk region) are the most prosperous, where thickness of the snow cover and duration of its occurrence as well as a significant number of “optimal ski days” sustains stability of the resorts and creates favorable conditions for their further development
Effect of Warm Atlantic Waters on the Climate Anomalies in the West Arctic
Get PDFSignificant climatic changes of oceanic and atmospheric elements and a relation of them to the ocean surface winter anomalies in North Atlantic are analyzed in the paper. Periods of «warm» ocean (2002–2012) and «cold» ocean (1960–1970) were determined. Positive anomalies of the ocean surface temperature increase the ice-free water area and, correspondingly, decrease the ice-field area. As a result of such changes in a state of the ocean surface (open water and ice), surface air temperature rises, and, consequently, atmospheric pressure in central part of a given Arctic sector drops
